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71.
Emrys A. Jones Nicholas P. Lockyer John C. Vickerman 《International journal of mass spectrometry》2007,260(2-3):146
Recent developments in desorption/ionisation mass spectrometry techniques have made their application to biological analysis a realistic and successful proposition. Developments in primary ion source technology, mainly through the advent of polyatomic ion beams, have meant that the technique of secondary ion mass spectrometry (SIMS) can now access the depths of information required to allow biological imaging to be a viable option.Here the role of the primary ion C60+ is assessed with regard to molecular imaging of lipids and pharmaceuticals within tissue sections. High secondary ion yields and low surface damage accumulation are demonstrated on both model and real biological samples, indicating the high secondary ion efficiency afforded to the analyst by this primary ion when compared to other cluster ion beams used in imaging. The newly developed 40 keV C60+ ion source allows the beam to be focused such that high resolution imaging is demonstrated on a tissue sample, and the greater yields allow the molecular signal from the drug raclopride to be imaged within tissue section following in vivo dosing.The localisation shown for this drug alludes to issues regarding the chemical environment affecting the ionisation probability of the molecule; the importance of this effect is demonstrated with model systems and the possibility of using laser post-ionisation as a method for reducing this consequence of bio-sample complexity is demonstrated and discussed. 相似文献
72.
After taking into account energy conservation and the particle’s self-gravitation interaction, Hawking radiation of the massive
particle as tunneling from Schwarzshild-anti-de Sitter black hole is studied by using Parikh-Wilczek’s semi-classical quantum
tunneling approach. Meanwhile, Hawking radiation as tunneling from the black hole is reexamined by developing Angheben–Nadalini–Vanzo–Zerbini
(ANVZ) covariant method to cover energy conservation and the particle’s self-gravitation interaction. Both the results perfectly
generalize those obtained by Parikh and Wilczek, and show that the tunneling rate is related to the change of Bekenstein-Hawking
entropy, and the factual emission spectrum is not exactly thermal, but satisfies the underlying unitary theory.
PACS: 04.70-s, 9760. Lf. 相似文献
73.
挖坑机钻头主轴纵向振动系统模型的建立与控制 总被引:1,自引:0,他引:1
首先利用弹性杆理论和H am ilton变分原理建立了挖坑机钻头主轴及钻尖在工作过程中由于外激励的作用使钻尖与土壤互相作用而产生纵向振动的动力学模型,同时给出边界条件和初始条件.其次通过把系统外激励函数当作控制变量,利用Banach空间几何性质证明了此系统存在唯一最优控制元. 相似文献
74.
This paper overviews the electro-optical and thermal performances of different types of infrared detectors manufactured by
Sofradir. The detector’s fabrication processes and detector’s performance are shortly described. New staring arrays are more
compact and offer system solutions required by infrared market. Special attention is directed to some reliability advantages
of new dewar design. Finally, the development trends for highest resolution infrared detector are discussed.
The paper presented there appears in Infrared Photoelectronics, edited by Antoni Rogalski, Eustace L. Dereniak, Fiodor F. Sizov, Proc. SPIE Vol. 5957, 59570U (2005). 相似文献
75.
S. S. Banerjee S. Goldberg Y. Myasoedov M. Rappaport E. Zeldov A. Soibel F. de la Cruz J. van der Beek M. Konczykowski T. Tamegai V. Vinokur 《Pramana》2006,66(1):43-54
Disorder and porosity are parameters that strongly influence the physical behavior of materials, including their mechanical,
electrical, magnetic and optical properties. Vortices in superconductors can provide important insight into the effects of
disorder because their size is comparable to characteristic sizes of nanofabricated structures. Here we present experimental
evidence for a novel form of vortex matter that consists of inter-connected nanodroplets of vortex liquid caged in the pores
of a solid vortex structure, like a liquid permeated into a nanoporous solid skeleton. Our nanoporous skeleton is formed by
vortices pinned by correlated disorder created by high-energy heavy ion irradiation. By sweeping the applied magnetic field,
the number of vortices in the nanodroplets is varied continuously from a few to several hundred. Upon cooling, the caged nanodroplets
freeze into ordered nanocrystals through either a first-order or a continuous transition, whereas at high temperatures a uniform
liquid phase is formed upon delocalization-induced melting of the solid skeleton. This new vortex nanoliquid displays unique
properties and symmetries that are distinct from both solid and liquid phases. 相似文献
76.
直接成像技术在PCB中的应用 总被引:1,自引:0,他引:1
电子产品日趋小型化、轻量化、多功能化,使电路板线路密度增加,从而对电路板的制作技术有了更高的要求,普通的接触曝光成像技术不能满足高密度电路的要求,激光直接成像(LDI)技术正迎合了精细线路的要求,而在PCB制作中得到应用。介绍了LDI的成像原理、存在的优缺点及其在PCB制作中的应用。 相似文献
77.
鼻咽癌药物我成像定位仪的光学设计 总被引:9,自引:1,他引:8
对药物荧光鼻咽癌定位的光学系统进行理论分析,给出了该系统的光学设计方法和设计结果。光学系统设计包括,激光器出射光束与光纤高效率耦合技术,同光轴非接触两光纤间的光束耦合技术以及获得较好的像清晰度和衬度的技术。 相似文献
78.
79.
核磁共振成像一维空间编码教学实验 总被引:2,自引:2,他引:0
利用梯度磁场实现检测信号的空间编码,是核磁共振成像(MRI)的关键技术.本文采用ccc系列样品将二维问题简化为一维,使用超小型教学用核磁共振成像仪进行了一维空间编码实验研究,并对实验过程及实验结果进行了计算模拟和分析. 相似文献
80.