Effects of swimming associated with risedronate in osteopenic bones: An experimental study with ovariectomized rats

Physical activity and risedronate sodium have effects on metabolic bone diseases, maintaining the integrity of bone tissue. Our objective was to evaluate the effects of swimming associated with risedronate as a prophylactic means in osteopenic bone of ovariectomized rats. A total of 24 animals of the Wistar strain were used and separated into four groups containing six animals: Ovariectomy (OVX), ovariectomy and swimming (OVXS), ovariectomy and risedronate (OVXM), ovariectomy, risedronate and swimming (OVXMS). The effectiveness of the treatments were evaluated using the tibia by means of biomechanical, radiographic, histomorphometric analyzes. Statistical analysis was performed by the non-parametric Kruskal–Wallis test (p < 0.05). The OVXM and OVXMS groups showed higher values ​​compared to OVX in maximum strength and rigidity. Microscopic analysis showed increased trabecular bone in the OVXM group in relation to the others, and in the OVXMS compared to OVXS. Proximal densitometry in the OVXM and OVXMS groups showed higher values than the OVX and OVXS groups. There were no significant differences in overall densitometry. In conclusion, when comparing the prophylactic means, risedronate was able to preserve bone mass significantly, unlike exercise where an improvement of bone tissue was observed, although not significant, and when swimming and risedronate are combined the result was even better.     

测绘工程专业CAD课程教学改革与实践

结合测绘工程专业本身的特点，该文首先介绍了CAD课程的作用，分析了该课程的教学现状，总结了在现实教学中存在的问题，进一步引出教学改革的必要性。接下来结合实际教学经验，分别从课程的教学内容、教材的选择、教学方法与教学手段、考核方式、师资队伍建设等方面探讨了AutoCAD教学的改革措施，对提高CAD课程教学质量，培养学生实际动手能力，更好地将CAD应用到专业中，适应实际行业工作需求，具有十分重要的意义。     

论体育学院网球专选课教学改革

对体育学院网球专选的学生技术进行了分类，同时又对网球专选课教学现状进行了分析，提出了教学改革的措施．     

关于高师院校计算机专业教学改革的几点建议

本文以高等师范院校计算机专业教学改革为例,从教育观念的更新、教学模式的转变、教学手段的更新、教学对象的再认识、教学中的教材教法等多个方面分析以网络为主的现代教育模式改革的思想,目的在于探索出一条以多媒体和网络为主体的教学环境下的教育新思路。     

数据库原理及应用课程教学模式的研究与实践

本文针对目前数据库原理及应用课程在教学过程中存在的一些问题,探讨了如何从教学内容、教学目标、教学手段、教学方法以及考核方式上改进教学模式,从而提高学生的综合素质。     

与企业全方位深度融合建设精品专业

行业发展是专业建设的前提,与企业结合是专业建设的关键,与生产结合是专业建设的核心,与就业结合是专业建设的根本。航空制造业的快速发展需要大量的数控技术专业人才。数控技术专业的发展离不开与企业的良好合作。企业为专业建设注入活力,专业建设为企业发展提供保障。     

研究生英语分级教学的现状与建议

以某本科高校为例，探讨其研究生英语教学问题。对于研究生群体来说，其来源、成份复杂多元，其英语基础“贫富差距”较大。因此，对非英语专业的研究生英语进行分级教学是学校明智的举措。一年教学实践后，通过对研究生同学的问卷调查和访谈，结果表明在分级程序、课程设置、教师素质、教学理念和测试方式等方面还存在问题。     

素质教育与古代文学课程改革

素质教育是现代教育界讨论很多的话题，本文主要谈素质教育的必要性与重要性及其内涵，特别是就古代文学课程改革方面提出实施素质教育，对古代文学课程改革实行初步探索，比如辩论课、自我讲授课、作业答辩课等这些新型的课堂设计，对于学生综合素质的提高有很大的帮助。     

Single chain force spectroscopy - Reading the sequence of HP protein models

We study the elastic properties of single A/B random copolymer chains, with a specific sequence and use them as theoretical model for so called HP proteins. HP proteins carry hydrophilic (P) and hydrophobic (H) monomers. We predict a rich structure in the force-extension relations which can be attributed to the information in the sequence. The variational method is used to probe local minima on the path of stretching and releasing for the chain molecules. At a given force, we find multiple configurations which are separated by energy barriers. A collapsed globular configuration consists of several domains which unravel cooperatively. Upon stretching, the unfolding path shows a stepwise pattern corresponding to the unfolding of each domain. While releasing, several cores can be created simultaneously in the middle of the chain, resulting in a different path of collapse. The long-range interactions and stiffness of the chain simplify the potential landscape given by the disorder in sequence. Received 5 March 2002 / Received in final form 16 May 2002 Published online 13 August 2002