A regular perturbation analytical‐numerical method for the evolution of precancerous lesions caused by the human papillomavirus

A numerical method is developed to analyze the behavior of the evolution of the lesions at the cervical cells caused by the human papillomavirus. The model to be solved consists in a one‐dimensional nonlinear advection–diffusion‐reaction equation. Such equation is approximated by a consistent explicit difference scheme which is based on regular perturbation theory. A constructive procedure for the numerical scheme is given and finally an illustrative example of the evolution of a mild dysplasia is included. © 2014 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 31: 847–855, 2015     

人类基因组研究的伦理问题

目前，人类基因组研究的伦理问题主要集中在基因隐私、基因歧视和基因组多样性等方面．本文系统地阐述了人类基因组研究的伦理问题，为人类基因组研究的方向圈定了界限．     

Radially symmetric weighted extended b-spline model

In this paper, the weighted extended basis splines approach in the finite element method is applied to the electrostatic, electromagnetic wave and bioheat problems for inhomogeneous boundary conditions and radially symmetric structures. This new method, which does not need mesh generation, overcomes some of the drawbacks of using meshes and piecewise-uniform or linear trial functions. Two-dimensional radially symmetric electrostatic and electromagnetic wave equations are evaluated. We also attempt to propose a three-dimensional radially symmetric unexposed human eye model for simulating changes in corneal temperature using these new finite elements in conjunction with linear, quadratic and cubic b-splines. Our findings indicate that weighted extended basis spline solutions improve the standard finite element method. The simulation results which are verified using the values reported in the literature, point out to better efficiency in terms of the accuracy level.     

Recent developments in Dual Resource Constrained (DRC) system research

Real world manufacturing systems are usually constrained by both machine and human resources. Human operators are often the constraining resource and transfer between workstations to process jobs when required. This kind of system is known as a Dual Resource Constrained (DRC) system and presents additional technical challenges which must be considered during planning and scheduling. These technical challenges can be categorised into the five main dimensions of job release mechanisms, job dispatching, worker flexibility, worker assignment and transfer costs. This paper aims to provide an overview of recent developments in DRC research concerned with each of these areas and also discusses some possible approaches to solving the resource scheduling problem in a DRC system. The focus is on materials published after 1995 and up to 2009. Previous reviews on DRC systems are commented on and followed by a review of recent works associated with each of the five dimensions of DRC system research. Advancements made and new methodologies proposed are discussed and future research directions are identified.     

Decision support for the career field selection process at the US Air Force Academy

Each year, the US Air Force Academy graduates nearly 1000 young men and women. To support the decision of which cadets will be classified into which career fields, we describe a linear programming formulation with appealing computational properties that enable it as the core of a decision support tool. We explore methods for measuring and balancing cadets' class standing, Air Force career field requirements, and cadets' career field preferences in the context of this model. Our computational experiments demonstrate the improvement of this method over previous classification approaches, yielding more than 10% increase in the number of cadets assigned to their top career field choice and yielding nearly a 100% reduction in the number of cadets not receiving any of their career field choices. We also explore alternative methods for measuring cadets' career field preferences and demonstrate the positive effect of the new measurement scheme on the overall classification. Because of the short running time of this model, it will serve as a flexible, real-time component of the Academy's classification process.     

考虑资本闲置的多年时滞人力资本投入占用产出模型

人力资本理论强调的是由教育所新增的人力资本对经济增长的决定作用.为了规划与中国经济持续增长相适应的人力资本需求,建立了一个新颖的考虑资本闲置的多年时滞投入占用产出模型.为了考虑人力资本时滞长的特点以及人力资本占用的损耗补偿,在斯通人口投入产出模型和Leontief动态投入产出模型基础上,提出了多年时滞人力资本投入占用产出模型.将LDS模型推广为考虑资本闲置的多年时滞人力资本投入占用产出模型,以便考虑影响教育产出的外生因素,并推导出既适于产出增加也适于产出减少的正解.应用上,预测至2015年的各种教育水平人力资本的总量和部门需求,发现高级人力资本短缺和人才行业结构不合理是经济发展需要解决的重要问题.     

含公共开支的两部门内生经济增长模型

本文研究了一个含公共开支的两部门的内生经济增长模型 ,其生产函数具有最一般的形式 .用于两部分的三要素—物质资本 ,人力资本 ,有效劳动的份额正相关 ,产出用于公共开支的份额与用于生产部门的三要素的份额负相关 ,经济增长极大地依赖于生产弹性 .并给出均衡值为正的条件和经济系统沿二维稳定流形收敛于稳定点的条件     

地区经济发展的不平衡与经济增长

本文用两部门内生增长模型分析了在地区经济发展不平衡的情况下 ,经济发展的长期趋势 .在这个模型中 ,假定物质资本和人力资本可以不受限制的自由流动 ,技术是外生给定的 .研究发现 ,地区差别使发达地区的经济发展更快 ,落后地区的经济发展更慢 ;发达地区将有更高的均衡利率 .最后 ,文章给出了具体的政策建议 ,并对某些政策给予了评价 .     

Effect of gravity on subject-specific human lung deformation

A biomechanical model of human lung is developed and used to investigate the effect of gravity on lung deformation. The lung is assumed to behave as a poro-elastic medium with spatially dependent elastic property. Finite element analysis is performed on a three-dimensional (3D) lung geometry reconstructed from a four-dimensional Computed Tomography (4DCT) scan dataset of human patient. The spatially dependent Young’s modulus (YM) values are estimated using inverse analysis from a linear elastic deformation model. The predicted deformation of selected landmarks is monitored with and without gravity, and compared with data obtained from 4DCT registration. The results show that gravity indeed significantly affects the magnitude and distribution of lung deformation with the maximum displacement enhanced by 54% in the direction of gravity, for the conditions investigated. In summary, the accuracy of predicted deformation is improved through incorporation of gravity in the biomechanical model of lung.