Prediction of retention time of phenols in liquid chromatography

The chromatographic behavior of phenols in reversed-phase mode liquid chromatography differs from that of non-ionic compounds such as alkyl alcohols, alkylbenzenes, halogenated benzenes, polyaromatic hydrocarbons, and aromatic acids. Therefore, the retention times of 61 phenols were measured in a system of an octadecyl bonded silica gel and acetonitrile/water mixtures. The logarithm of the capacity ratio (log k') was found to be a linear function of the hydrophobicity (log P) in acidic acetonitrile/water mixtures. This result was applied to a different octadecyl bonded silica gel. Eight phenols were selected as standard compounds, and their log k' values were measured in 0.05 M phosphoric acid in 10 to 90% acetonitrile/water mixtures. An empirical polynomial relation was obtained between the concentration of acetonitrile and the slope of the log k' vs log P curve. Finally the capacity ratio of all phenols were calculated in given eluents by the equations derived from the measurements of standard compounds and the calculated log P values. The difference between predicted capacity ratios and measured ones was within 10%.     

Finite time control of a class of nonlinear switched systems in spite of unknown parameters and input saturation

This article is devoted to the problem of robust stabilization of uncertain nonlinear switched systems with canonical structure. It is assumed that the constant parameters of the subsystems are unknown and cannot be adopted in the controller design. In addition, the dynamics of the subsystems are perturbed via modeling errors and external disturbances. The effects of unknown actuator saturation are compensated via proper adaptive control signals. The derived controller is based on the terminal sliding mode theory and does not need any prior knowledge about the bounds of the lumped uncertain terms. It is proved that once the system states reach the prescribed sliding manifold in a finite time interval, the whole system becomes insensitive to both the lumped uncertainties and the switching dynamics of the system. The common assumption of having known quadratic Lyapunov functions for the subsystems is relaxed and the derived adaptive approach does not force any limitation on the switching signal of the system. Subsequently, non-conservative conditions are provided to guarantee the global finite time bounded stability of the equilibrium state for the overall uncertain nonlinear switched system under arbitrary switching signals. A numerical computer simulation demonstrates the robust performance of the proposed controller.     

Alternating Current Electrohydrodynamics Induced Nanoshearing and Fluid Micromixing for Specific Capture of Cancer Cells

We report a new tuneable alternating current (ac) electrohydrodynamics (ac‐EHD) force referred to as “nanoshearing” which involves fluid flow generated within a few nanometers of an electrode surface. This force can be externally tuned via manipulating the applied ac‐EHD field strength. The ability to manipulate ac‐EHD induced forces and concomitant fluid micromixing can enhance fluid transport within the capture domain of the channel (e.g., transport of analytes and hence increase target–sensor interactions). This also provides a new capability to preferentially select strongly bound analytes over nonspecifically bound cells and molecules. To demonstrate the utility and versatility of nanoshearing phenomenon to specifically capture cancer cells, we present proof‐of‐concept data in lysed blood using two microfluidic devices containing a long array of asymmetric planar electrode pairs. Under the optimal experimental conditions, we achieved high capture efficiency (e.g., approximately 90 %; % RSD=2, n=3) with a 10‐fold reduction in nonspecific adsorption of non‐target cells for the detection of whole cells expressing Human Epidermal Growth Factor Receptor 2 (HER2). We believe that our ac‐EHD devices and the use of tuneable nanoshearing phenomenon may find relevance in a wide variety of biological and medical applications.     

一种使用TE11为过渡模的TE01-HE11模式变换器设计

基于弯曲圆波导耦合理论和规则圆波导突变结构模式匹配法, 利用MATLAB软件编写的相关数值计算程序得到波导模式转换结构的优化参量, 最终使用CST软件对模型进行了仿真和验证.该系统主要由三部分组成: 一个TE01-TE01的过渡器, TE01-TE11和TE11-HE11的圆波导模式转换器.计算结果表明, 该TE01-HE11模式转换系统在24.13 GHz的频率有5%的带宽、转换效率超过了99%.计算结果、仿真结果和实物冷测结果是一致的.     

