Extra-column effects in multi-dimensional switching systems (MDSS) — GC

In order to permit valveless MDSS operation and easy column change, the hardware designed contains several connections. These can give rise to extra-column band broadening effects. In order to quantitate such effects, the packed-capillary column configuration (without trap) was used. The band broadening caused by the connections was found to be small: 120 ms². A more practical approach was used to check the performance of the trap (re-injection) in the capillary-trap-capillary column configuration. Here the results obtained with re-injection from the trap were compared with results obtained in transfer and heart-cutting modes while the trap was heated. Re-injection was tested with n-alkanes ranging from n-C₆ to n-C₂₈. A starting peak width of 1.6 s was found.     

基于PDMS的压电驱动式系列微型泵

为进一步拓展压电微泵的应用领域,以利于更好地将其集成于微流控芯片中,该文对以固态聚二甲基硅氧烷(PDMS)为泵体材料的压电微泵开展相关实验研究。通过合理设计压电振子的支承方式、阀片结构以及采用两腔串、并联结构等措施以提高压电微泵的工作性能。分别以PDMS和聚甲基丙烯酸甲酯(PMMA)为泵体材料设计制作了单腔微泵、双腔串、并联微泵,并对其工作性能进行对比性实验测试。实验证明,构造具有较好工作性能的PDMS压电微泵具有可行性,在电压90 V,频率80 Hz的情况下,PDMS双腔串联泵的输出流量达到21mL/min,输出压力达到10kPa。但与PMMA为泵体材料的压电微泵相比,PDMS压电微泵在流量、压力方面仍有近30%的差距。     

无阀微泵泵腔中流体流动的有限元模拟与分析

采用有限元仿真软件ANSYS/FLOTRAN对收缩/扩张型无阀微泵泵腔中流体流动的全过程进行了数值模拟和仿真分析,得到了流体在整个泵腔中的流场构形和流动特性。结果表明,泵腔结构单元的弯道效应与出/入口处流体速度分布的非线性混合将导致腔中的局域涡流现象。通过对3个简单模型的模拟计算,证明了缓冲腔的不同结构对无阀微泵的整流效率有较大影响,是泵腔结构参数优化设计不可忽视的重要环节。     

LIQUID-SOLID COUPLED SYSTEM OF MICROPUMP

This paper employs the integral-averaged method of thickness to approximate the periodical flows in a piezoelectric micropump, with a shallow water equation including nonlinearity and viscous damp presented to characterize the flows in micropump. The finite element method is used to obtain a matrix equation of fluid pressure. The fluid pressure equation is combined with the vibration equation of a silicon diaphragm to construct a liquid-solid coupled equation for reflecting the interaction between solid diaphragm and fluid motion in a micropump. Numerical results of a mode analysis of the coupled system indicate that the natural frequencies of the coupled system are much lower than those of the non-coupled system. The influence of additional mass and viscous damp of fluid on the natural frequencies of the coupled system is more significant as the pump thickness is small. It is found that the vibration shape functions of silicon diaphragm of the coupled system are almost the same as those of the non-coupled system. This paper also gives the first-order amplitude-frequency relationship of the silicon diaphragm, which is necessary for the flow-rate-frequency analysis of a micropump.     

A PDMS-based thermo-pneumatic micropump with Parylene inner walls

This study demonstrated a new thermo-pneumatic micropump implemented by stacking three layers of PDMS on a glass slide. The pumping with valve-less diffuser/nozzle channel is driven due to the flow rectification effect. The large actuation stroke of the deforming diaphragm appears as the phase change from the working liquid into vapor inside the evaporation chamber by the Joule heating of the embedded heaters. With the wall temperature of PDMS below 50 °C verified by an infrared imager, the pumping flow rates are 3.5-12.5 nL/min subject to a square wave of 4 V peak-to-peak heating voltage with frequency varied from 0.3 to 3.0 Hz. After coating the micropump inner wall with a 3 μm Parylene against the gas leakage through PDMS, the micropump paid the price of decreasing the flow rate down to 2.5-6.5 nL/min.     

一种无阀压电微泵的研究

介绍了一种适用于微流体系统的无阀微泵。该微泵利用聚二甲基硅氧烷(PDMS)作为泵膜,利用硅各向异性腐蚀形成扩散口/喷口结构,并利用压电双晶片作为驱动部件。该微泵的制作工艺简单,使用寿命长,具有良好的液体驱动性能。对于使用15 mm长的压电双晶片作为驱动器的压电无阀微泵,在100 V6、0 Hz、占空比为1的方波驱动下,最大流速可达151μL/min。     

压电锥形流管无阀泵的研究—单向流动原理及泵流量

利用流体在收缩与扩张流管中流动能耗不同的原理。借助流阻系数，具体分析了压电锥形流管无阀泵在无阀状态下，产生单向流动的原因，并解析了泵流量。同时，把上述结果与实验进行了比较，证明了理论分析的正确性。     

A novel peristaltic micropump with low compression ratios

It is common for peristaltic micropumps to have large compression ratios. In the limit, the chamber of the pump is completely blocked by the membrane to prevent back flow. Different from this kind of pump, a micropump with small compression ratios is proposed in this study. With small oscillation amplitudes the membrane of the pump can reciprocate at high frequencies to improve its pumping flow. Both the multidimensional method and the lumped‐element method are employed for analysis. For this kind of peristaltic micropump the working fluid is allowed to flow freely in the forward and backward directions. Therefore, the operating sequences for the high‐compression ratio type of pumps are not appropriate. It is shown that the theoretical net flow rate is zero for the four‐phase and six‐phase modes of sequence and becomes negative for the three‐phase mode unless regulators, such as the nozzle/diffusers, are incorporated to rectify the flow. However, this pump becomes very attractive by reversing the operating sequence of the three‐phase mode because positive net flow is yielded. It is seen that with the reversed three‐phase mode and the nozzle/diffuser as connecting channels, the pumping effectiveness is greatly enhanced. The pumps with both two chambers and three chambers are under consideration in the study. Copyright ©2011 John Wiley & Sons, Ltd.     

A Multicommutated Flow System Based on an Opened‐Loop with Micropump Propulsion

Abstract

A multicommutated flow system using an opened‐loop configuration and incorporating micropump propulsion was developed and applied in the determination of highly concentrated species in wastewater samples.

The developed flow system enabled a suitable dilution level to be attained and continuously monitoring of the analytical process. A synergetic effect was also obtained with the continuous removal of the dispersed front and trailing zones of the sample plug.

The developed strategy was evaluated on the determination of iron in high concentrated wastewater samples without any pre‐treatment. The continuous sample recirculation permitted an increase in linear range up to 10 g · l^?1.     

生物芯片压电微流体泵液-固耦合系统模态分析

对压电微流体泵粘性流体周期流动进行厚度积分平均近似,得到包含粘性的,非线性浅水波动方程,并采用有限元法得到微泵液体压强矩阵方程.液体压强矩阵方程和压电硅片振动有限元方程耦合,得到一个包含微泵进出口扩散管的液-固耦合系统振动方程.液-固耦合系统的模态分析结果表明,微泵液-固耦合系统的自然频率比不耦合的硅片振动自然频率低很多.随着微泵厚度的减少,液体附加质量和粘性阻尼对耦合系统自然频率的影响更加明显.同时发现,对应的压电片振型函数在液-固耦合前后没有明显变化.还给出硅片一阶模态的振幅-频率特征曲线.对薄型无阀压电微流体泵,浅水波模型合理地表达了微泵液体流动和压电硅片振动的相互作用,以及液体附加质量和粘性阻尼对微泵液-固耦合系统动力特征的影响.