Synthesis of new 7-aminosterol squalamine analogues with high antimicrobial activities through a stereoselective titanium reductive amination reaction

A series of 7-amino- and polyaminosterol analogues of squalamine and trodusquemine were synthesized involving a new stereoselective titanium reductive amination reaction in high chemical yields of up to 95% in numerous cases. These derivatives were evaluated for their in vitro antimicrobial properties against human pathogens. All the compounds present excellent activities against Gram-positive bacteria exhibiting similar results against Staphylococcus aureus and Streptococcus faecalis with minimum inhibitory concentrations (MICs) varying from 2.5 to 10 μg/mL. Numerous derivatives possess also MICs against Gram-negative Escherichia coli bacteria (MICs varying from 2.5 to 10 μg/mL) suggesting that nature of the amino group attached to the sterol moiety plays an important role on the activities of such products.     

各向异性材料中共线刚性线夹杂的纵向剪切问题

本文研究各向异性材料中共线刚性线夹杂，（有时称作“硬裂纹”或“反裂纹”问题）的纵向剪切问题。利用复变函数方法，提出了一般问题的公式和某些实际重要问题的封闭形式解，考察了刚性线端点附近的应力分布．从本文解答的特殊情形，可以直接导出各向同性材料相应问题的公式和结果，包括某些已有的结果￣［７］．     

三元酸易溶酸式盐溶液酸碱度的计算

对三元酸易溶酸式盐溶液(铵盐除外)中H^ 离子浓度的计算公式及公式的应用进行讨论。     

降低工业锅炉初始排尘浓度的对策

通过工业锅炉试验，分析研究了锅炉燃烧方式、煤种、锅炉负荷、过剩空气系数及运行操作等几种对工业锅炉初始排尘浓度有重要影响的因素，并有针对性地提出了一些能有效降低工业锅炉初始排尘浓度的方法和措施。     

The Fundamental Experiments of Red Tide Chemical Forecast

Many food algae and red tide algae were cultivated in the f/2 medium, and the nitric oxide (NO) concentration of the medium and the cell density were determined. The experiments on algae were conducted when different concentrations of NO were added into the medium using two methods. The results show that low concentrations of NO were self-produced by marine algae during the exponential growth period and were about nmol/L level. But at the end of the period, i.e., 2 or 3 days before the cell density reaches the maximum, an NO peak appeared, with the NO concentration reaching 10 nmol/L. The NO threshold concentration exists according to the influence of exogenous NO on the marine phytoplankton growth. One type is the threshold concentration that can promote algae growth, and its value is between 10 and 1 nmol level, or even lower. The other type can inhibit the phytoplankton growth, which is about μmol level or higher. The results indicate that red tide algae are far more sensitive to NO than are food algae. The fundamental experimental outcome above may provide a new clue for red tide chemical forecast by inspecting the NO change.     

细菌芽孢染色方法的改进研究

本文对Schaeffer与Fulton染色方法进行了改进,提出了合理的染液浓度和合理的染色时间。     

Stress concentration around a circular hole in a transversely isotropic spherical shell

Analytical expressions for the stresses near a circular hole in a transversely isotropic shallow spherical shell under uniform pressure are derived. The form of the solution depends on the range of change in the compliance to transverse shear. The influence of the relative radius of the hole and the compliance to transverse shear on the stress concentration is analyzed.__________Translated from Prikladnaya Mekhanika, Vol. 40, No. 12, pp. 99–106, December 2004.     

Reagent concentration effects in the REM resin solid phase synthesis of tertiary amines

The use of reagent concentration has resulted in increased rates for all stages of the REM resin synthesis of tertiary amines. These increases in rate translate into faster reaction times, higher yields and lower reagent consumption. Of the methods examined, the most successful was the use of perfluorous solvents, either alone or with a small amount of organic co-solvent.     

用光学差分吸收光谱监测大气中污染气体浓度

在实验室内模拟测量了实际大气中污染气体的差分吸收光谱 (DOAS) .本文在介绍差分吸收光谱技术同时 ,分析计算了污染气体的浓度 .实验设计中被测气体为大气中的 2种主要污染气体 :工业锅炉的主要排放物SO2 和机动车尾气的主要成分NO .用氘灯作为光源测量其在紫外波段的特征吸收 ,并通过光纤束连接光栅光谱仪 ,由计算机自动采集和处理数据 .