Nerve growth factor activity of several immunal related serine proteases

Rabbit was immuned by the previously purified protein with high nerve growth factor (NGF) bioactivity (NGF_like protease) from \%Agkistrodon halys Pallas\% and the antisera were collected. The polyclonal antibodies were tentatively purified and then used as ligands of an affinity column. The \%A.h.Pallas\% crude venom was fractionated by this affinity column and then by Mono Q on fast protein liquid chromatography (FPLC). As a result, fraction Ⅱ and fraction Ⅲ were purified respectively, whose N_terminal amino acid sequences show high homology with the serine proteases in snake venoms, as well as the previous NGF_like protease. However, they possessed different levels of NGF bioactivity. The NGF activity of the previous NGF_like protease is equivalent to that of NGF, while the activity of fraction Ⅱ seems relatively low in contrast to fraction Ⅲ which had no NGF activity.     

鹦鹉舌下神经气管鸣管支运动核团的定位

用辣根过氧化物酶（ＨＲＰ）逆行示踪技术，对澳洲鹦鹉舌下神经气管鸣管支（ＮＸⅡｔｓ）延髓运动团进行定位研究，结果显示在ＮＸⅡｔｓ和上颈肌注射ＣＴＢ－ＨＲＰ后，逆标细胞出现在舌下神经核气管鸣管亚核（ｎＸⅡｔｓ）、舌咽－迷走背运动核（ｎⅨ－Ｘ）、上脊髓核（ＳＳＰ）和颈静脉神经节（ｊｕｇ·ｇｇｌ）。ｎＸⅡｔｓ对ＮＸⅡｔｓ的支配是双侧性的（同侧为主）。这些结果表明，ＮＸⅡｔｓ兼有发声运动和感觉传入双重功能。     

上海城市发展对土地需求规律的量化研究

在分析上海产业政策和区域经济发展对用地需求的基础上，通过对土地需求、土地储备与土地供应的关联分析，建立了基于BP神经网络的预测模型，研究了上海经营性用地需求趋势的分析和对具体指标的细化分析．进一步地得出土地需求总量，提出了至2010年上海经济发展对土地需求的预测分析，以合理确定土地储备量．     

直流伺服系统滑模变结构-神经网络控制的研究

针对直流伺服系统特点，根据现代控制理论，提出了滑模控制—神经网络策略，理论研究和实验表明，系统有较好鲁棒性和动静态特性。     

抄纸过程的BP神经网络PID控制

为了使抄纸过程的输出(湿度和基重)最大限度地接近给定值,采用BP神经网络PID控制。此控制器由PID控制器和BP神经网络组成,采用BP算法进行PID参数的在线调整,使输出值较好地跟踪了给定值,能达到较好的控制效果,并为抄纸过程的控制提供另一种思路。     

针刀结合手法治疗神经根型颈椎病

介绍神经根型颈椎病的诊断、针刀治疗和手法治疗的方法 ,详细分析了针刀和手法治疗对神经根型颈椎病的治疗效果 ,认为小针刀加手法治疗神经根型颈椎病 ,见效快 ,治疗时间短 ,不易复发 ,又实惠经济     

汽车ESA点火提前角数据生成方法的研究

针对汽车ESA比现行控制策略的局限性，提出了6种汽车发动机ESA控制策略的数学模型及点火提前数据生成方法，以利于提高点火控制精度，从而使发动机的工作状态达到最佳．     

Dog sciatic nerve gap repaired by artificial tissue nerve graft

The feasibility of repairing dog sciatic nerve damage by using a biodegradable artificial tissue nerve graft enriched with neuroregenerating factors is investigated. The artificial nerve graft was implanted to a 30 mm gap of the sciatic nerve damage in 7 dogs. The dogs with the same nerve damage that were repaired by interposition of the autologous nerve or were given no treatment served as control group 1 or 2, respectively. The observations include gross and morphological observations, immune reaction, electrophysiological examination, fluorescence tracing of the neuron formation and the number of the neurons at the experimental sites, etc. Results showed that 6 months after the implantation of the graft, the regenerated nerve repaired the damage of the sciatic nerve without occurrence of rejection and obvious inflammatory reaction in all 7 dogs, and the function of the sciatic nerve recovered with the nerve conduction velocity of (23.91±11.35)m/s. The regenerated neurons and the forming of axon could be observed under an electron microscope. This proves that artificial tissue nerve graft transplantation can bridge the damaged nerve ends and promote the nerve regeneration.     

中老年2型糖尿病患者糖尿病痛苦影响因素及对策的研究

目的 探讨中老年2型糖尿病患者糖尿病痛苦影响因素并总结相关对策实施效果。方法 抽取2020年1月~2020年6月井冈山大学附属医院收治的140名中老年2型糖尿病患者,使用中文版糖尿病痛苦量表（CDDS）评估本组患者糖尿病痛苦情况。同时本组患者接受正念训练,持续6个月后评估本组患者糖尿病痛苦量表与生活质量量表结果变化。结果 140例患者CDDS量表总分为（41.45±14.42）分,平均（2.55±0.86）分。患者性别、文化背景、家庭收入、病程长短、并发症等均存在统计学意义（P<0.05）。患者文化背景、病程长短是导致中老年2型糖尿病患者糖尿病痛苦的主要影响因素。持续6个月正念训练干预后本组患者CDDS量表得分相较干预前得分均有明显降低（P<0.05）。结论 文化背景与病程长短是导致中老年2型糖尿病患者糖尿病痛苦的主要影响因素,正念训练干预措施能有效缓解中老年2型糖尿病患者痛苦程度,具有积极价值。     

青光眼发病机理——筛板变形研究进展

青光眼是世界上第一大不可逆致盲眼病.其病变与眼内压直接相关,控制眼内压是目前控制青光眼发展的唯一有效途径,但发病的确切机制尚未明确.现已证实,青光眼的原发部位是巩膜筛板:由筛板前后分别承受的眼内压与颅内压产生的压力差会导致筛板结构与形态发生变化,进而挤压穿过筛板的视觉神经,造成视觉神经损伤,产生不可逆的视觉损失.因此,青光眼的发病机理与筛板的力学特性及其周围的力学环境密切相关.自从筛板被确定为青光眼视神经损害的原发部位,筛板便成为该领域的研究热点.其中,通过建立筛板力学模型,研究眼内压与颅内压作用下筛板的受力变形,进而分析筛板变形对视神经的损伤,有助于揭示青光眼视神经损伤机制及青光眼的发病机理.本文将从相关实验、理论和计算以及临床等方面介绍青光眼发病机理中筛板变形的研究进展以及目前存在的问题.