8 种杀菌剂防治马铃薯晚疫病的田间药效试验

8种不同杀菌剂对马铃薯晚疫病田间药效试验结果表明,50%施得益WP、60%双工福玛WP、25%瑞凡SC、80%大生M-45WP、30%富民一号SC 5种杀菌剂对马铃薯晚疫病的防效均在70%以上,以50%施得益WP防治效果最好,防效为87.65%。施用50%施得益WP和60%双工福玛WP后增产率极显著,挽回损失55.54%和47.44%。     

Pentafluorocyclopropanation of (Hetero)arenes Using Sulfonium Salts: Applications in Late-Stage Functionalization

The evaluation of the pentafluorocyclopropyl group as a chemotype in crop protection and medicinal chemistry has been hampered in the past by the lack of suitable methodologies that enable the practical incorporation of this moiety into advanced synthetic intermediates. Herein, we report the gram-scale synthesis of an unprecedented sulfonium salt, 5-(pentafluorocyclopropyl)dibenzothiophenium triflate, and its use as a versatile reagent for the photoinduced C−H pentafluorocyclopropylation of a broad series of non-previously functionalized (hetero)arenes through a radical mediated mechanism. The scope and potential benefits of the protocol developed are further demonstrated by the late-stage introduction of the pentafluorocyclopropyl unit into biologically relevant molecules and widely used pharmaceuticals.