Interaction of liposomes with silica nanocapsules: from lipid bilayer coating to multi-liposomal composites

A new delivery system has been developed that combines liposomes and silica nanocapsules. It was found that in the presence of cationic unilamellar liposomes, silica nanocapsules are instantly coated with a lipid bilayer. In contrast, cationic stealth liposomes modified with polyethylene glycol can adsorb on the surface of silica to form multi-liposomal composites in which the liposomes remain intact.     

铁路集装箱空箱动态优化调度研究

本文在分析铁路集装箱空箱调运存在问题的基础上,运用多目标规划模型,以运输成本最小和主要集装箱优先调运为目标,建立铁路集装箱空箱调运最优化模型,并通过实例检验模型的优化效果,以降低运营成本、提高集装箱使用效率。     

基于遗传算法与贪婪策略的多港口集装箱配载研究

在物流运输行业中,集装箱运输已经成为我国长江沿岸各大港口的主要运输业务。集装箱的处理流程,尤其是集装箱的配载过程直接影响着班轮的运输效率,配载方案的制定对班轮运输起着至关重要的作用。本文针对多港口集装箱船的配载情况,利用CPLEX对该线性规划问题进行求解,并设计遗传算法和贪婪算法对长江沿岸多港口集装箱船配载情形进行对比。通过仿真实验,在小规模时遗传算法与CPLEX求解的精确解相同,验证了遗传算法的有效性。并且在大规模运输情形下,遗传算法得出的结果明显优于贪婪策略,进一步说明了遗传算法是行之有效的。得出的解决方案降低了班轮公司的运输成本,提高了港口的工作效率,对我国长江沿岸港口集装箱配载计划的制定具有一定的指导作用。     

预倒出口箱区的多场桥调度优化

在集装箱出口箱区堆场的实际作业中,常将待提箱提前翻倒至一空闲箱区,使其装船前以船舶配载图的倒序堆垛,以提高装船效率。为提高初始出口箱区的预翻作业效率,针对该箱区的多场桥调度优化问题进行研究。以实施预翻作业的某一出口箱区为研究对象,在船舶配载图已知的前提下,考虑作业场桥间保持安全距离且不可跨越的条件,兼顾满足经验翻箱规则等现实约束,侧重作业过程中实时翻箱,构建了以场桥作业总行走时间最小为优化目标的线性规划模型,并设计了分支定价算法。在算例实验中,通过与非实时预翻箱方案、FCFS方案以及下界进行对比,验证了模型及算法的有效性,可为集装箱码头出口箱堆场的场桥调度提供参考。     

不确定箱量下内河集装箱班轮航线动态配载决策

内河集装箱班轮运输中海关抽检可导致外贸箱箱量不断发生变化,班轮航线配载需要动态决策。基于滚动调度策略,将当前港口的配载决策按随机事件划分为多个阶段,以最小化班轮堆栈占用数量和相邻阶段间配载计划偏差为目标,构建单港口单阶段的配载决策模型,进而滚动实现班轮航线动态配载决策。基于大邻域搜索思想设计一种包含整数规划、破坏器与修复器的精确启发式算法,实现港口多阶段滚动配载。基于真实场景的算例研究表明,在优化堆栈占用数量方面,模型与算法之间差异不大,但在考虑相邻阶段间配载计划偏差时,算法的求解结果要优于模型。因此,模型与算法可用来辅助实现不确定箱量下内河集装箱班轮航线动态配载决策,且算法表现更优,可实现配载计划对不确定箱量的鲁棒吸收。     

Corrosion behavior of high-level waste container materials Ti and Ti–Pd alloy under long-term gamma irradiation in Beishan groundwater

Titanium and titanium–palladium alloys are important potential materials for nuclear waste container, which will endure both intense γ-irradiation and groundwater erosion. Therefore, it is very important to investigate the corrosion behavior of the container materials. In this research, the cumulative dose effect of TA8-1 type titanium–palladium alloy(TA8-1) and TA2-type pure titanium(TA2) under γ-irradiation was studied based on the geological disposal of nuclear wastes. The irradiation experiments were performed at room temperature using60 Co gamma sources with a 5.0-k Gy·h-1 intensity for 40, 80 or 160 days, respectively. The p H value and conductivity of Beishan groundwater were investigated.The results showed that the p H value changed from alkaline(8.22) to acidic(2.46 for TA8-1 and 2.44 for TA2), while the un-irradiated solution remained alkaline(8.17 for TA8-1 and 8.20 for TA2) after 160 days. With the increase of irradiation dose, the conductivity increases rapidly and then tends to become stable, which indicates that the titanium dioxide corrosion layer formed on the surface of the sample surface effectively prevents further corrosion. Meanwhile, XRD and SEM–EDS analysis results show that the main components of corrosion products are Ti O_2 and Ti O. The titanium on the surface of the sample is oxidized, resulting in slight uneven local corrosion. The results show that TA8-1 and TA2 are suitable to be used as candidate materials for high-level waste(HLW) disposal containers due to their excellent performance under long-term and high-dose irradiation corrosion.     

班轮航线设计与空箱调运研究:箱种代用

在考虑多类型集装箱的情况下,本文建立了一个班轮航线设计与空箱调运问题的混合整数线性规划模型,通过假设多类型空集装箱之间可以箱种代用,从而大大减少了空箱的调运量,最后应用CPLEX软件进行了求解。实例研究结果表明,通过箱种代用的手段,可以有效地降低班轮公司的运输成本。     

考虑转移策略的物料配送和空箱回收集成优化

为了降低飞机移动装配线物料供给成本,构建了考虑转移策略的物料配送和空箱回收集成决策模型并设计了求解算法。在配送和回收任务调度的基础上引入了转移任务和线边物料存放的决策,以最小化小车出行成本为目标建立了数学模型并设计了一种以混沌差分进化算法为框架的双层迭代算法。算法上层对配送物料的分批进行搜索,综合考虑小车装载能力和线边空间约束,通过启发式算法对配送小车的发车时间和线边存储位置进行决策,结合转移小车的线边循环运作方式,设计了修复算子对调度和存储方案进行再优化;算法下层对无法即时装载的空箱组批进行搜索,使用转移调度算法进行解码。通过数值实验验证了该模型和算法的有效性。     

圆柱形容器内液体横向晃动的有限元法求解

提出了用变分有限元方法计算容器内液体晃动谐振频率的方法和步骤 ,这种方法可适用于各种形状复杂的容器内液体晃动问题 ,其正确性已经得到验证。按照这一方法计算了卧式圆柱形容器内液体的横向晃动问题 ,并对相关结果进行了总结 ,得出了该类型容器内液体晃动的一般规律。     

Research on Container Behaviors Protocol

With the development of middleware technology, there are some new features to be adopted on demand in middleware platform based on container component. Aiming at the adaptation of middleware platform, from the nature of component container, this paper begins with behaviors features of EJB （Enterprise Java Bean） container, extracts general behaviors protocol of container, and defines its formal behaviors specification. In the end, the interactive relationship of components is described by WRIGHT language, and the configuration of whole system is shown. The method proposed in this paper mines the hidden features of framework of component container, and applies to refactor middleware platform in reflection and aspect-oriented programming technology.