Turbulence Closure with a Topography-parameter-free Single Equation Model

A new topography-parameter-free turbulence closure, based on a transport equation for the pseudo eddy viscosity, is described. The model is tested against experimental data of several flow cases across the Mach number range and compared to Menter's single equation model and to the Spalart-Allmaras model. The main conclusion is that the new closure outperforms the other two models in both low and high speed flows.     

Waspaloy镍基合金高温流变应力及其本构模型构建

针对涡轮发动机涡轮叶片复杂应力状态下的时效变形问题,以涡轮叶片材料Waspaloy镍基合金为研究对象,开展Waspaloy镍基合金时效处理,完成时效态Waspaloy镍基合金600℃、700℃和750℃准静态高温力学拉伸试验,利用Ludwik和Hollomon经验公式预测Waspaloy镍基合金高温塑性段流变应力,引入平均误差（Er）和均方根误差（RMSE）评价流变应力的预测准确度。结果表明,时效处理后合金的硬度得到有效提升,而其塑性性能有所降低。Waspaloy镍基合金的抗拉强度和延伸率在600℃~750℃区间范围内与加载温度呈负相关关系。Ludwik模型较Hollomon模型有更高的流变应力预测精度,而在高温高应变区域Ludwik模型预测流变应力仍存在较大误差。在Ludwik模型的基础上引入指数项,修正后的Ludwik模型能更好地预测Waspaloy镍基合金高温塑性段的流变应力。     

模糊交货期Flow Shop调度文化进化算法研究

基于文化算法及文化进化思想设计了的文化进化算法,通过上层文化空间的经验知识指导下层个体进化搜索的方向及步长,通过模拟人类社会文化进化的机制实现文化空间的进化与更新,最后将算法应用到模糊Flow Shop问题的求解,用Matlab编程仿真测试.结果表明,此算法解决生产调度优化问题是可行的,而且其搜索性能优于简单遗传算法及模拟退火算法.     

Determination of nicotinamide by stopped-flow injection method in pharmaceutical formulations

A simple stopped-flow injection system with spectrophotometric detection was proposed for the determination of nicotinamide (NAM) in pharmaceutical formulations. In this system cyanogen chloride formed from the combination of an acidic KSCN with the NaClO streams reacts with injected NAM to form glutaconic aldehyde. Then the product of these three components was coupled with another buffered (pH 3.5) stream of barbituric acid and directed towards the detector. A 45 s after sample injection the pump was stopped for 130 s. During this time the reactants in the flow cell were provided with the required temperature (40 °C) by placing the cell in a home made cell jacket to increase the yield of the polymethine dye product. Eventually, the absorbance of the formed pink color dye was monitored spectrophotometrically at 560 nm and NAM in the concentration range of 1.0–25.0 μg/mL (R = 0.9974 and D.L = 0.5 μg/mL) was determined. The results obtained by this method were compared statistically and agree with those obtained by the method described in the British Pharmacopoeia.     

Flow injection analysis simulations and diffusion coefficient determination by stochastic and deterministic optimization methods

Stochastic and deterministic simulations of dispersion in cylindrical channels on the Poiseuille flow have been presented. The random walk (stochastic) and the uniform dispersion (deterministic) models have been used for computations of flow injection analysis responses. These methods coupled with the genetic algorithm and the Levenberg–Marquardt optimization methods, respectively, have been applied for determination of diffusion coefficients. The diffusion coefficients of fluorescein sodium, potassium hexacyanoferrate and potassium dichromate have been determined by means of the presented methods and FIA responses that are available in literature. The best-fit results agree with each other and with experimental data thus validating both presented approaches.     

Ammonium chloride salting out extraction/cleanup for trace-level quantitative analysis in food and biological matrices by flow injection tandem mass spectrometry

