Biocompatibilities of sapphire and borosilicate glass as cortical neuroprostheses

The in vivo biocompatibility of pure sapphire and borosilicate glass (BSG) implanted onto the cerebral cortex was studied via magnetic resonance imaging (MRI) and histopathology. Each implant was embedded onto the cortical surface of an adult rat brain for a total of 28 days. Rats underwent surgery with and without implants, and rats with purposely damaged cortical implant sites were also studied. Each animal was imaged via MRI before surgery as well as 10 and 28 days after the surgery. Histopathological results of animals were obtained on the 28th day to determine the specific effect on neurons. Despite the fact that sapphire has been widely used in a variety of medical implants, both MRI and histopathological results indicate that pure sapphire is not biocompatible with the cerebral cortex. On the contrary, BSG implants appear to be biocompatible with the cortical surface.     

脑瘫患儿家长心理问题及对策

目的:探讨脑瘫患儿家长的心理状态,为临床工作提供参考。方法:采用症状自评量表(SCL-90),调查患儿家长存在的心理问题。结果:根据患儿家长存在的不同心理问题采取相应的措施,减轻患儿父母心理负担,提高治疗依从性。结论:脑瘫患儿家长存在心理障碍,在临床工作中要注意加强对患儿家长进行心理护理。     

Measuring steady-state cerebral vasomotor reactivity using non-triggered phase-contrast magnetic resonance imaging

To investigate cVMR by using CO2-based hypercapnic challenge and blood flow monitoring employing non-triggered phase contrast (PC) magnetic resonance imaging. Six healthy volunteers (6 male; mean age: 29 years) participated this study after providing institutionally approved consent. This study used non-triggered PC imaging to increase temporal resolution of dynamic blood flow measurements, allowing real-time monitoring of the hypercapnic challenge response. Results suggest that vasomotor reactivity measured by non-triggered PC imaging is positively associated with the concentration of inhaled CO2. This study concludes that CO2 challenge combined with non-triggered PC flow imaging is potentially useful to provide diagnostic information for patients with cerebrovascular disease.     

缺血性脑卒中蒙西医治疗现状

缺血性脑卒中是最常见的脑血管病,严重威胁着人类健康。不同的医学体系对其治疗亦不同,现就蒙医与西医对缺血性脑卒中治疗的现状作一综述。     

应用阿司匹林和低分子肝素钙治疗100例急性脑梗塞疗效分析

目的 临床观察阿司匹林和低分子肝素钙联合治疗急性脑梗塞的疗效.方法 通过对100例在48 h内急性脑梗塞病例随机分为治疗组(给予肠溶阿司匹林和低分子肝素钙治疗)和对照组(只给肠溶阿司匹林,不给予低分子肝素钙治疗)进行疗效对比观察4周.结果 治疗组与对照组比较,总有效率(P＜0.05)有显著提高,副作用小,两组无差异.结论 使用肠溶阿司匹林和低分子肝素钙联合治疗急性脑梗塞疗效好,使用简便、安全、经济,可在临床予推广应用.     

蓝布正对小鼠脑缺血的保护作用

目的:观察蓝布正对小鼠脑缺血的保护作用。方法:不完全结扎小鼠一侧颈总动脉及迷走神经,另侧完全结扎造成脑缺血,观察12h存活时间和死亡率;结果:与生理盐水对照组比较,蓝布正12,24和48gk/gig可以延长存活时间,分别延长了45%(P>0.01),199%(P<0.05)和206%(P<0.01);降低死亡率,分另降低了6.8%(P>0.01),46%(P<0.05)和57%(P<0.01),均呈一定的剂量相关趋势。蓝布正12,24和40gk/gig能提高小鼠对耐缺氧实验的耐受作用。结论:蓝布不对小鼠脑缺血具有保护作用。