Cyclic sample pooling using two‐dimensional liquid chromatography system enhances coverage in shotgun proteomics

We report a cyclic sample pooling technique devised in two‐dimensional liquid chromatography–electrospray ionization mass spectrometry (LC‐ESI‐MS) shotgun proteomics that renders deeper proteome coverage; we combined low pH reversed‐phase (RP) LC in trifluoroacetic acid in the first dimension, followed by cyclic sample pooling of the eluate and low‐pH RP‐LC in formic acid in the second dimension. The new protocol has a significantly higher resolving power suitable for LC‐ESI‐MS/MS shotgun proteomics. Copyright © 2013 John Wiley & Sons, Ltd.     

Modeling and character analyzing of multiple fractional-order memcapacitors in parallel connection

Recently,the memory elements-based circuits have been addressed frequently in the nonlinear circuit theory due to their unique behaviors.Thus,the modeling and characterizing of the mem-elements become essential.In this paper,the analysis of the multiple fractional-order voltage-controlled memcapacitors model in parallel connection is studied.Firstly,two fractional-order memcapacitors are connected in parallel,the equivalent model is derived,and the characteristic of the equivalent memcapacitor is analyzed in positive or negative connection.Then a new understanding manner according to different rate factor K and fractional orderαis derived to explain the equivalent modeling structure conveniently.Additionally,the negative order appears,which is a consequence of the combination of memcapacitors in different directions.Meanwhile,the equivalent parallel memcapacitance has been drawn to determine that multiple fractional-order memcapacitors could be calculated as one composite memcapacitor.Thus,an arbitrary fractional-order equivalent memcapacitor could be constructed by multiple fractional-order memcapacitors.     

创新教育对传统教育的继承与革新试析

创新教育是以培养学生创新精神和创新能力为基本价值取向的教育。它源于时代的发展，但又非孤立存在。它以传统教育为基础——继承传统教育几千年来的教育理论，实践的精华，又和传统教育相对立——扬弃传统教育中陈旧、单一，定势的观念，并在对传统教育的继承．扬弃中发展，创立新的教育模式，以使教育更加适应知识经济时代飞速发展的需要。     

可纠错pooling设计的一个构作

一个非时序性群试(NGT)算法在DNA筛选等领域都有重要应用,而NGT算法的一个数学模型是d-disjunct矩阵.通过Bd(δ**(n,d,k))的Hamming距离构作一个d-disjunct矩阵,其中δ**(n,d,k)是在δ(n,d,k)的基础上加上δc(n,α,k)构成的,1≤α≤m+1且α∈Z;证明了所构作的矩阵是可纠正1个错误、检测2个错误的d-disjunct矩阵.     

论大中小学德育有效衔接的概念与标准

构建大中小学有效衔接的德育体系,是《国家中长期教育改革和发展规划纲要（2010-2020年）》明确提出的战略任务。大中小学德育衔接存在纵向衔接和横向贯通两个维度,与大中小学德育一体化、整体构建大中小学德育体系等概念既有联系又有区别。大中小学德育衔接是否有效,应以是否形成了一个整体的德育体系和网络为形式标准,以是否很好地实现了德育目标、对实现培育＂四有＂新人是否产生合力与合力大小为实质标准。     

Metric inequalities for routings on direct connections with application to line planning

We consider multi-commodity flow problems in which capacities are installed on paths. In this setting, it is often important to distinguish between flows on direct connection routes, using single paths, and flows that include path switching. We derive a feasibility condition for path capacities supporting such direct connection flows similar to the well-known feasibility condition for arc capacities in ordinary multi-commodity flows. The condition can be expressed in terms of a class of metric inequalities for routings on direct connections. We illustrate the concept on the example of the line planning problem in public transport and present an application to large-scale real-world problems.     

高中化学与大学无机化学教材知识点的衔接研究*

作为化学教育专业的必修课程,无机化学起到了奠定师范生化学理论基础的重要作用。在衔接高中化学知识的前提下,开展大学无机化学教学有助于构建完整的化学知识教学体系、调动师范生学习的积极性,实现高中到大学无机化学课程学习的顺利过渡。笔者在教学实践、教育实习指导及调研的基础上,以人教版高中化学、北师大版《无机化学》教材内容为例,从教与学的角度探讨了高中化学和大学无机化学教材知识点的衔接情况,形成了部分经验积累和教学建议,为师范类专业认证背景下的无机化学课程教学提供借鉴和参考。     

三桁钢桁梁桥横桥向内力调整方法及影响参数

针对多主桁钢桥结构成桥状态中边桁受力不均衡的情况,结合三桁刚性悬索加劲钢桁梁桥--东江大桥,介绍了通过预设横向预拱度来横向调整三片主桁构件内力这一新技术,并分析了其调整原理.为了验证此技术的有效性,应用有限元程序,建立实桥三维有限元模型,对比了内力调整前后中边桁控制弦杆与加劲弦的轴力与不均衡系数,分析了横梁竖向抗弯刚度...     

统计流形在切丛上提升的等积仿射结构

具有等积仿射结构的统计流形在贝叶斯统计理论中有着重要应用,主要讨论统计流形及其切丛上的等积仿射结构,得到了统计流形的无挠仿射联络和其在切丛上提升的仿射联络的等积仿射性是一致的.     

"批"概念下的继电控制系统功能仿真

提出模拟继电控制系统中事件的时序的“批”概念,再根据事件传播特性给出了事件模拟算法。利用深度广度结合遍历方式及Tarjan拓扑块划分算法获取线路中元件的电气拓扑——连接矩阵。基于以上两点,再利用继电控制线路图上表达出的驱动元件与开关之间的关系。实现了对继电控制系统的功能仿真。