A study for quality evaluation of Taxilli Herba from different hosts based on fingerprint-activity relationship modeling and multivariate statistical analysis

In this study, a fingerprint-activity relationship modeling between chemical fingerprints and antirheumatic activity was established, and multivariate statistical analysis was used to evaluate the quality of Taxilli Herba (TH) from different hosts. Characteristic fingerprints of 20 batches of TH samples were generated by high-performance liquid chromatography coupled with triple quadrupole-time of flight tandem mass spectrometry (HPLC-Triple TOF-MS/MS), and the similarity analysis was calculated based on thirteen common characteristic peaks by hierarchical clustering analysis (HCA). Subsequently, nine efficacy markers were discovered by combining fingerprints and antirheumatic activity through grey correlation analysis (GCA) and bivariate correlation analysis (BCA). Meanwhile, the content of 5 constituents in 9 markers was determined by high-performance liquid chromatography coupled with triple quadrupole-linear ion trap tandem mass spectrometry (HPLC-QTRAP-MS/MS). The comprehensive quality of TH was assessed using multivariate statistical analysis, including principal components analysis (PCA) and technique for order preference by similarity to ideal solution (TOPSIS). The results showed that a high dose of TH extract could markedly ameliorate arthritis damage compared to other doses, with flavonoids playing an important role in the antirheumatic activity. The comprehensive quality of samples from Morus alba L. (SS) was superior to those from Liquidambar formosana Hance (FXS). The present study will demonstrate the markers associated with efficacy, and provide an applicable strategy for more comprehensive quality control and evaluation of TH.     

Mercury Speciation in Fish by High-Performance Liquid Chromatography (HPLC) and Post-Column Ultraviolet (UV)-Photochemical Vapor Generation (PVG): Comparison of Conventional Line-Source and High-Resolution Continuum Source (HR-CS) Atomic Absorption Spectrometry (AAS)

An ultraviolet-photochemical generator (UV-PVG) capable of post-column on-line transformation of both organic and inorganic mercury species to cold vapor (Hg⁰) with subsequent detection by quartz tube-atomic absorption spectrometry (QT-AAS) was developed. Mercury(II), methylmercury(I), ethylmercury(I), and phenylmercury(I) were successfully detected after separation by reversed-phase high-performance liquid chromatography (RP-HPLC). Two types of AAS detectors were compared. The first was a commonly used line-source instrument while the second was a high-resolution continuum source (HR-CS) AAS. The latter provided better limits of detection: 0.47?µg?L^?1 for Hg(II), 0.84?µg?L^?1 for methylmercury(I), 0.80?µg?L^?1 for ethylmercury(I), and 2.0?µg?L^?1 for phenylmercury(I). The repeatability at 30?μg?L^?1 was 3.6%, 4.1%, 6.2%, and 4.5% for these species (n?=?10). These figures of merit were comparable with those reported for more sensitive atomic fluorescence spectrometry. Nine sample extraction procedures were investigated. Extraction by tetramethylammonium hydroxide and HCl at 75?°C was selected as the only method compatible with the proposed separation and detection steps providing high extraction efficiency and no changes in mercury speciation. The applicability of the proposed high-performance liquid chromatography–ultraviolet-photochemical vapor generation–quartz tube-atomic absorption spectrometry method was demonstrated using fish samples and certified reference materials (CRM) DOLT-4 (dogfish liver) and ERM-CE464 (tuna fish). The results were comparable to those obtained by a reference method based on L-cysteine extraction and high-performance liquid chromatography–inductively coupled plasma-mass spectrometry (HPLC–ICP-MS) determination.     

Ising-like field theory

A field theory model onR ² in which the basic fields are Ising spins instead of Gaussian spins is examined. Using statistical mechanics techniques we discuss the ultraviolet and the infrared problems. In particular we discuss a technique yielding the asymptotic expansion in of the ground state energy, as 0, without using the cluster expansion.Supported in part by Consiglio Nazionale delle Ricerche.     

多孔导电膜刻蚀方法的改进及其在毛细管电泳蛋白进样浓缩中的应用

通过控制电压偏置方向,利用电渗流效应使毛细管多孔导电膜的刻蚀成功率得到显著提高。在刻蚀过程中于管中灌注偏碱性溶液,并在毛细管进口端与刻蚀池间施加正电压偏置。当刻蚀达到电通透时,在电渗流的作用下刻蚀自动停止,从而避免了过刻蚀。在含有2%～4%的葡聚糖的0.05mol/LTris-H3PO4(pH2.5)缓冲体系中,利用该多孔膜对溶菌酶和牛血清白蛋白实现了接近理论值的浓缩倍率。对酸碱性不同的蛋白浓缩效率的差别进行了讨论。利用电进样浓缩30min使常规光度检测器(214nm)对两个蛋白样品的检出限减小为1×10-11mol/L。     

