118例影响美容的五种皮肤病头发微量元素测定分析

对118例影响美容的痤疮、黄褐斑等5个病种进行了成人头发的Zn、Fe、Cu，Ca铡定和统计学处理，结果表明，各病的发锌和发钙普遗低于正常值，提示它们与微量元素关系。     

100例皮肤病患者发样微量元素的检测及多因素分析

对100例皮肤病患者发样中的Zn、Cu、Fe、Ca及Mg五种元素进行了检测，采用主成分分析及因子分析法对分析数据进行了统计学处理，探索皮肤病与该五种元素的关系，结果表明：Zn、Mg元素水平是皮肤病的重要样本特征，其中Mg元素是皮肤病的一个重要影响因子。其水平偏高及偏低者占病例数的92％；Cu、Fe元素水平基本正常；缺Zn影响则不是主要因素，低Zn者只占8％。可将皮肤病分为两大类：(1)Zn、Mg元素水平偏高类；占病例数的58％。(2)Ca、Mg元素水平偏低类，占病例数的32％。     

QQ在线

1 问：编辑同志，我是一位陕西的忠实读者，我上初三时得了一种皮肤病，看了许多医生都没见好。想通过贵刊了解一下这是什么病？     

Identification of Caspasecleavage site in the apoptosis suppressor protein P49 from the<Emphasis Type="Italic">Spodoptera littoralis</Emphasis> nucleopolyhedrovirus

The p49 gene from baculovirus Spodoptera littoralis nucleopolyhedrovirus (SINPV) was able to suppress apoptosis of 5~9 cells induced by virus infection. Ectopically expressed P49 protein had the capacity to inhibit the activity of Caspases, being the executioner of apoptosis. Digestion of P49 with human Caspase or Bm-Caspase both yielded 10 and 40 kD fragments. Checking the sequence of P49, we found that the motif 91-TVTDG-95 of P49 was the sequence recognized by Caspases. The mutant of P49, Asp94Ala, could not be cut by both caspases and lost its caspases inhibition.Meanwhile, Thr91Ala mutant permitted the cleavage and partially retained its activity of caspases inhibition. We also found that P49 was a substrate of upstream initiator caspase and downstream effector Caspases, indicating that P49 was a broad specificity Caspase inhibitor.     

全反式维甲酸的合成新方法

全反式维甲酸(all trans-Retinoic acid,Vitamin A acid,1),对各类型痤疮与皮肤癣症疗效显著,用以治疗粉刺和防治皮肤皲裂效果甚佳。近几年来,发现它能抗皮肤癌,尤其令人鼓舞的是,它能促进入肝癌细胞的表型向正常方向逆转。可见1的生物活性及医药