InGaAs/GaAs/AlGaAs应变量子阱激光器

优化设计了既能实现较小垂直方向远场发散角,又能降低腔面光功率密度的ＩｎＧａＡｓ／ＧａＡｓ／ＡｌＧａＡｓ应变层量子阱激光器,并计算了该结构激光器实现基横模工作的脊形波导结构参数。利用分子束外延生长了ＩｎＧａＡｓ／ＧａＡｓ／ＡｌＧａＡｓ应变量子阱激光器材料并研制出基横模输出功率大于１４０ｍＷ,激射波长为９８０ｎｍ的脊形波导应变量子阱激光器,其微分量子效率为０．８Ｗ／Ａ,垂直和平行结平面方向远场发散角分别为２８°和６．８°     

共面闭合断续节理岩体直剪强度特性研究

介绍了节理面和岩桥各自的抗剪强度机制,引入法向变形协调条件,基于Mohr-Coulomb理论,推导了共面闭合断续节理岩体的直剪强度公式。模型试验发现,剪切破坏面以拉剪复合破坏为主,同时岩块中伴随大量的拉张微裂隙。试样的强度和变形具有明显的阶段性,全应力应变曲线主要经历了线弹性增长、节理面错动、次生裂纹起裂稳态扩展、节理面贯通破坏和残余强度5个阶段。对比发现,理论计算结果与试验值吻合较好。     

用光学相关识别方法测量单模光纤的折射率分布和色散

介绍了一种测量单模光纤剖面折射率分布和色散的新方法－－光学相关识别方法。应用计算全息制作高斯－拉盖尔模的匹配滤波器，根据光学相关识别原理测出单模光纤场分布的展开系数，由此推得剖面折射率分布和色散，给出了实际测量结果。     

准光激励毫米波圆波导旋转TE6 2模式产生器

介绍了采用准光方法激励圆波导产生旋转TE6 2模式的设计原理、测试方法和实验结果。该模式产生器由毫米波光学系统和开放同轴波导谐振腔系统组成:毫米波光学系统由角锥喇叭天线、双曲面反射镜、抛物面反射镜、修正抛物面反射镜等部件组成;开放同轴波导谐振腔系统由开放同轴波导谐振腔、圆波导、测试辐射喇叭天线组成。通过网络分析仪和毫米波近场自动测试系统测试表明:该模式产生器在频率为96.4 GHz附近产生的圆波导旋转TE6 2模式的纯度达到97%。     

1维圆柱掺杂光子晶体的滤波性能

为了研究1维圆柱掺杂光子晶体的滤波性质,利用光波在1维圆柱掺杂光子晶体中径向受限的条件,推导出光波在1维圆柱掺杂光子晶体中各个模式满足的关系式,研究了TE波和TM波各模式的缺陷模随模式量子数和杂质光学厚度的变化规律。TE波和TM波的缺陷模频率都随模式量子数的增加而增大;同一模式TE波和TM波的缺陷模频率都随杂质光学厚度的增加而减小。利用缺陷模随模式量子数的变化规律可以实现多通道滤波,利用缺陷模随杂质光学厚度的变化规律可以实现调谐滤波。     

X波段过模弯曲圆波导TM01-HE11模式变换器研究

在波束波导和反射面天线的馈源应用中, 为了产生低副瓣且方向图等化的高斯波束, 需要将高功率微波转换为准高斯模HE₁₁模辐射. 本文利用弯曲圆波导可同时从TM₀₁模产生TE₁₁模和TM₁₁模的原理, 提出了采用双弯曲过模圆波导结构直接将TM₀₁转换为HE₁₁的模式变换器, 避免了常规微波领域中首先将TM₀₁转换为TE₁₁再用波纹式或半径渐变式TE₁₁-HE₁₁转换器转换为准高斯波束功率容量不足或尺寸过长的不足. 基于模式耦合理论和Taguchi优化算法对模式变换器的弯曲半径、相移直端长度及引入位置进行了优化, 使输出的TE₁₁和TM₁₁成一定比率, 以组成HE₁₁模式, 并对设计的模式变换器进行了全电磁波仿真分析, 结果表明输出波束的标量高斯含量在9.05–9.8 GHz范围内均高于99%, 理论功率容量可达4.5 GW. 关键词： 高功率微波 模式耦合理论 Taguchi优化算法 模式变换器