心肌动作电位对心脏节律的影响

采用数值方法分析心肌动作电位对心脏节律的影响。心肌动作电位用Noble模型来描述，心脏节律用Bernardo-Signorint模型来模拟。数值分析结果表明，心肌动作电位形成的靶环波和螺旋波对心脏节律影响较大。当心肌动作电位表现为噪声时，心脏节律可完全破坏。     

洛希极限和引力作用范围的近似改正

运用广义相对论的后牛顿效应，得到洛希(Roche)极限和引力作用范围的近似改正表示式，表明洛希极限不仅与牛顿引潮力及惯性离心力有关，而且受重力后牛顿近似改正的影响。并且估计、讨论了太阳系天体的某些具体情况。     

Ring‐opening grafting polymerization of cyclic monomers onto human hair

Natural human hair was successfully modified by the graft polymerization of trimethylene carbonate, β‐propiolactone, ε‐caprolactone, glycidol, ε‐caprolactam, and 5,5‐dimethyl‐1,3‐dioxane‐2‐thione. In contrast, we could not modify natural human hair by the graft polymerization of oxetane under similar conditions. The model reaction suggested that the main initiating species in these polymerizations were the amino, thiol, and hydroxyl groups in hair, which could induce ring‐opening polymerization. Among the tested monomers, β‐propiolactone was most effective for hair modification with its graft polymer, whose concentration was as high as 0.5 g/g of hair though polymerization under mild conditions. The effects of the hair pretreatment and polymerization temperature on the weight ratio of the grafted polymers were also investigated. Hair modified by grafted polymers was characterized with scanning electron microscopy and Fourier transform infrared measurements. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 45: 736–744, 2007     

Interpretation of inorganic arsenic metabolism in humans in the light of observations made in vitro and in vivo in the rat

The toxicity of inorganic trivalent arsenic for living organisms is reduced by in vivo methylation of the element. In man, this biotransformation leads to the synthesis of monomethylarsonic (MMA) and dimethylarsinic (DMA) acids, which are efficiently eliminated in urine along with the unchanged form (As_i). In order to document the methylation process in humans, the kinetics of As_i, MMA and DMA elimination were studied in volunteers given a single dose of one of these three arsenicals or repeated doses of As_i. The arsenic methylation efficiency was also assessed in subjects acutely intoxicated with arsenic trioxide (As₂O₃) and in patients with liver diseases. Several observations in humans can be explained by the properties of the enzymic systems involved in the methylation process which we have characterized in vitro and in vivo in rats as follows: (1) production of As_i metabolites is catalyzed by an enzymic system whose activity is highest in liver cytosol; (2) different enzymic activities, using the same methyl group donor (S-adenosylmethionine), lead to the production of mono- and di-methylated derivatives which are excreted in urine as MMA and DMA; (3) dimethylating activity is highly sensitive to inhibition by excess of inorganic arsenic; (4) reduced glutathione concentration in liver moderates the arsenic methylation process through several mechanisms, e.g. stimulation of the first methylation reaction leading to MMA, facilitation of As_i uptake by hepatocytes, stimulation of the biliary excretion of the element, reduction of pentavalent forms before methylation, and protection of a reducing environment in the cells necessary to maintain the activity of the enzymic systems.     

论民事抗诉的原则

民事抗诉的原则包括维护司法公正与权威原则、有限监督救济与减少诉累原则、居中监督与效宰经济原则等三个基本的抗诉原则。     

运动员人力资本的不确定性与足球职业俱乐部治理特征

人力资本是分析职业足球俱乐部的治理结构的起点,人力资本的各种特征所内含的不确定性将在足球俱乐部治理和俱乐部的持续发展中起核心作用.通过分析运动员的人力资本特征,主要包括:运动员是其人力资本的“自然”所有者和承担者,具有不可分性,走运动员的主动资产;运动员人力资本具有不完全替代性,并通过团队活动获得不同程度的垄断权力,有获取报酬递增的趋势;以及运动员人力资本的不确定性.俱乐部最重要的资产是运动员的人力资本资产,因此,俱乐部必须充分考虑运动员行为的不确定性,其治理结构必须符合人力资本的特征,激励合约必须面向未来.     

论激励机制在国有企业中的运用

介绍了激励管理的内涵,并就国有企业如何建立和运用高效的激励机制,调动员工的积极性,提高企业的劳动生产率,增加企业的经济效益进行了分析探讨。     

Frequent mtDNA mutations and its role in gastric carcinogenesis

In order to disclose the relationship between mutations of mitochondrial DNA (mtDNA) and gastric carcinogenesis, we screened the entire mtDNA sequence in 30 cases of human gastric cancer and matched normal tissues by using denaturing high-performance liquid chromatography (DHPLC) and DNA sequencing. Our data showed that high frequency (66.7%, 20/30) of mitochondrial genome mutation occurred in gastric cancer. Among these variants, 17 cases (56.7%, 17/30) were identified to be somatic mutation. High level mutant frequency was found in ND4, ND5 coding genes and D-loop control region, which was 36.7%, 26.7% and 30% respectively. Comparing with complexes Ⅲ, Ⅳ and Ⅴof the electron transport chain, we found that variants appeared to be more frequent in the subunit genes of complexⅠ. Most of mutations were base substitutions (85.4%, 41/48). Our results suggested that mutations of subunit genes encoding complexⅠ, especially ND3, ND4 and ND5 genes, might contribute to human gastric carcinogenesis.     

意识形态、文化批判与人的解放（上）——西方马克思主义美学的时代使命与历史局限性

通过对西方马克思主义美学的时代使命与历史局限性的整理，认为意识形态、文化批判与人的解放仍然是我们理解“当代的精神处境”的重要美学线索。