紫外激光技术在船舶压载水处理系统中的应用

为了航行安全远洋船舶需要注入和排放压载水。压载水中的有害水生物和病原体同时也被搬运,并导致海洋水域环境的污染。控制该污染的核心措施之一是在船上增添压载水处理设备。紫外线激光二极管可以制造产生紫外线的辐射,能穿透细菌、病毒的细胞膜,破坏核酸结构,使之失去繁殖和自我复制能力,达到快速杀菌的效果。紫外激光压载水处理设备杀菌快速,无二次污染,使用安全,占地小,可操作性强,尤其适用于中小型船舶压载水处理系统。     

使用溅射AlN成核层实现大规模生产深紫外LED

高质量AlN薄膜对制造高性能深紫外器件非常重要,但是目前还很难使用大型工业MOCVD生长出高质量的AlN薄膜.采用磁控溅射制备了不同厚度的用作成核层的AlN薄膜,使用大型工业MOCVD直接在成核层上高温生长AlN外延层,研究了不同成核层对AlN外延层质量的影响.通过扫描电子显微镜和原子力显微镜对成核层AlN薄膜的表面形貌进行表征;使用高分辨X射线衍射仪对AlN外延层晶体质量进行表征,结果表明:在溅射成核层上生长的AlN外延层的晶体质量有显著提高.使用大型工业MOCVD在蓝宝石衬底上成功制备出中心波长为282 nm的可商用深紫外LED,在注入电流为20 mA时,单颗深紫外LED芯片的光输出功率达到了1.65 mW,对应的外量子效率为1.87%,饱和光输出功率达到4.31 mW.     

4H-SiC金属-半导体-金属结构紫外探测器的模拟与分析

用MEDICI软件对金属-半导体-金属(MSM)结构4H-SiC紫外(UV)探测器的I-V特性以及光谱响应等特性进行了模拟与分析,并探讨了金属电极的宽度、电极间距以及外延层厚度对探测器响应度的影响.结果表明,室温下该探测器的暗电流线性密度达到10-13A/μm,且在不同电压下光电流至少比暗电流大两个数量级;探测器的光谱响应范围为200~400 nm,在347 nm处响应度达到极大值;增大指宽或者减小指间距可以提高探测器的响应度;当波长小于峰值波长时外延层厚度对探测器的响应度基本没影响,而当波长大于峰值波长时随着外延层厚度的增大探测器的响应度有所增大.     

可用于极紫外光刻的三线毛细管的概念设计

极紫外光刻(EUVL)技术是目前193 nm浸没式光刻技术的延伸,有望突破30 nm或更小技术节点而成为下一代光刻(NGL)技术的主流。毛细管放电极紫外(EUV)光源可为极紫外光刻研究提供高效、便捷的光刻源头,但光源的辐射功率较低一直制约着极紫外光刻技术的发展。三线毛细管放电极紫外光源的概念设计与常用毛细管装置有着本质的区别,它们不同的工作机制将使三线毛细管放电产生的环带状等离子体极紫外光源的辐射功率明显高于常用毛细管的情形,最佳收集角也得到相应的提高。三线毛细管概念设计方案的提出不仅从技术上开拓出一片全新的领地,为极紫外光刻研究提供所需的光源,而且从效益上看更适合于大规模工业生产。     

Study on multiple receiver systems in non-line-of-sight ultraviolet communication systems

In this article, multiple receiver effects in a non-line-of-sight （NLOS） ultraviolet （UV） communication system is studied. The idea of using multiple receivers for diversity reception is known as a practical, effective and widely applied technique in wireless communications. The current approach is to use multiple antennas at the receiver in order to improve the quality of the received signal. A method of modeling and simulation is proposed to depict the principle and feasibility of the multiple receiver adopted in UV communication. The study provides an insight to the channel characteristics and achievable capabilities of ultraviolet communication systems with multiple receivers. It provides guidelines for practical system design with discussions on trade off between the receiver gain and the additional cost.     

GaN基p-i-n器件振动噪声研究

振动环境中,GaN基p-i-n器件的噪声会急剧增加,这限制了器件的探测能力。利用力锤和振动台分别模拟冲击振动和随机振动环境,研究了器件噪声在不同振动条件下的变化规律。实验结果表明,在冲击振动中,器件噪声呈现出周期特性,但噪声幅度随着时间减小。器件噪声主要的频率成分为429Hz,此频率下的器件噪声与激励力的大小、振动加速度的幅度成线性关系。随机振动的实验结果也表明,振动环境中测量到的噪声随着随机振动功率谱密度的增大而线性增加。