A New Synthetic Approach to Elvucitabine

A new synthetic approach to elvucitabine started from L-xylose via the reactions of 10 steps in an overall yield of 20% was developed. The key steps included trimethylsilyl trifluoromethanesulfonate(TMSOTf)-mediated stereocontrolled β-glycosidation and exquisite choice of chloroacetyl group for the protection of hydroxyl groups as well as the corresponding deprotection under notably mild conditions. The structure of elvucitabine, in particular, the stereochemistry thereof, was unambiguously determined by comparison of the physical properties, such as ¹H NMR data and the specific rotation, of the synthesized sample with those reported.     

融合合成孔径雷达和光学影像的植被覆盖区土壤湿度反演

利用合成孔径雷达(synthetic aperture radar,SAR)卫星可对土壤湿度实现大面积、时间连续的反演.针对此过程中难以消除植被遮挡的问题,提出融合SAR微波数据和光学数据,利用修正水云模型消除植被影响,求解纯粹地表后向散射系数,代入裸土区土壤湿度反演算法进行土壤湿度反演,并在武汉豹澥区域设置实测站点记录实测数据进行比对.结果分析表明,经过植被消除后,实测站点垂直极化后向散射系数平均衰减量与植被覆盖度之间时间序列上相关系数达到0.83;土壤湿度反演值与实测值趋势相关性平均提升0.08,且提升程度与植被覆盖度相关系数也达到0.8以上,表明本算法针对植被覆盖度越大区域反演效果越好.该方法通过SAR影像和光学影像融合反演长时间序列土壤湿度具有良好可信度.     

Country road and field surface profiles acquisition,modelling and synthetic realisation for evaluating fatigue life of agricultural machinery

Fatigue life of agricultural machinery is strongly affected by the surfaces that these machines operate on. In the present paper a sensor-frame was developed to acquire road and field profiles in absolute geo-referenced coordinates. The sensor-frame was validated by measuring discrete trapezoidal bumps with known dimensions resulting in a root mean squared (RMS) error of 6–8 mm. Profiles were acquired from a country road and from a mowed grass field. Using the quarter-car vehicle model, the movement of an agricultural vehicle was simulated for various speeds. The resulted vertical loads were rainflow-counted and the accumulated fatigue pseudo damage was calculated using Palmgren–Miner linear rule. Based on the derived Power Spectrum Density (PSD), the profiles were classified according to ISO 8608 standard. Two methodologies were followed to model and create a number of synthetic realisations for each profile: Direct Spectrum Estimate (DSE) and ISO based modelling. Simulating the produced synthetic profiles with the quarter-car vehicle model, the corresponding pseudo damage was calculated. The accumulated damages from the DSE models were closer to the corresponding ones from the measured profiles. ISO based models could not model the profile irregularities, which proved to contribute the largest part of the accumulated fatigue damage.     

荧光光谱结合支持向量机测定食用色素纯度

采用一种由原点矩法改造所得的特征压缩算法对荧光光谱数据进行预处理,将处理后的数据与加权最小二乘支持向量机(WLS-SVM)算法结合,建立鲁棒回归模型,用以预测实际食用色素粉末的纯度。以亮蓝和胭脂红这2种色素为例论述该方法对实际食用色素粉末纯度的预测效果。首先,利用FLS920荧光光谱仪测量获得两种色素的标准样本和实际样本在最佳激发波长下的荧光发射光谱数据,利用由原点矩法改造所得的特征压缩算法对获取的荧光光谱数据进行压缩和变换,一方面缩短了算法的运算时间,另一方面也提高了模型的预测精度。将预处理后的荧光光谱数据输入加权最小二乘支持向量机中建立浓度预测模型,该模型对亮蓝、胭脂红实际样本溶液给出的预测光谱与它们的实测光谱吻合程度好,半高峰宽区间内的平均决定系数分别为0.662和0.931。所有亮蓝、胭脂红溶液的预测浓度和标称浓度之间具有良好的线性关系,相关系数分别为0.997和0.992。由此通过多项式拟合得到的亮蓝、胭脂红粉末的预测纯度分别为61.0%和72.3%。     

Influence of preliminary ultrasonic treatment upon the steady-state creep of metals of different stacking fault energies

This paper addresses the issue of the ultrasound effects upon the creep deformation of metals with different levels of stacking fault energy. The influence of preliminary ultrasound irradiation time upon the steady state creep rate is considered. Synthetic theory of irrecoverable deformation is taken as a mathematical apparatus. The analytical results show good agreement with experimental data.     

