全文获取类型
收费全文 | 11462篇 |
免费 | 247篇 |
国内免费 | 127篇 |
专业分类
化学 | 465篇 |
晶体学 | 12篇 |
力学 | 80篇 |
综合类 | 15篇 |
数学 | 9573篇 |
物理学 | 654篇 |
综合类 | 1037篇 |
出版年
2023年 | 21篇 |
2022年 | 43篇 |
2021年 | 39篇 |
2020年 | 71篇 |
2019年 | 296篇 |
2018年 | 289篇 |
2017年 | 182篇 |
2016年 | 159篇 |
2015年 | 151篇 |
2014年 | 328篇 |
2013年 | 669篇 |
2012年 | 337篇 |
2011年 | 676篇 |
2010年 | 577篇 |
2009年 | 756篇 |
2008年 | 877篇 |
2007年 | 901篇 |
2006年 | 676篇 |
2005年 | 444篇 |
2004年 | 420篇 |
2003年 | 391篇 |
2002年 | 319篇 |
2001年 | 249篇 |
2000年 | 246篇 |
1999年 | 282篇 |
1998年 | 241篇 |
1997年 | 173篇 |
1996年 | 246篇 |
1995年 | 223篇 |
1994年 | 209篇 |
1993年 | 174篇 |
1992年 | 126篇 |
1991年 | 95篇 |
1990年 | 95篇 |
1989年 | 94篇 |
1988年 | 62篇 |
1987年 | 62篇 |
1986年 | 66篇 |
1985年 | 91篇 |
1984年 | 62篇 |
1983年 | 51篇 |
1982年 | 63篇 |
1981年 | 61篇 |
1980年 | 56篇 |
1979年 | 40篇 |
1978年 | 44篇 |
1977年 | 35篇 |
1976年 | 38篇 |
1975年 | 10篇 |
1974年 | 8篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
191.
V. G. Berezkin A. A. Korolev I. V. Malyukova R. G. Mardanov 《Russian Chemical Bulletin》1997,46(12):2064-2073
The effects of the carrier gas nature and pressure on the relative retention values of organic compounds were studied using
a series of capillary columns differing in the film thickness of the polar stationary phase (PEG-20M). Relative retention
depends linearly on the carrier gas pressure. This dependence becomes more pronounced in the following order of carrier gases:
helium < nitrogen < carbon dioxide. The limiting relative retention at a carrier gas pressure approaching zero rather than
relative retention values measured experimentally (relative retention time, Kovats retention index,etc.) is an invariant characteristic of a compound subjected to chromatography. For the carrier gases studied, the limiting retention
values almost does not depend on the nature of the carrier gas used. The limiting indicating the complex absorption-adsorption
nature of these parameters. Dissolution of a carrier gas in the stationary liquid phase has an effect on the relative retention.
Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2177–2186, December, 1997. 相似文献
192.
Jian Lin Li Peiyu Ding Baocheng Jiang Min Yang Jie Ren Yan Song 《Natural product research》2019,33(10):1393-1398
Microbial transformation of 20(R)-panaxatriol by the fungus Aspergillus flavus Link AS 3.3950 was performed. Four new (1–4), along with two previously reported metabolites (5 and 6), were obtained. Their chemical structures were elucidated on the basis of extensive spectroscopic analyses. Furthermore, the inhibitory effects of those compounds on K562/ADR, Du-145, Hela, MCF-7 and HepG2 cell lines were evaluated by MTT assay. Among them, compound 15β-hydroxy-20(R)-panaxatriol (4) exhibited selective inhibitory effects on human leukaemic progenitor cells K562/ADR through arresting cell cycle, which was associated with obvious decrease of cyclin B1, cyclin D1 and cyclin-dependent kinase (CDK) 1/2/4/6 protein expression. 相似文献
193.
194.
