Canady Cold Helios Plasma Reduces Soft Tissue Sarcoma Viability by Inhibiting Proliferation,Disrupting Cell Cycle,and Inducing Apoptosis: A Preliminary Report

Soft tissue sarcomas (STS) are a rare and highly heterogeneous group of solid tumors, originating from various types of connective tissue. Complete removal of STS by surgery is challenging due to the anatomical location of the tumor, which results in tumor recurrence. Additionally, current polychemotherapeutic regimens are highly toxic with no rational survival benefit. Cold atmospheric plasma (CAP) is a novel technology that has demonstrated immense cancer therapeutic potential. Canady Cold Helios Plasma (CHCP) is a device that sprays CAP along the surgical margins to eradicate residual cancer cells after tumor resection. This preliminary study was conducted in vitro prior to in vivo testing in a humanitarian compassionate use case study and an FDA-approved phase 1 clinical trial (IDE G190165). In this study, the authors evaluate the efficacy of CHCP across multiple STS cell lines. CHCP treatment reduced the viability of four different STS cell lines (i.e., fibrosarcoma, synovial sarcoma, rhabdomyosarcoma, and liposarcoma) in a dose-dependent manner by inhibiting proliferation, disrupting cell cycle, and inducing apoptosis-like cell death.     

星基增强系统接收机中的导航比特同步设计与性能仿真

星基增强系统(SBAS)中导航电文速率为500符号/秒,针对其弱信号时找导航比特边界难的特点,提出了基于最大似然算法的比特同步算法,给出了在SBAS接收机中比特同步的应用公式和实现方法,并进一步创新性地设计了包含有软判决和多次判决的比特同步综合流程;最后在多种导航比特分布的情形下,对最大似然比特同步算法进行了不同载噪比下的性能仿真,确认了此算法在接收信号很弱时仍然有效。     

软X射线多层膜的光学性质和优化设计

一、引言 X射线多层膜是X激光和X光学的重要元件。近几年,不论在理论上还是在技术上,都得到了较快发展。 从X光晶体衍射角度出发,X射线多层膜可看作超晶格一维人工晶体。从薄膜光学出发,X射线多层膜是一类光学薄膜。这种薄膜的膜层很薄,折射率都接近1,并存在一定的吸收。X     

Moisture Sensitive Smart Yarns and Textiles from Self‐Balanced Silk Fiber Muscles

Smart textiles that sense, interact, and adapt to environmental stimuli have provided exciting new opportunities for a variety of applications. However, current advances have largely remained at the research stage due to the high cost, complexity of manufacturing, and uncomfortableness of environment‐sensitive materials. In contrast, natural textile materials are more attractive for smart textiles due to their merits in terms of low cost and comfortability. Here, water fog and humidity‐driven torsional and tensile actuation of thermally set twisted, coiled, plied silk fibers, and weave textiles from these silk fibers are reported. When exposed to water fog, the torsional silk fiber provides a fully reversible torsional stroke of 547° mm^?1. Coiled‐and‐thermoset silk yarns provide a 70% contraction when the relative humidity is changed from 20% to 80%. Such an excellent actuation behavior originates from water absorption‐induced loss of hydrogen bonds within the silk proteins and the associated structural transformation, which are corroborated by atomistic and macroscopic characterization of silk and molecular dynamics simulations. With its large abundance, cost‐effectiveness, and comfortability for wearing, the silk muscles will open up additional possibilities in industrial applications, such as smart textiles and soft robotics.     

基于可信度累积的伪随机序列多项式估计算法

针对高阶误码条件下伪随机序列多项式估计算法效率不高、容错性能差等问题进行研究,提出一种基于可信度累积的多项式估计算法。该算法结合了基于二元序列迭代的BM算法和改进型Chase算法,利用序列软信息,在BM算法外部构建序列及多项式可信度集合,通过可信度累积实现估计。然后,利用本原多项式的二元域性质,通过缩小累积多项式规模,提高估计精度。仿真结果表明,该算法性能不受制于多项式抽头个数,在误码率为18%的条件下能够完成17阶m序列多项式估计。     

基于图像边缘信息的多小波阈值去噪方法

基于小波变换的图像去噪方法是小波应用较成功的一个方面,阈值大小的确定是该方法最终去噪效果好坏的一个决定性因素.基于图像边缘信息的多小波闽值去噪方法充分研究了信号与噪声在小波变换各分解层上的不同传播特性,在保留代表边缘信息的小波系数的基础上,对不同方向、不同分解层的小波系数分别选取最佳阈值处理.与Donoho等人提出的Visu shrink去噪方法相比,此方法提高了去噪后图像的峰值信噪比(PSNR),使图像更加清晰,去噪效果更好.     

脉冲等子体软X射线探测系统

研制了一种脉冲重复频率为１０Ｈｚ的激光等离子体软Ｘ射线源；设计并建立了以掠入射恒偏单色仪为基础的脉冲等离子体软Ｘ射线辐射测试系统。光源实验使用能量１０００ｍＪ（波长０．５３μｍ）的激光脉冲，聚焦在不同的金属靶上，使之离子化。这种高温等离子体产生的辐射包含了波长０．４～２０ｎｍ的软Ｘ光连续谱和迭加在其上的线谱。靶材有Ｍｇ、Ａｌ、Ｔｉ、Ｆｅ、Ｃｕ、Ｚｎ、Ｓｎ、Ｐｂ和Ｂｉ。得到了不同原子序数的靶材辐射的光谱分布特性。     

脉冲激光对CCD的软损伤技术研究

根据CCD的结构特点,研究分析了YAG脉冲激光对CCD的损伤及其损伤机制,开展了脉冲激光对CCD的软损伤实验,实验验证了光饱和及光饱和串音现象,并提出了光电对抗中可以利用CCD的光饱和串音现象实现干扰对方的光电传感系统的结论。     

一种基于小波变换的图像去噪算法

利用小波方法去噪,是小波分析应用于工程实际的一个重要方面。针对图像存在大量噪声的情况,阐述小波变换去除信号噪声的基本原理和方法。在综合考虑图像去噪平滑效果和图像的清晰程度的基础上,提出一种多方向多尺度的自适应小波去噪算法。通过试验数据验证了该算法的可行性和鲁棒性。实验结果表明该方法增强了图像的视觉效果。     

一种AMR语音编码器的VLSI设计及FPGA实现

AMR(自适应多速率)语音编码标准由于其低码率和高质量,在通信和多媒体领域得到广泛应用.针对AMR语音编码标准的算法特点,提出了一种"音频DSP软核+硬件加速器"的VLSI实现结构.这种结构能够有效地实现编码算法,同时达到低成本、低功耗的要求.综合后的电路在满足语音编码实时性的要求下能工作在50MHz频率以下,功耗仅有不到50mW,和78 k门的芯片面积.最后通过FPGA整体验证,证明这种方案是可行有效的.同时优化后的音频DSP软核和硬件加速器中的模块复用设计,使得本设计方案对G.7xx系列编码算法具有通用和可移植性.