Six new photolabile linkers for solid-phase synthesis. 1. Methods of preparation

In the synthesis of combinatorial chemical libraries on solid phase, there is a need to cleave the compounds from the solid support before the library can be tested for biological activity. It is advantageous to use linkers which will release the libraries by mild photolytic cleavage. We have developed six new linkers of the photosensitive α-methyl 2-nitrobenzyl type containing amino, hydroxy, bromo and methylamino groups, and also 4-nitrophenoxycarbonyl activated OH and NH₂ groups. This revised version was published online in August 2006 with corrections to the Cover Date.     

基于Web的参数化图形库系统UML模型

通过面向对象的技术对图形库系统进行分析。利用参数化方法在服务器端建立图形库参数化模型、参数表以及底层图形数据库实例,在客户端访问图形库,调用图形数据文件。使用统一建模语言建立图形库的UML模型。     

A comparative study of EDTA-gel derived BSCCO and Pb-BSCCO systems by thermoanalytical and X-ray diffraction techniques

Summary This paper deals with the first investigation concerning the thermal behaviour of Ni(II) complexes with ligands having biguanide moieties. The new complex [NiL(1)](ClO₄)₂·2.5H₂O (1) with the Schiff base resulted in [2+1] condensation of N,N-dimethylbiguanide with pentane-2,4-dione (L(1)) and the complex [Ni₂L(2)](ClO₄)₄ (2), with the Schiff base, L(2), resulted through the oxidative condensation of L(1) have been synthesized and characterised. The bonding and stereochemistry of the complexes have been characterized by IR and electronic spectra. The cyclic voltammograms show the characteristic waves for mononuclear and respectively binuclear Ni(II) complexes and indicate that both complexes exhibit catalytic effects on the CO₂ electrochemical reduction. The thermal behaviour provided confirmation of the complexes composition as well as the number and the nature of water molecules and the intervals of thermal stability. The different nature of the ligands generates a different thermal behaviour for complexes.     

数字图书馆中的仓储服务系统

数字图书馆以电子格式存储海量的多媒体信息并能对这些信息进行高效的操作，如检索、提供访问接口、信息保护等。文章介绍了数字图书馆中的仓储服务系统，它提供对分布式数字对象的持久保存、安全访问和管理。仓储服务系统的基本存储单元是数字对象，整个系统就是为了存储、访问、管理数字对象而设计的。     

数字图书馆存储系统的构建

随着计算机网络技术的迅猛发展，“数字图书馆”成为当前高校图书馆建设的发展方向。本文叙述了在建立“数字图书馆”网络系统过程中，常用的海量存储设备，以及为了实现对海量数据资源的存储、共享和快速访问，“数字图书馆”存储系统的构建方案。     

Novel Inorganic–Organic Hybrid Coordination Polymer [(C10H16N)3(Ag6I9)] n : Synthesis, Structure and Optical Limiting Effect

A novel 1-D organic–inorganic silver(I)-iodide coordination architecture [(C₁₀H₁₆N)₃(Ag₆I₉)] _n (1) (C₁₀H₁₆N⁺=N-butyl-2-methyl-pyridinium) templated by appropriate cation has been constructed and structurally and optically characterized. The inorganic moiety of 1 presents one-dimensional hackle chain arrangement that results from the edges-sharing of AgI₄ tetrahedrons. Static attracting interactions between organic counter cations and inorganic chains are presented and contribute to the crystal packing. The optical limiting experiment shows that the present polymer exhibits a large optical limiting capacity.     

基于Delphi的融合DLL中的窗口

提出了一种简单的方法将DLL中的窗口融合(嵌入)到其他应用程序或DLL的窗口中，使用本方法可以简便地实现具有强扩展性和升级能力的软件系统。     

Identification of chemical ingredients of peanut stems and leaves extracts using UPLC‐QTOF‐MS coupled with novel informatics UNIFI platform

Peanut stems and leaves have been used traditionally as both herbal medicines and special food in Asia. In this study, the main functional compounds of peanut stems and leaves extracts were identified using UPLC separation coupled to high resolution mass spectrometry (QTOF‐MS), and a traditional medicine library. Three different extraction solvents (ethyl acetate, petroleum ether and n‐butanol) were evaluated to prepare the extracts of peanut stems and leaves. A total of 283 chemical compounds were identified in peanut stems and leaves extracts, of which 207 compounds are tentatively new identifications in Genus Arachis. The integration of data acquisition and processing with the traditional medicine library provides a simple, efficient process to effectively facilitate the identification of chemical ingredients in complex natural product extracts. The integrated workflow for separation, detection and identification of functional compounds in natural products using UPLC/QTOF‐MS greatly improves productivity for development of traditional herbal medicines. Copyright © 2016 John Wiley & Sons, Ltd.     

Ordered porous thin films in electrochemical analysis

Recently, the field of highly-ordered mesoporous and macroporous thin films coated onto solid electrode surfaces has begun to receive attention due to their great interest for electrochemical analysis. This review highlights the features of both electricallyconducting and non-conducting organized layers, which are applicable to designing electrochemical sensors, and the methods applied to construct these novel nanomaterials.We emphasize methods based on use of self-assembled colloidal templates (e.g., surfactants or nanoparticles), around which the materials of interest are formed. We then describe their basic electrochemical behavior and discuss their possible use as electrochemical sensors and biosensors, mostly in the particular case of structured metallic layers, functionalized mesoporous silica films, and some other continuous three-dimensional ordered porous structures.     

Stereoselective synthesis of highly enantioenriched 3-methyl-2-cyclohexen-1-ones possessing an asymmetric quaternary carbon as C-4 or C-6: a sugar template approach

The 1,4-addition of the enolate generated from α-methylated acetoacetate incorporated at C-4 of methyl 6-deoxy-2,3-di-O-(tert-butyldimethylsilyl)-α-d-glucopyranoside to methyl vinyl ketone, followed by aldol condensation of the resulting 1,4-addition product under two base-mediated conditions, provided 4-O-functionalized d-glucose derivatives with high diastereoselectivity. These products install a 3-methyl-2-cyclohexen-1-one-4- (or -6-) carboxylic acid as the O-4 ester, in which C-4 or C-6 is an asymmetric quaternary carbon. Removal of the sugar template from those aldol condensation products provided synthetically useful 3,6-dimethyl-2-cyclohexen-1-one-6-carboxylic acid and 3,4-dimethyl-2-cyclohexen-1-one-4-carboxylic acid derivatives both in high enantioenriched forms.