血清总胆红素与冠状动脉粥样硬化相关性的探讨

目的探讨血清总胆红素(TBIL)水平与冠状动脉粥样硬化的关系.方法根据178例冠状动脉造影的结果,将其分成正常组与疾病组,疾病组中依据冠状动脉狭窄程度和范围分成轻度狭窄组和重度狭窄组,根据临床、心肌酶学、心电图又将疾病组分为急性冠状动脉病变组和非急性冠状动脉病变组,将各组的血清TBIL进行比较分析.结果正常组血清总胆红素显著高于疾病组(P<0.01),血清TBIL水平与冠状动脉粥样硬化狭窄程度和范围呈负相关(P<0.01),急性冠状动脉病变患者血清总胆红素水平明显升高(P<0.01).结论血清总胆红素对冠状动脉可能有一定的保护作用.     

Messung des Reinigungsverlaufs von Milchtanks

Zur Verfolgung des zeitlichen Verlaufs von Reinigungsvorgängen in Milchtanks wurde Milch mit unstabilisiertem kolloidalem ¹⁹⁸Au markiert. Die Messung der “Schmutzmenge” erfolgte an der Innen- oder Auβenwand bzw. im ausflieβenden Schmutzwasser. Das Verfahren wurde wiederholt zur Prüfung bei der Entwicklung von Tankreinigungsgeräten angewendet.     

Significance of plaque morphology in modifying flow characteristics in a diseased coronary artery: Numerical simulation using plaque measurements from intravascular ultrasound imaging

The paper deals with numerical investigation of the effect of plaque morphology on the flow characteristics in a diseased coronary artery using realistic plaque morphology. The morphological information of the lumen and the plaque is obtained from intravascular ultrasound imaging measurements of 42 patients performed at Cleveland Clinic Foundation, Ohio. For this data, study of Bhaganagar et al. (2010) [1] has revealed the stenosis for 42 patients can be categorized into four types – type I (peak-valley), type II (ascending), type III (descending), and type IV (diffuse). The aim of the present study is to isolate the effect of shape of the stenosis on the flow characteristics for a given degree of the stenosis. In this study, we conduct fluid dynamic simulations for the four stenosis types (type I–IV) and analyze the differences in the flow characteristics between these types. Finely refined tetrahedral mesh for the 3-D solid model of the artery with plaques has been generated. The 3-D steady flow simulations were performed using the turbulence (k–ε) model in a finite volume based computational fluid dynamics solver. The axial velocity, the radial velocity, turbulence kinetic energy and wall shear stress profiles of the plaque have been analyzed. From the axial and radial velocity profiles results the differences in the velocity patterns are significantly visible at proximal as well as distal to the throat, region of maximum stenosis. Turbulent kinetic energy and wall shear stress profiles have revealed significant differences in the vicinity of the plaque. Additional unsteady flow simulations have been performed to validate the hypothesis of the significance of plaque morphology in flow alterations in diseased coronary artery. The results revealed the importance of accounting for plaque morphology in addition to plaque height to accurately characterize the turbulent flow in a diseased coronary artery.     

A Strategy for Rapid Construction of Blood Vessel‐Like Structures with Complex Cell Alignments

A method is developed that can rapidly produce blood vessel‐like structures by bonding cell‐laden electrospinning (ES) films layer by layer using fibrin glue within 90 min. This strategy allows control of cell type, cell orientation, and material composition in separate layers. Furthermore, ES films with thicker fibers (polylactic‐co‐glycolic acid, fiber diameter: ≈3.7 µm) are used as cell‐seeding layers to facilitate the cell in‐growth; those with thinner fibers (polylactic acid, fiber diameter: ≈1.8 µm) are used as outer reinforcing layers to improve the mechanical strength and reduce the liquid leakage of the scaffold. Cells grow, proliferate, and migrate well in the multilayered structure. This design aims at a new type of blood vessel substitute with flexible control of parameters and implementation of functions.     