Both STO-3G ab initio and s-p separation-type-modified INDO semiempirical methods were applied to molecular-orbital calculation of the N20 molecule. From these two methods, the optimized bond distances between the nearest N atoms (dn-n) and the most calculated thermodynamic data are close to each other. The positive values of ΔHa° and ΔGa° for the atomization reaction in this work prove that N20 is stable. In contrast to conventional INDO and MINDO/3, but similar to former AMI and MNDO calculations, both ΔHr° and ΔGr° are positive in the formation reaction, which indicates that N20 belongs to the category of high-energy molecules. 相似文献
195.
N. G. Komissarova N. G. Belenkova L. V. Spirikhin O. V. Shitikova M. S. Yunusov 《Chemistry of Natural Compounds》2002,38(1):58-61
Oxidation of betulin by pyridinium dichromate, pyridinium chlorochromate, and K2Cr2O7 -H2SO4 in the presence of tetrabutylammonium bromide was studied. Products of regioselective C-3, C-28-, and exhaustive oxidation, 28-hydroxylup-20(29)-3-one, 3-hydroxy- and 3-oxolup-20(29)-en-28-al were obtained. 相似文献
196.
197.
Semiempirical calculations, at the PM3 level provided within the Winmopac v2.0 software package, are used to geometrically optimize and determine the absolute energies (heats of formation) of a variety of C(20) isomers that are predicted to exist in and around the ring and cage isomers. Using the optimized Cartesian coordinates for the ring and the cage isomers, a saddle-point calculation was performed. The resulting energy profile, consisting of a series of peaks and valleys, is used as a starting point for the identification and location of fifteen additional isomers of C(20) that are predicted to be energetically stable, both via geometry optimizations and force constant analysis. These additional isomers were subsequently determined to lie adjacent to one another on the potential surface and establish a step-wise transformation between the ring and the cage. Transition-state optimization of the Cartesian coordinates at the saddle point between adjacent isomers was performed to quantify the energy of the transition state. The step-wise process from one isomer to another, which extends out over the three-dimensional surface, is predicted to require approximately 15% less energy than that of the direct, two-dimensional transformation predicted in the bowl-cage profile. However, the net atomic rearrangement for the step-wise process is about four times greater than that of the direct process. Although less in energy, the amount of atomic rearrangement in the step-wise process would make the occurrence of such a route prohibitive. Utilizing the direct distance separating the three primary isomers (ring, bowl, cage), the method of triangulation is performed to quantitatively position other C(20) structures on the potential surface, relative to the ring, bowl, and cage isomers. 相似文献
198.
The chelate oxides of bis(trimethylantimony) (Me3SbL1)2O (i = 1 or 2, L1-acetylacetonate, L2 - trifluoroacetylacetonate) and bis(triethylantimony) (Et3SbL1)2O have been obtained in 79–85% yields by a one-step oxidation of trialkylantimony withtertbutylhydroperoxide in the presence of -diketones in benzene at 20 °C.Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 1, pp. 154–155, January, 1995.This work was carried out with financial support from the Russian Foundation for Basic Research (Project No. 94-03-08846). 相似文献
199.
200.
Aibrohim Dramae Sutichai Nithithanasilp Wilunda Choowong Pranee Rachtawee Samran Prabpai Palangpon Kongsaeree Pattama Pittayakhajonwut 《Tetrahedron》2013
Two new natural products, samroiyotmycins A (1) and B (2), along with two naturally new novclobiocin 101 (3) and 4-hydroxy-3-(3-methylbut-2-enyl)benzamide (5), and five known substances including neoantimycin, clorobiocin (4), 29-O-methylabierixin, daidzein, and 1-(3-indolyl)-2,3-dihydroxypropan-1-one have been isolated from Streptomyces sp. BCC33756. Their chemical structures were determined based on NMR spectral information and the relative stereochemistry of compound 1 was determined by X-ray crystallographic data. Both samroiyotmycins A and B exhibited antimalarial activity against Plasmodium falciparum K1—multi-drug resistant strain, with IC50 values of 3.65 and 3.16 μg/mL, respectively. Compound 1 was inactive against both cancerous (MCF-7, KB) and non-cancerous (Vero) cells, while compound 2 displayed cytotoxicity against Vero cell with IC50 value of 29.57 μg/mL. 相似文献