密胺-脲甲醛树脂合成工艺放大研究

以密胺－脲甲醛树脂合成的小试工艺条件为依据，完成了放大试验过程的工艺研究。研究结果与小试研究的工艺条件相吻合。     

An optical surface plasmon resonance biosensor for determination of tetanus toxin

Surface plasmon resonance (SPR) has been successfully applied for the simple, rapid, and label-free assay of various biomolecules. This assay evaluates a novel wavelength modulation SPR biosensor for the detection of tetanus toxin. The wavelength modulation SPR biosensor is designed based on fixing the incident angle of light and measuring the reflected intensities in the resonance wavelength range spanning 400-800 nm simultaneously. Tetanus toxin (TeNT), one of the most potent toxins known, is synthesized as a 150 kDa single polypeptide chain. The SPR biosensor has been shown to be capable of directly detecting concentration of tetanus toxin as low as 0.028 Lf ml⁻¹. Under selected experimental conditions, the SPR biosensor has a good reproducibility, sensitivity and reversibility. The results illustrate how wavelength modulation SPR biosensor can be used to detect biomolecular interactions.     

超临界流体萃取仪器的研制

本文报道了以国产原配件为基础，成功地研制了分析规模的超临界流体萃取仪器、并对仪器性能进行了全面考察，仪器性能稳定，重现性良好（ＲＳＤ＜３．１％），定量线性关系可靠，可满足定量萃取的要求。     

Simultaneous determination of traces of heavy metals by solid-phase spectrophotometry

A coupling sensitive solid phase spectrophotometric (SPS) procedure for determination of traces of heavy metals (Me-SPS) and multicomponent analysis by multiple linear regressions (MA), a simple methodology for simultaneous determination of metals in mixtures was inaugurated. The Me-SPS procedure is based on sorption of heavy metals on PAN-resin and direct absorbance measurements of colour product Me-PAN sorbed on a solid carrier in a 1-mm cell. This methodology (Me-SPS-MA) was checked by simultaneous determination of metals in synthetic mixtures with different compositions and contents of metals important in pharmaceutical practice: Zn, Pb, Cd, Cu, Co, and Ni. Good agreement between experimental and theoretical amounts of heavy metals is obtained from the recovery test (78.3–110.0%). The proposed method enables determination of particular metal ion at the ng mL⁻¹ level and it was successfully applied to the determination impurities from heavy metal traces in pharmaceutical substances (Cu in ascorbic acid, Pb in glucose, and Zn in insulin). The proposed procedure could be possible contribution to the development of pharmacopoeial methodology for a heavy metals test.     

微量元素锌在治疗Bell麻痹中的作用

为探讨急性早期应用补锌和综合疗法治疗Bell麻痹 ,将 1 5 8例Bell麻痹患者 ,随机分成两组 :(1 )补锌组 (补锌 +综合疗法 ) ;(2 )对照组 (单纯综合疗法 )。对其进行了观察对比治疗 ,同时检测了所有患者治疗前后自身对照发锌值 ,还对所有患者进行了定位诊断、面神经电反应测试、并对面肌功能进行评分。结果表明 ,对定位诊断其病变在D段、面肌功能评分在 1 1分以下、面神经无电反应患者 ,即使给予早期综合治疗 ,效果仍较差 ,而早期给予补锌加综合治疗效果优于对照组 ,其它段内患者治疗次数和治愈天数也均优于对照组。可见微量元素锌在发挥免疫应答、免疫调控中的重要作用     

Boundary scan test,test methodology,and fault modeling

The test technique called boundary scan test (BST) offers new opportunities in testing but confronts users with new problems too. The implementation of BST in a chip has become an IEEE standard and users on board level are the next group to begin thinking about using the new possibilities. This article addresses some of the questions about changes in board-level testing and fault diagnosis. The fault model itself is also affected by using BST. Trivial items are extended with more sophisticated details in order to complete the fault model. Finally, BST appears to be a test technique that offers a high degree of detectability on board level, but for diagnosis, some additional effort has to be made.     

Economic modeling of board test strategies

A long and deep recession, coupled with continuous competitive pressure to reduce costs, is forcing many companies to review their test strategies. Testing costs have become a more significant proportion of the overall manufacturing cost even though manufacturing yields have increased dramatically over the past ten or twelve years. This causes attention to be focused on testing costs as a key source of cost reduction. The increased use of DFT and the integration of design and test are very positive moves towards controlling testing costs but other methods employed can often backfire. The increased use of low priced testers is one such method. The pressure to reduce costs, higher process yields and exhortations that testing adds no value can lead the test engineering manager to take the cheap route. In reality this can often turn out to be an expensive decision. The only way to avoid expensive mistakes is to perform an economic analysis of the alternative courses of action. In most cases this is done, but not always in the right manner or with the necessary amount of detail to make the comparisons meaningful. This article discusses the need for effective cost analysis of test strategies and highlights some of the pitfalls.     

Comments on “Aliasing Properties of Circular MISRs”

The analysis of aliasing probability presented in a recent article, Aliasing Properties of Circular MISRs [1], is based on an error model that cannot adequately represent real circuits. We show why conclusions presented in [1] should not be used in practice, substantiating our claim with experimental results.This work was supported in part by grants from the Natural Sciences and Engineering Research Council of Canada and in part by the British Columbia Advanced Systems Institute     

Bayesian sequential reliability for Weibull and related distributions

Assume that the probability density function for the lifetime of a newly designed product has the form: [H(t)/Q()] exp{–H(t)/Q()}. The Exponential(), Rayleigh, WeibullW(, ) and Pareto pdf's are special cases.Q() will be assumed to have an inverse Gamma prior. Assume thatm independent products are to be tested with replacement. A Bayesian Sequential Reliability Demonstration Testing plan is used to eigher accept the product and start formal production, or reject the product for reengineering. The test criterion is the intersection of two goals, a minimal goal to begin production and a mature product goal. The exact values of various risks and the distribution of total number of failures are evaluated. Based on a result about a Poisson process, the expected stopping time for the exponential failure time is also found. Included in these risks and expected stopping times are frequentist versions, thereof, so that the results also provide frequentist answers for a class of interesting stopping rules.This research was supported by NSF grants DMS-8703620 and DMS-8923071, and forms part of the Ph.D. Thesis of the first author, the development of which was supported in part by a David Ross grant at Purdue University. The authors thank the editors and a referee for insightful comments and suggestions.     

纳秒脉冲激光清洗石化设备对清洗表面的影响

采用纳秒脉冲激光对石化设备普遍使用的20钢表面锈蚀层以及油污进行了激光清洗试验,通过正交实验法得到优化后的激光清洗工艺参数,在激光功率18 W,激光脉冲重复频率75kHz,扫描速度3 000mm/s的清洗工艺参数下可有效去除20钢表面的锈蚀层;在激光功率20 W,激光脉冲重复频率75 kHz,扫描速度2 250 mm/s的清洗工艺参数下可有效去除20钢表面附着的油污。分析了激光清洗前后材料表面形貌的变化,研究了激光清洗前后表面的显微硬度以及耐腐蚀性,结果表明：激光清洗可以在不改变材料的耐腐蚀性能的同时提升材料表面的显微硬度,从而达到理想的激光清洗效果。