逆合成孔径成像激光雷达实包络成像算法

逆合成孔径激光成像雷达受激光调制技术以及回波相位信息易受大气湍流破坏的限制,采用常规的相位相干积累类方法得到目标二维高分辨图像很困难.针对这一情况,提出了一种基于逆Radon变换的实包络成像算法.利用回波距离脉冲压缩后的实包络信息,实现方位向的非相干积累,最终得到二维高分辨图像.通过该算法,成像系统可以使用非相干激光信号,在脉冲重复频率较低且存在大气湍流的情况下,也可以获得高质量的成像结果.仿真实验验证了此算法的有效性和优越性.     

星载可见光相机成像仿真建模研究

针对星载可见光相机成像模拟在逼真度和灵活性方面的综合仿真应用需求,研究并提出了一种以三维场景为基础,以光线追踪技术为主要渲染核心,综合考虑卫星轨道和姿态、光照条件、物体光谱特性和周边环境、大气传输、遥感器成像性能等影响因素的全光路成像模拟技术的仿真模型.文中首先从完备性及可扩展性的角度尝试建立了成像仿真系统的综合模型框架,对整个成像链中的各个重要环节进行分层及模块化,并结合目前现有三维技术、光线追踪技术、传感器仿真技术的特点设计各模块之间的调用及接口关系,使其能在较好利用现有计算模型的同时能够对新的算法模型实现有效兼容.随后讨论了模型目前使用的镜头前辐亮度计算模块、光线路径计算模块和传感器效果仿真模块,并针对简单空间探测场景用C++编程语言实现了系统框架和关键模型,生成模拟图像,结果证明该模型在深空光照及大气效果方面有较好的表现,具备较高的仿真度和良好的适应性、扩展性,能够有效支撑卫星光学成像系统的指标论证、算法评估以及效能预估等应用.     

Monolithic columns with optimized pore structure for molecular size-based separations of synthetic polymers

Monolithic capillary columns based on divinylbenzene were synthesized using different alcanols as porogens. Prepared columns were tested in separation of polystyrene standards according to their molar mass (MM) and were characterized by corresponding calibration graphs. It was demonstrated that a decrease of alcanol chain length from dodecanol to octanol resulted in a decrease of column permeability and in an improved column ability to separate polystyrene standards. In contrast, removing a good solvent from porogen mixture results in an increase of column permeability and in a decrease of column performance toward polystyrene standards. Optimized synthetic conditions included porogen composed of nonanol and toluene or mesytilene, and the column prepared with this porogen was capable of separating a mixture of 14 polystyrene standards with MM ranged from several millions to oligomers.     

液相色谱-串联质谱法测定食品中合成色素

提出了液相色谱-串联质谱法测定食品中8种合成色素柠檬黄、苋菜红、胭脂红、日落黄、诱惑红、亮蓝、赤藓红和偶氮玉红的含量。固体(半固体)样品经乙醇-氨水-水(70+1+29)溶液溶解,所得滤液烘干后用水溶解,经Waters Atlantis dC18色谱柱(2.1 mm×150 mm,5μm)分离,用甲醇和10 mmol.L-1乙酸铵溶液以不同体积比混合进行梯度洗脱,采用电喷雾正离子模式串联质谱检测。8种合成色素的质量浓度均在50μg.L-1以内与其峰面积呈线性关系,检出限(3S/N)在0.003～0.020 mg.kg-1之间。方法应用于食品样品中8种合成色素的测定,回收率在83.0%～112.0%之间,测定值的相对标准偏差(n=6)均小于5%。     

Determination of ethylenediaminetetraacetic acid in sea water by solid-phase extraction and high-performance liquid chromatography

The chelating agent EDTA is widely used, and as a result is showing up widely in the aquatic environment. Here we describe a preconcentration procedure for measuring EDTA concentration in sea water samples by HPLC. The procedure consists of forming an Fe(III) complex followed by solid-phase extraction using an activated carbon cartridge. After the preconcentration, EDTA was quantified by HPLC with ultraviolet detection (260 nm). The enrichment permitted the determination of EDTA at concentrations as low as 1 nM. Good recoveries were obtained for both brackish and full-strength sea water with high repeatability (RSD < 6%). The method was applied to sea water samples taken from near the mouth of the Oyabe River in Japan.