双联光声传感器和差分池在液体光声检测中的应用

利用双联传感器得到光声信号的叠加作用,可提高光声检测灵敏度或扣除溶液背景吸收。以亚硝基R盐测定钴为例,得到最低检测浓度为0.3ng/mL,相当于4.25×10~(-5)的吸收。     

Estimation of the sound pressure field of a baffled uniform elliptically shaped transducer

In this paper an alternative approach to estimate the sound field of an elliptically shaped transducer in an infinite baffle is described. The method is based on a singular value decomposition of a propagating matrix which is computed through a division of the vibrating surface into a finite number of small circular piston sources flush-mounted on the elliptical surface. This decomposition is combined with the volume velocity vector on the discretized surface to obtain the sound pressure field. Numerical examples for both on-axis sound pressure and directivity are presented for the uniform elliptical piston transducer and they are in good agreement with the results given by other methods.     

激光荧光肺癌诊断图象处理系统滤光片的研制

本文论述用于激光荧光肺癌诊断图象处理系统滤光片的膜系设计,制备这套滤光片所采取的工艺措施,最后给出研制的结果。     

Reusable conductimetric array of interdigitated microelectrodes for the readout of low-density microarrays

Low-density protein microarrays are emerging tools in diagnostics whose deployment could be primarily limited by the cost of fluorescence detection schemes. This paper describes an electrical readout system of microarrays comprising an array of gold interdigitated microelectrodes and an array of polydimethylsiloxane microwells, which enabled multiplexed detection of up to thirty six biological events on the same substrate. Similarly to fluorescent readout counterparts, the microarray can be developed on disposable glass slide substrates. However, unlike them, the presented approach is compact and requires a simple and inexpensive instrumentation. The system makes use of urease labeled affinity reagents for developing the microarrays and is based on detection of conductivity changes taking place when ionic species are generated in solution due to the catalytic hydrolysis of urea. The use of a polydimethylsiloxane microwell array facilitates the positioning of the measurement solution on every spot of the microarray. Also, it ensures the liquid tightness and isolation from the surrounding ones during the microarray readout process, thereby avoiding evaporation and chemical cross-talk effects that were shown to affect the sensitivity and reliability of the system. The performance of the system is demonstrated by carrying out the readout of a microarray for boldenone anabolic androgenic steroid hormone. Analytical results are comparable to those obtained by fluorescent scanner detection approaches. The estimated detection limit is 4.0 ng mL⁻¹, this being below the threshold value set by the World Anti-Doping Agency and the European Community.     

变频调速器在棉纺厂自动换气调温系统中的应用

本文叙述了棉纺厂自动调温系统的硬件组成和工作原理，重点介绍了变频调速器的选择和控制，讨论了使用后的效果。     

Reflector-based phase calibration of ultrasound transducers

Recently, the measurement of phase transfer functions (PTFs) of piezoelectric transducers has received more attention. These PTFs are useful for e.g. coding and interference based imaging methods, and ultrasound contrast microbubble research. Several optical and acoustic methods to measure a transducer’s PTF have been reported in literature. The optical methods require a setup to which not all ultrasound laboratories have access to. The acoustic methods require accurate distance and acoustic wave speed measurements. A small error in these leads to a large error in phase, e.g. an accuracy of 0.1% on an axial distance of 10 cm leads to an uncertainty in the PTF measurement of ±97° at 4 MHz. In this paper we present an acoustic pulse-echo method to measure the PTF of a transducer, which is based on linear wave propagation and only requires an estimate of the wave travel distance and the acoustic wave speed. In our method the transducer is excited by a monofrequency sine burst with a rectangular envelope. The transducer initially vibrates at resonance (transient regime) prior to the forcing frequency response (steady state regime). The PTF value of the system is the difference between the phases deduced from the transient and the steady state regimes. Good agreement, to within 7°, was obtained between KLM simulations and measurements on two transducers in a 1-8 MHz frequency range. The reproducibility of the method was ±10°, with a systematic error of 2° at 1 MHz increasing to 16° at 8 MHz. This work demonstrates that the PTF of a transducer can be measured in a simple laboratory setting.     

温控杨氏模量的研究

本文利用温控杨氏模量测量仪对不同材料的杨氏模量随温度的变化规律进行了研究,发现随温度的升高杨氏模量有下降的趋势。对不同直径的不锈钢金属棒的杨氏模量进行研究后发现,在同一温度点上杨氏模量减小。     

The development of a shock-tube based characterization technique for air-coupled ultrasonic probes

The present paper proposes a new characterization technique for air-coupled ultrasound probes. The technique is based on a shock tube to generate a controlled pressure wave to calibrate transducers within their operating frequency range. The aim is to generate a high frequency pressure wave (at least up to 200 kHz) with the low energy levels typical of commonly used air-coupled ultrasound probes. A dedicated shock-tube has been designed and tested to assess calibration performances. The sensor transfer function has been measured by using a pressure transducer as reference.     

水下应用的电容式微机械超声换能器阵列设计

为提高用于水下成像的电容式微机械超声换能器的指向性,文中用ANSYS力电耦合分析法设计了工作频率为400 k Hz的收发一体传感器的结构参数并完成了实验验证。同时研究了阵列设计方法,分析了电容式微机械超声换能器阵列各参数对指向性的影响,完成了从微小敏感单元到阵列的设计,实现了阵列指向性的优化设计。该阵列为16阵元的线阵,阵元间距为1.925 mm,阵元宽度为1.82 mm。进行了水下指向性测试,实验表明该线阵的-3 dB主瓣宽度为5?,最大旁瓣级为-13.5 dB,对称性好。该设计是实现较远距离的探测,提高成像分辨率的前提。     

泌尿系统治疗用HIFU换能器的设计

高强度聚焦超声技术是‘种将超声能量聚焦于人体深部组织的狭小区域,形成足够高的声强,使组织瞬时在局部产生高温、无创性局部治疗肿瘤的新技术。近年来,泌尿系统疾病发病率迅速上升,尤其是前列腺疾病发病率高,相关的并发症也较多,已成为威胁男性生命健康的重要疾病。本文应用高强度聚焦超声技术,设计了治疗泌尿系统疾病的线阵换能器。仿真结果证明:该换能器的卢场能量集中,声强峰值尖锐,焦点尺十小,聚焦效果好,可以达到有效无损治疗的目的。