光生物调节作用研究进展

激光或单色光的强度可以分为低、中和高三个等级,其生物调节作用称为光生物调节作用。从内稳态的角度综述相应的研究进展。功能内稳态是维持功能充分稳定发挥的负反馈机制,它可以抵抗低于阈值的内外干扰,但被高于阈值的应激所打破。处于内稳态的应激称为成功应激,远离内稳态的应激称为慢性应激。成功应激打破一个功能内稳态之后,能够建立另一个功能内稳态。弱光可以调节慢性应激,但对成功应激或处于功能内稳态的功能无效。细胞的多种膜蛋白可以协同介导低强度单色光的自适应调节。内源性光敏剂介导中强度单色光的调节作用。弱光可以用于诊断功能内稳态或成功应激本身和其形成过程。并讨论了光生物调节作用在外科快速康复中的应用。     

A task oriented haptic gait rehabilitation robot

This paper presents the concept, design process, and the prototype of a novel haptics-based lower-extremity rehabilitation robot for bed-ridden stroke patients. This system, named Virtual Gait Rehabilitation Robot (ViGRR), is required to provide the average gait motion training as well as other targeted exercises such as leg press, stair stepping and motivational gaming, in order to facilitate motor learning and enable the training of daily activities such as walking and maintaining balance. The system requirements are laid out and linked to the design of a redundant planar 4DOF robot concept prototype. An iterative design optimization loop was setup to obtain the robot kinematic and dynamic parameters as well as the actuators. The robot’s mechanical design, model, safety features, admittance controllers, and the architecture of the haptic controller are presented. Preliminary experiments were planned and performed to evaluate the capability of the system in delivering task-based virtual-reality exercises and trajectory following scenarios.     

MATHEMATICAL MODELING AND EXPERIMENTAL STUDY ON SIT-TO-STAND PROCESS BASED ON ASSISTIVE STANDING-UP ROBOT

设计了一种符合人体起立运动的辅助起立机器人,通过牛顿欧拉方程对人体起立过程动力学进行分析与建模,推导机器人辅助起立、上肢辅助起立和肌力不足下肢辅助起立3种情况下,人体力与力矩平衡方程,依据方程在Simulink中建立仿真模型,并使用传感器系统对起立机器人辅助人体起立过程中力与力矩进行测量分析.结果表明：不论采取何种辅助起立方法,辅助起立机器人都可有效辅助起立,特别是对起立初始阶段辅助效果尤为明显.上肢辅助起立时,既可保持身体平衡与稳定,又可补偿起立时所需力与力矩,在接近完全站立时这种效果尤为明显,仿真模型可预测站立过程的关节力与力矩.肌力不足下肢参与辅助起立时,所提供辅助力有限但也起到一定作用.     

基于自适应按需辅助的上肢镜像控制策略

为了提高偏瘫患者在镜像康复训练过程中的主动性与系统抗干扰性,该文提出一种基于自适应按需辅助的上肢镜像控制策略.该策略主要包括镜像控制和自适应按需辅助控制两个模块,镜像模块采集健侧位置解算出患侧期望位置,与患侧实际位置比较得到位置偏差;按需辅助模块结合传统阻抗控制和一种患肢运动状态评估方法,自动实时调节对患肢的辅助力大小...     

Transition metal incorporated,modified bismuth oxide (Bi2O3) nano photo catalyst for deterioration of rosaniline hydrochloride dye as resource for environmental rehabilitation

