色谱技术在中药指纹图谱研究中的应用

 介绍了气相色谱、高效液相色谱、超临界流体色谱和高速逆流色谱等几种色谱技术在中药指纹图谱研究中的应用现状,以及使用模糊聚类分析和人工神经网络分析指纹图谱对中药进行模式识别和质量鉴定的方法。     

中药微量元素研究中若干热点课题

评进了当前中药徽量元素研究中的若干热点课题；1．微量元素与中药品种、产地的关系；2．微量元素与中药性味、归经，功效的关系；3．中药微量元素的存在状态；4．中药内有机成分与微量元素的相互关系；5．微量元素对中西药配伍的影响；6．微量元素的毒副作用．共引用文献29篇．     

多组分光谱相关色谱及其在中药色谱指纺图谱分析中的应用

基于正交投影理论和相关色谱方法提出多组分光色谱方法提出多组分光谱相关 色谱。为克服联用色谱仪器的不等性噪声影响，采用目标组分投影前后的光谱夹角 余弦判据，判断不同的中药色谱指纹图谱的相关组分色谱峰簇。该方法为中药指纹 图谱的数据处理、合理评价以及中药谱效学的基本理论研究提供一种实用的工具。     

Fermentation characteristics and the dynamic trend of chemical components during fermentation of Massa Medicata Fermentata

As a representative of traditionally fermented Chinese medicine, Massa Medicata Fermentata (MMF) shows the functions of invigorating the spleen and stomach and promoting digestion, which plays an important role in the treatment of gastrointestinal diseases. The fermentation mechanism and the key factors that affect the quality of MMF have not been revealed yet, which has become an urgent issue that limits its clinical application. This article aims to systematically and comprehensively reveal the transformation of physical properties and the dynamic trend of chemical components including substrate components, volatile components, and lactic acid as anaerobic fermentation product during MMF fermentation. Along with obvious hyphae growth observed for MMF, the weight of MMF decreased, and the moisture and temperature increased. Through the quantified 14 components from substrate, ferulic acid increased from 45.53 ± 6.94 to 141.89 ± 78.40 μg/g, while glycosides and phenolic acids declined except caffeic acid. Also, within the 66 volatile components analyzed, alcohols and acids increased, while aldehydes and ketones decreased. Lactic acid was not detected in the fermentation substrate, but an apparent increase in lactic acid content was observed along with the increased fermentation days, resulting in 2.54 ± 0.15 mg/g on day 8. Based on the tested components, the fermentation process of MMF was discriminated into three distinct stages by principal component analysis, and an optimal fermentation time of four days was proposed. The results of this study will be of great significance to clarify the characteristics of fermentation and conduce to improving quality standards of MMF.     

基于脑涨落图和抑郁评分系统评价中医综合治疗抑郁症的疗效

以DEP患者作为研究对象,利用脑涨落图仪（EFG）的客观检查方法及DEP现代医学评分系统,评价解郁合欢汤+五行音乐疗法的中医综合治疗方式对DEP的疗效。指标包括EFG检测大脑神经递质相对功率值、汉密尔顿抑郁量表（HAMD）以及蒙哥马利抑郁评定量表（MADRS）。EFG结果显示,患者治疗后脑内γ-氨基丁酸的相对功率值较治疗前显著降低（P<0.001）,去甲肾上腺素（P<0.001）、多巴胺相对功率值（P<0.001）较治疗前显著提高,患者治疗后的HAMD(P<0.001)、MADRS(P<0.001)较治疗前显著降低。说明中医综合疗法对DEP的疗效确切,可通过对大脑神经递质的调节作用而发挥抗抑郁疗效。     

气候对安徽中药材产业经济影响分析——基于经济气候模型

通过考虑气候和经济社会因素,将气候因素与函数综合考虑并进行分析,构建“经济气候”模型,分析并得出气候因素对安徽省中药材产业影响程度,利用所构建BP神经网络模型,分析数据,对气象因素对中药材产业的影响结果进行预测。通过分析安徽省气候变化的特点与方向,确定气候因素对中药材产业的影响程度,为中药材产业发展提供一定的数据分析支撑,为有针对性的管理中药材产业提供方法与数据基础,同时对降低严重气象灾害对中药材生产带来的负面作用具有一定的理论与实践意义。     

新疆产12种中草药中微量金属元素的测定

本文测定了新疆产新疆党参,新疆元胡等１２种中草药中十种微量金属元素的含量．结果表明这些中草药中具有显著生理活性的Ｚｎ、Ｆｅ、Ｃｕ、Ｍｎ等元素．它们的含量除了个别样品外均大于或接近于国内其它地区所产的同种中草药、根据冠心病病因的Ｚｎ／Ｃｕ值假说和微量金属元素的含量关系,新疆产１２种中草药也可用于防治冠心病．     

Chronology of environmental events over East Asia during the past 130 ka

In the transitional region between the Loess Plateau and deserts, 4 sections located respectively at Yuling, Hengshan, Dingbian and Huining of China are studied. The high-resolution paleoclimatic records obtained show that environmental events on varying time scales have happened over East Asia. These events are dated with the time scales established using the recently-developed approach of Automatic Orbital Tuning. This leads to the establishment of the chronology of the environmental events.     

用VB来开发辅助教学软件

本文首先介绍了基于中文Ｗｉｎｄｏｗｓ９５平台的最新版ＶｉｓｕａＬ Ｂａｓｉｃ５．０的特点,然后以纵横码辅助教学软件开发为便,阐述了用ＶＢ开发多媒体辅助教学软件的方法、步骤,并给出了开发过程中的关键技术。     

人工杉木林木材化学成分的变异规律

应用正交试验设计方法,系统分析了不同林龄,立地条件和林分密度下杉木人工林木材化学成分含量的变异规律。结果表明：影响人工杉木林木材化学成分含量的主导因子是林龄,其次是立地条件,林分密度影响最小。综合人工杉木林不同林龄,立地条件和林分上木材化学成分含量考虑,其纸浆材主伐年龄以１７－２３年左右较好。