基于GPRS无线数据采集和传输终端的设计

介绍了一种基于GPRS技术及SoC片上系统C8051F060实现的无线数据采集和传输终端系统,采集的数据通过GPRS无线通讯网络发送至数据中心.研究分析了系统的硬件结构设计、操作系统应用、TCP/IP协议栈实现等核心技术.该系统具有运行稳定、传输及时高效等特点,在工业控制领域可被广泛应用.     

Molecular Analysis and Conformational Dynamics of Human MC4R Disease-Causing Mutations

Obesity is a chronic disease with increasing cases among children and adolescents. Melanocortin 4 receptor (MC4R) is a G protein-coupled transporter involved in solute transport, enabling it to maintain cellular homeostasis. MC4R mutations are associated with early-onset severe obesity, and the identification of potential pathological variants is crucial for the clinical management of patients with obesity. A number of mutations have been reported in MC4R that are responsible for causing obesity and related complications. Delineating these mutations and analyzing their effect on MC4R’s structure will help in the clinical intervention of the disease condition as well as designing potential drugs against it. Sequence-based pathogenicity and structure-based protein stability analyses were conducted on naturally occurring variants. We used computational tools to analyze the conservation of these mutations on MC4R’s structure to map the structural variations. Detailed structural analyses were carried out for the active site mutations (i.e., D122N, D126Y, and S188L) and their influence on the binding of calcium and the agonist or antagonist. We performed molecular dynamics (MD) simulations of the wild-type and selected mutations to delineate the conformational changes, which provided us with possible reasons for MC4R’s instability in these mutations. This study provides insight into the potential direction toward understanding the molecular basis of MC4R dysfunction in disease progression and obesity.     

一种结合空时编码的MC-DS-CDMA方法

空时编码技术通过空间和时间分集接收能有效增加信道容量。多载波直接扩频序列码分多址 (DS- CDMA)技术将一个宽带频率选择性信道划分成多个频率非选择性子载波 ,在子载波上并行发送信号 ,能有效地抑制信道的多径衰落。该文将空时编码技术和多载波通信相结合 ,设计了一种新颖的基于多发射天线的 MC- DS- CDMA方法。与传统的方法相比 ,该方法有效地利用了空间分集技术 ,从而降低数据传输的错误 ,提高信道容量。仿真实验结果表明 ,这种新系统的性能优于传统的 MC- DS- CDMA方法。     

计算植被生态学及其解决方案

初步提出了计算植被生态学这一新的生态学分支学科及其面向算法的计算机技术支持新方案,认为数据结构和算法研究是其核心研究内容之一.提出了按数学方法和计算机技术在生态学中的作用对现代生态学分支学科进行分类的MC划分方法,该方法能反映计算植被生态学的学科地位,其分类效果优于景观生态学时空尺度划分方法和应用生态学应用性-基础性划分方法.按照数据采集、存贮、分析和显示的流程分析了计算植被生态学的研究方法、研究内容及其主要支撑技术,认为计算植被生态学的建立有助于产生可被重复利用的生态学模型和算法,实现植被研究的计算机化,为区域可持续发展服务.     

数控加工中心的选用策略

针对加工中心的特点和企业发展对加工中心的要求,分析了企业在引进加工中心时存在的问题。提出了正确选择加工中心的策略和原则。阐述了加工中心选择的主要策略内容和关键部件选择的方法与要求。加工中心的合理选择可以保证企业投资决策的正确性,并为企业带来可观的经济效益。