The work presented here deals with the fabrication of bare Bi₂O₃ and modified Bi₂O₃ photocatalyst. The Bi₂O₃ material was modified with selected transition metals Co²⁺, Ni²⁺ with the 1% and 3% atomic weight percent insitu doping method via co-precipitation strategy. These three catalysts were successfully utilized for the waste water purification via photocatalytic degradation route. These all fabricated materials were precisely characterized by characterization techniques such as XRD, SEM, TEM, BET, IR and UV-DRS. The characterization techniques reveal the successful synthesis of material and effective modification of bismuth oxide lattice. Since, surface area for modified Bi₂O₃ was found to be enhanced in comparison to the bare Bi₂O_3, as well as declined band gap energy for modified Bi₂O₃ clearly indicates the successful doping of Co²⁺, Ni²⁺ metals. The bare Bi₂O₃ and modified Bi₂O₃ catalyst were employed for photocatalytic degradation of cationic dye R-HCl dye. The modified Bi₂O₃ found to be excellent over degradation efficiency of R-HCl with almost 97% of dye degradation in comparison to the bare Bi₂O_3. Reactive oxygen species experiment demonstrate that the addition of isopropyl alcohol (IPA), benzoquinone (BQ) and EDTA found to be successful to quench ^.OH, O₂^.- and h⁺ in photocatalysis mechanism. Additionally, the modified Bi₂O₃ was employed for phenol molecule degradation to investigate the possible excitation of this molecule under visible light irradiation.     

Relationship between first mobilization following the onset of stroke and clinical outcomes in patients with ischemic stroke in the general ward of a hospital: A cohort study

Objective: The purpose of this study was to compare the effects of first mobilization following a stroke with independently performing the activities of daily living at discharge in acute phase ischemic stroke patients in a general ward of a hospital. Methods: A total of 158 patients with ischemic strokes were admitted to a general ward from June 1, 2014 to March 31, 2015. Of the 158 patients, 53 met the study''s eligibility criteria. First mobilization was defined as the transfer of a patient from the bed to a wheelchair by a rehabilitation therapist. A favorable primary outcome at discharge was defined as a modified Rankin Scale score of < 3. The outcome was analyzed using the proportional hazards analysis and receiver operating characteristic curves. Results: The age of the participants was 78.2 ± 11.7 years, stroke severity evaluated by the National Institutes of Health Stroke Scale scores on admission was 14.3 ± 10.6 points, and first mobilization of this population was 6.4 ± 5.2 days. Thirteen [25%] patients had a favorable outcome. Hazards analysis showed a favorable outcome due to first mobilization (adjusted hazards ratio 0.80, 95% confidence interval 0.65-0.98; p < 0.05). The cutoff point for first mobilization to produce a favorable outcome was 6.5 days after the stroke onset (area under the curve 0.729; p < 0.05). Conclusion: As seen in stroke units, early first mobilization is associated with improved clinical outcomes in ischemic stroke patients admitted to a general ward.     

早期功能锻炼对乳腺癌患者术后康复影响的研究

为探讨早期功能锻炼对乳腺癌患者术后肢体功能的影响,对120例行早期功能锻炼的乳腺癌患者术后患者及66例未行早期功能锻炼的乳腺癌术后患者的临床资料进行了回顾性对照分析。结果表明,早期功能锻炼组患者上肢功能障碍的发生率明显低于对照组(P<0.05)。提示乳腺癌患者术后进行早期功能锻炼,可明显降低上肢功能障碍的发生率,明显改善患者的生活质量。     

基于Kinect体感器的康复机械手臂系统算法设计与实现

设计实现一种新的机械手臂康复系统。利用Kinect体感器获取人体右肩、右肘和右腕3个关节的三维坐标,计算得出所需控制参数。建立体感器与机械手臂之间通信机制,通过数据反馈调整所需控制参数。实现多自由度同时协调运动的康复型机械手臂控制方法。实验表明,该系统控制下的机械手臂能够平滑无明显停顿感地模仿人类手臂的自然动作,提高患者使用时的舒适度,增强康复效果。     

Progression‐Preserving Dimension Reduction for High‐Dimensional Sensor Data Visualization

This letter presents Progression‐Preserving Projection, a dimension reduction technique that finds a linear projection that maps a high‐dimensional sensor dataset into a two‐ or three‐dimensional subspace with a particularly useful property for visual exploration. As a demonstration of its effectiveness as a visual exploration and diagnostic means, we empirically evaluate the proposed technique over a dataset acquired from our own virtual‐reality‐enhanced ball‐intercepting training system designed to promote the upper extremity movement skills of individuals recovering from stroke‐related hemiparesis.