A sample extraction and purification procedure that uses ammonium-salt-induced acetonitrile/water phase separation was developed and demonstrated to be compatible with the recently reported method for pesticide residue analysis based on fast extraction and dilution flow injection mass spectrometry (FED-FI-MS). The ammonium salts evaluated were chloride, acetate, formate, carbonate, and sulfate. A mixture of NaCl and MgSO₄, salts used in the well-known QuEChERS method, was also tested for comparison. With thermal decomposition/evaporation temperature of <350 °C, ammonium salts resulted in negligible ion source residual under typical electrospray conditions, leading to consistent method performance and less instrument cleaning. Although all ammonium salts tested induced acetonitrile/water phase separation, NH₄Cl yielded the best performance, thus it was the preferred salting out agent. The NH₄Cl salting out method was successfully coupled with FI/MS/MS and tested for fourteen pesticide active ingredients: chlorantraniliprole, cyantraniliprole, chlorimuron ethyl, oxamyl, methomyl, sulfometuron methyl, chlorsulfuron, triflusulfuron methyl, azimsulfuron, flupyrsulfuron methyl, aminocyclopyrachlor, aminocyclopyrachlor methyl, diuron and hexazinone. A validation study was conducted with nine complex matrices: sorghum, rice, grapefruit, canola, milk, eggs, beef, urine and blood plasma. The method is applicable to all analytes, except aminocyclopyrachlor. The method was deemed appropriate for quantitative analysis in 114 out of 126 analyte/matrix cases tested (applicability rate = 0.90). The NH₄Cl salting out extraction/cleanup allowed expansion of FI/MS/MS for analysis in food of plant and animal origin, and body fluids with increased ruggedness and sensitivity, while maintaining high-throughput (run time = 30 s/sample). Limits of quantitation (LOQs) of 0.01 mg kg⁻¹ (ppm), the ‘well-accepted standard’ in pesticide residue analysis, were achieved in >80% of cases tested; while limits of detection (LODs) were typically in the range of 0.001–0.01 mg kg⁻¹ (ppm). A comparison to a well-established HPLC/MS/MS method was also conducted, yielding comparable results, thus confirming the suitability of NH₄Cl salting out FI/MS/MS for pesticide residue analysis.     

Determination of Total Chromium in Biological Samples by Automated Reagent Injection Chemiluminescence Analysis

A sensitive method for the determination of total chromium in real samples by flow injection–chemiluminescence (FI–CL) analysis was proposed. It was found that the CL intensity from luminol–lysozyme reaction could be markedly quenched, and the decrease of CL intensity was linear with the logarithm of Cr(III) concentrations over the range of 5.0 to 4000 pg mL^?1 with a detection limit of 2.0 pg mL^?1 (3σ) and relative standard deviations (RSDs) of 3.0, 2.6, and 2.0% for 10, 100, and 1000 pg mL^?1 Cr(III) (n = 7), respectively. At a flow rate of 2.0 mL min^?1, the whole process including sampling and washing could be accomplished within 36 s. The proposed CL method was successfully applied to the determination of total chromium in pharmaceutical capsules, a dietary supplement, and spiked human serum samples, with recoveries from 92.2 to 108.4% and RSDs of less than 4.0%. Using the homemade FI–CL model, the binding constant (K = 4.38 × 10⁶ L mol^?1) and the binding sites (n ≈ 1) of Cr(III) to lysozyme were given.     

A simulation method of aircraft plumes for real-time imaging

Real-time infrared simulation technology can provide a large number of infrared images under different conditions to support the design, test and evaluation of a system having infrared imaging equipment with very low costs. By synthesizing heat transfer, infrared physics, fluid mechanics and computer graphics, a real-time infrared simulation method is proposed based on the method of characteristics to predict the infrared feature of aircraft plumes, which tries to obtain a good balance between simulation precision and computation efficiency. The temperature and pressure distribution in the under-expansion status can be rapidly solved with dynamically changing flight statuses and engine working states. And a modified C–G (Curtis–Godson) spectral band model that combines the plume streamlines with the conventional C–G spectral band model was implemented to calculate the non-uniformly distributed radiation parameters inside a plume field. The simulation result was analyzed and compared with the CFD++, which validates the credibility and efficiency of the proposed simulation method.     

Complex three-dimensional microparticles from microfluidic lithography

Complex 3D microparticle, as an emerging and attractive field, has attracted more and more attention due to its versatile morphologies and broad range of applications. In this review, we provide an overall recent progress in 3D microparticles fabricated by microfluidic lithography. This review will focus on the synthesis mechanisms, synthesis process, the resultant 3D microparticles, and their applications. Finally, we will look into the future trends in complex 3D microparticles. This review will be beneficial for researchers in numerous fields, including functional materials, sensors, encryption, and biomedical engineering.     

十字旋阀塔板的流体力学性能

在1 000 mm的圆塔内,采用空气-水系统对十字旋阀塔板的流体力学性能进行了测试,考察了液流强度、出口堰高、开孔率等因素对塔板压降、雾沫夹带及泄漏性能的影响。结果表明:在小液流强度下,十字旋阀塔板上气体分散均匀,泡沫层高度稳定,气液接触充分,具有较好的流体力学性能和优势。