清醒的扑火飞蛾--从《夜莺与蔷薇》看王尔德的矛盾性

长期以来,奥斯卡·王尔德被公认为是充满矛盾性的唯关主义的代表人物.童话<夜莺与蔷薇>就成功地反映出了王尔德的唯美主义理论及其对自身理论的反思与困惑.王尔德对世界进行的艺术世界与现实世界的二元划分,对脱离生活的纯粹艺术的追求,是造成其矛盾性的根源.     

Protein Subcellular Localization Prediction and Genomic Polymorphism Analysis of the SARS Coronavirus

Introduction In March 2003, a novel coronavirus (CoV) was dis-covered in association with the outbreak of severe acute respiratory syndrome (SARS)[1-3]. The complete genome sequence of several SARS-CoV isolates was soon determined and characterized[4,5]. Comparison of variant SARS-CoV genome sequences has identified certain genetic signatures that can be used to trace sources of infection[6]. Vaccines are now being devel-oped and molecular modeling has suggested that modi-fied rhinovir…     

自尊对生命意义感的预测机制 ——心理控制源和积极情绪的中介作用

基于自尊预测生命意义感的研究结果, 引入心理控制源和积极情绪两个变量作为中介变量, 分别从认知和情绪的角度探索自尊对生命意义感的预测机制。实验前采用自尊量表、心理控制源行为量表、情绪量表和生命意义感问卷分别测量被试的心理控制源、积极情绪以及生命意义感, 用表达性写作的方法, 分别启动被试的自尊水平, 最后再次测量被试的心理控制源、积极情绪和生命意义感, 用重复测量方差分析方法考察启动自尊对心理控制源、积极情绪和生命意义感的影响, 用分层回归和Bootstrap检验心理控制源和积极情绪对自尊和生命意义感的中介作用。结果表明, 启动自尊会显著影响被试的心理控制源、积极情绪和生命意义感, 心理控制源和积极情绪在自尊与生命意义感之间起中介作用。     

基因组学与地球科学迅猛发展,古生物学进入纵深发展新时代——2017年古生物学热点回眸

 古生物学是以化石为主要研究对象,研究地质历史时期的生物界及其发展的科学,属于地球科学与生命科学之间的交叉学科。随着生命科学基因组学与地球系统科学的迅猛发展,古生物学这门古老学科进入了纵深发展的新时代,不断涌现振奋人心的研究进展与新发现。本文回顾了2017年国际古生物研究领域取得的重要进展与研究热点,并介绍了中国古生物学界2017年在早期生命、早期后口动物、古脊椎动物、古人类、古DNA以及演化古生物学等研究方向做出的重要贡献。     

文理兼收护理学专业医用化学课程的改革

护理学专业文理兼收模式下，通过优化教学内容，采用“基于团队的导学教学法”和实现课堂微课化等改革措施，达到了培养学生团队协作能力、自主学习能力，提高学习效果的目的。     

Closed paths of light trapped in a closed Fermat curve

Geometric constructions have previously been shown that can be interpreted as rays of light trapped either in polygons or in conics, by successive reflections. The same question, trapping light in closed Fermat curves, is addressed here. Numerical methods are used to study the behaviour of the reflection points of a triangle when the degree of the curve varies, including a generalization to non integer powers.     

论蒋捷词的爱国与隐逸情怀

蒋捷是宋末元初词人,经历了宋元易代之际的巨大动荡,承受着国破家亡之痛、身世飘零之苦,用词记录下万千郁抑、悲慨、哀痛、愁怨、落寞与无奈,爱国情思蕴育其间,最终在山水风景、闲适生活中寻找到恬淡、悠然、平静的快乐,流露出其遗世独立、清逸高洁的节操。     

Improved RP‐HPLC method for determination of bovine lactoferrin and its proteolytic degradation in simulated gastrointestinal fluids

The objective of this study was to qualitatively and quantitatively evaluate bovine lactoferrin (bLf) and its stability using a rapid RP‐HPLC method. bLf could be rapidly detected within 20 min and quantitated at levels down to 5 µg/mL, and the equation of linearity was y = 86.10x + 178.31 with the correlation coefficient (r²) 0.9997. Quantitative data obtained in the present study proved the improved RP‐HPLC method to be a sensitive and accurate analytical tool for bLf determination. The proteolytic cleavage of bLf in simulated human gastrointestinal fluids was further analyzed by RP‐HPLC, and found to follow pseudo‐first‐order kinetics. The typical equation obtained by pepsin was log₁₀ [A_t]/[A₀] = ?0.03x (r² = 0.85), and log₁₀ [A_t]/[A₀] = ?0.01x (r² = 0.81) for trypsin and chymotrypsin combination. Pepsinolysis of bLf in simulated gastric fluid was relatively fast with the half‐life t_1/2 23.1 min. The digestion of bLf in simulated intestinal fluid was slower with about a 3‐fold increase in half‐life (69.3 min). After the complete proteolysis of bLf, small cleaved peptide fragments were fully separated and identified by RP‐HPLC. The proteolytic study indicated that this validated RP‐HPLC was able to evaluate bLf stability though monitoring the derivatization products. Copyright © 2012 John Wiley & Sons, Ltd.     

以需求为导向挖掘服务体系的利基市场——关于加速构建滨海新区产业服务体系研究的实证

近年来滨海新区产业集群逐步形成,而服务体系资源匮乏、专业化程度不够、服务模式单一等问题也逐一显现。围绕结合企业生命周期针对不同产业并寻找当中未被挖掘的或者说未被很好满足的服务利基市场,构建以需求为导向的、多层次具有滨海新区产业环境特色的、与产业发展无缝对接的高效服务体系展开实证分析。     

知识分子精神的日常消解

在中国社会发展的历史进程当中，知识分子的社会身份和文化属性一直处于变动之中，今天的知识分子面临着更为复杂、多元的社会现实。李洱、孙瑜等当代作家通过小说叙事对于知识分子的生存现状进行了深入、细致的考察，向我们展示了一个普遍化的社会现实：知识分子精神生活的日常消解，成为现代社会中积郁已久的“文化病”。