Q345R疲劳裂纹扩展过程的声发射研究

为了建立疲劳过程与声发射参数之间的关系,对压力容器常用钢材的典型代表——Q345R的疲劳裂纹扩展过程的声发射信号进行详细研究. 结果表明:Q345R疲劳裂纹扩展的声发射过程分为三个明显的阶段,累积计数值和累积能量值可以很好地表征整个疲劳裂纹扩展过程;声发射参数在第2阶段到第3阶段的转折点比线弹性断裂力学定义下的要提前,表明声发射技术对疲劳进入失稳扩展阶段更加敏感;建立了Q345R声发射计数率和能量率与疲劳裂纹扩展速率的关系,它可以为Q345R剩余寿命的预测提供依据.     

丝网结构对连通容器抑爆效果的影响

为了考查多层丝网结构对连通容器内气体爆炸的抑制作用,以甲烷-空气混合物为研究对象,利用0.022m3和0.113m3 2个球形容器与一段2m长的管道构成的连通容器进行了一系列丝网结构的抑爆实验,对比分析了20,40,60目和1,3,5,7,9层等不同丝网结构对连通容器的抑爆效果,并通过理论分析和数据处理得到最佳的抑爆结构。结果表明,丝网结构对传爆容器中的爆炸强度的影响要大于起爆容器;当丝网层数较少时,目数对大、小球的爆炸压力影响较小,丝网结构对连通容器不但没有抑爆作用,反而有增加爆炸强度的作用;当丝网层数较多时,目数对大、小球的爆炸压力影响较大;当丝网目数相同时,层数越多,爆炸抑制效果越好。实验条件下,5层和7层分别是40目和60目丝网结构抑爆的临界层数;与5层40目丝网结构相比,7层60目的丝网抑爆效果更好。因此,在实际设计中,应根据其综合作用选择最佳的抑爆结构。     

原子吸收光谱法检测血清铁、红细胞内铁及血清铁蛋白、 MCH、MCHC含量与老年冠心病、高血压病关系的研究

应用原子吸收光谱法检测了老年高血压、冠心病患者血清铁、红细胞内铁及血清铁蛋白、ＭＣＨ、ＭＣＨＣ。发现老年冠心病患者血清铁、红细胞内铁、血清铁蛋白含量明显高于对照组（Ｐ＜０．０１）。老年高血压患者血清铁蛋白、红细胞内铁、ＭＣＨ、ＭＣＨＣ也明显高于对照组（Ｐ＜０．０１）,血清铁与对照组比较有显著性差异（Ｐ＜０．０５）。结果表明：老年高血压,冠心病患者存在铁代谢异常,其游离铁与储存铁的增加可能是其发病的危险因素之一。     

家兔背阔肌、后斜方肌、股薄肌和小腿三头肌动脉血管构筑初探

近年来,根据临床的需要和肌瓣、肌皮瓣移植手术的开展,有关肌肉血管应用解剖学的研究逐渐引起人们的重视．在用到临床之前必须有充足的动物实验作依据,但实验动物肌肉内的血管构筑情况目前仍是个空白．本文就是针对这一实际,对三十例经铅丹油造影剂灌注的家兔,进行大体解剖,并进行软Ｘ线造影,观察动脉血管在背阔肌、后斜方肌、股薄肌和小腿三头肌的分支类型,分布范围,同时测量动脉主干直径,从而确定家兔八块表层肌肉内动脉血管（营养血管）构筑的特征     

猪血管脱细胞细胞外基质制备的初步探讨

采用高渗、低渗溶液,结合去污剂—酶联合处理猪腹主动脉,进行组织学检查,从而制备血管脱细胞细胞外基质。结果表明:经该法处理的猪血管细胞全部脱除,细胞外基质保持完好,未见胶原纤维、弹性纤维有断裂现象。作者认为,高渗、低渗溶液结合去污剂—酶联合处理,是制备血管脱细胞细胞外基质理想的方法。     

舌体高光谱的高血压患者中合并冠心病的筛查方法

高血压合并冠心病是高血压疾病的一类严重合并症.目前高血压患者对合并冠心病的情况检测不及时,容易导致严重事件的发生,其致残率、致死率极高,严重影响患者的生活质量.因此对高血压患者合并冠心病的早期发现对预防更严重事件的发生显得尤为重要.舌体信息与心血管功能关系密切,为此,提出一种基于舌体高光谱用于高血压患者中合并冠心病筛查...