A Novel One Pot Synthesis of o‐Nitrophenylacetic Acid and Unexpected p‐Nitrobenzoic Acid by HNO3‐Mediated CH2 Extrusion Reaction of Phenylacetic Acid

The HNO₃‐mediated CH₂ extrusion reactions of phenylacetic acid lead to one pot synthesis of unexpected commercially important product 4‐nitrobenzoic acid through the formation of 4‐nitrophenylacetic acid and 2‐nitrophenylacetic acid.     

Towards a black‐box for biological EXAFS data analysis. II. Automatic BioXAS Refinement and Analysis (ABRA)

In biological systems, X‐ray absorption spectroscopy (XAS) can determine structural details of metal binding sites with high resolution. Here a method enabling an automated analysis of the corresponding EXAFS data is presented, utilizing in addition to least‐squares refinement the prior knowledge about structural details and important fit parameters. A metal binding motif is characterized by the type of donor atoms and their bond lengths. These fit results are compared by bond valance sum analysis and target distances with established structures of metal binding sites. Other parameters such as the Debye–Waller factor and shift of the Fermi energy provide further insights into the quality of a fit. The introduction of mathematical criteria, their combination and calibration allows an automated analysis of XAS data as demonstrated for a number of examples. This presents a starting point for future applications to all kinds of systems studied by XAS and allows the algorithm to be transferred to data analysis in other fields.     

浅谈公共图书馆自动化的发展

阐述了图书馆自动化发展的历程,分析了国内图书馆自动化发展的现状及面临的问题,提出了图书馆自动化发展的建议。     

曲靖旅游产业升级策略研究

旅游业作为第三产业的支柱产业之一，低污染、低能耗的特点使其备受各级政府的重视。曲靖市旅游业拥有宜人的气候、丰富的资源、发达的经济等优势，但是也存在着观光旅游的景点知名度相对较低、基础性公共服务部门的服务意识薄弱、旅游配套设施不足等问题。为此，应通过科学规划，大力发展休闲游、自驾游等方式，以促进整个旅游业的产业升级。     

工伤认定标准的几个法律问题

对上下班途中发生的交通事故、职工"过劳死",以及由于工作压力过大造成的精神损害是否一律认定为工伤问题进行了探讨。提出,是否认定为工伤不仅要依据相关的法律规定,更要有一个统一的工伤认定原则,即事故的发生是否"与工作有关",凡是"与工作有关"就应当认定为工伤,反之,则应以非工伤处理。     

食品包装机械的自动控制

食品包装机械自动化有利于提高设备的生产率，满足人们日益增长的生活需求，保证食品包装的一致性和安全性. 指出要实现食品包装机械自动化，需要考虑包括控制器、传感器、伺服驱动技术、人机交互界面及网络技术等问题；同时从食品包装机械自动化的发展趋势看，要加强对设备的数控化，设备信息的一体化及设备故障诊断的智能化等方面的研究.     

Industrial Applications of Dimeric Surfactants: A Review

Dimeric surfactants also known as gemini surfactants have received lots of attention for high performance formulations in the various scientific and commercial products. Due to the greater amount of hydrocarbon per molecule, the critical micelle concentrations (CMC) of dimeric are typically one order of magnitude lower than the corresponding monomeric surfactant. They are ten to hundred times more efficient at reducing the surface tension of water and the interfacial tension of the oil-water interface than conventional surfactants. Besides, the Krafft temperatures of gemini surfactants with hydrophilic spacers are generally very low giving these surfactants the capacity to be used in cold water. These surfactants display a range of interesting properties, including elevated surface activity, extremely low CMC and extraordinary rheology and self-assimilation aspect. As a consequence of these properties, they have many potential applications include detergents and cleaning agents, cosmetics, textile, and dyeing, dispersion stabilization and emulsion polymerization, genetics science, pharmaceutical, and biological applications.      

化学工程:从基础研究到工业应用

本文介绍了我国中长期发展规划中所制定的化学化工学科发展目标,综述了化学工程学科近十余年来在队伍建设、平台建设和国家级奖励等方面所取得的成果,列举了若干化学工程在传递与过程强化、化工分离过程、精细与药物化工、能源化工和材料化工领域从基础研究到工业化应用的例子和成果,展望了化学工程学科今后发展的方向及目标.     

Photochemical Synthesis of the Bioactive Fragment of Salbutamol and Derivatives in a Self-Optimizing Flow Chemistry Platform

The implementation of self-optimizing flow reactors has been mostly limited to model reactions or known synthesis routes. In this work, a self-optimizing flow photochemistry platform is used to develop an original synthesis of the bioactive fragment of Salbutamol and derivatives. The key photochemical steps for the construction of the aryl vicinyl amino alcohol moiety consist of a C−C bond forming reaction followed by an unprecedented, high yielding (>80 %), benzylic oxidative cyclization.     

FeO(OH)@C-Catalyzed Selective Hydrazine Substitution of p-Nitro-Aryl Fluorides and their Application for the Synthesis of Phthalazinones

An efficient hydrazine substitution of p-nitro-aryl fluorides with hydrazine hydrates catalyzed by FeO(OH)@C nanoparticles is described. This hydrazine substitutions of p-nitro-aryl fluorides bearing electron-withdrawing groups proceeded efficiently with high yield and selectivity. Similarly, hydrogenations of p-nitro-aryl fluorides containing electron-donating groups also smoothly proceeded under mild conditions. Furthermore, with these prepared aryl hydrazines, some phthalazinones, interesting as potential structures for pharmaceuticals, have successfully been synthesized in high yields.