The impact of LIMS design and functionality on laboratory quality achievements

 A laboratory information management system (LIMS) can make a major contribution to the quality and therefore to the efficiency and competitiveness of a laboratory. Since it can impact all aspects of a laboratory's organization it must be the key if not the principal player of the laboratory's quality system. It should support the laboratory in establishing, maintaining and applying quality procedures thereby enabling the laboratory to achieve its quality goals. As a tool, LIMS permits the laboratory to input and use its own know-how and experience to optimize the total organization (internal and external) and workflow of generated information. However, perceived "quality" in the context of an LIMS, can be viewed as being made up of different facets such as the security, reliability and accessibility of information as well as its turn around time and production cost. This paper reviews the role of a LIMS in the laboratory and the contribution that both system design and functionality can have on "building quality ". Received: 5 October 1998 · Accepted: 20 October 1998     

Quantitative characterization of the global electrophilicity pattern of some reagents involved in 1,3-dipolar cycloaddition reactions

The global electrophilicity power, ω, of a series of dipoles and dipolarophiles commonly used in 1,3-dipolar cycloadditions may be conveniently classified within a unique relative scale. The effects of chemical substitution on the electrophilicity of molecules have been evaluated using a representative set of electron-withdrawing and electron-releasing groups for a series of dipoles including nitrone, nitrile oxide and azide derivatives. The absolute scale of electrophilicity is used to rationalize the chemical reactivity of these species as compared to the static reactivity pattern of the reagents involved in the Diels-Alder reactions.     

Quality assurance in research laboratories

During the last decade, it has become increasingly important that researchers demonstrate that research is conducted to the highest standards. The implementation of quality assurance for research laboratories will enable all fields of research and development to be judged impartially. There are no specific standards for research laboratories but where possible, existing standards can be adapted. This review is structured around two approaches. The first considers research to be a logical extension of testing, and it is assumed that testing standards can be applied methodically to each step in a research project. The second advocates a flexible approach, with research-specific criteria for assessing quality. The important papers published on this topic have been reviewed. The conclusions are that the general quality management approach, encompassed by the ISO 9000 series of standards with the emphasis on customer satisfaction and ‘fitness for purpose’, is suitable for implementing quality assurance in research laboratories.     

The European Eco-Management and Audit Scheme Accreditation – an overview

 Environmental quality is still deteriorating in the EU and worldwide despite all the Directives and Regulations in this field over the past 20 years. The European Community has devised a new approach to this problem with the introduction of the Eco-Management and Audit Scheme Regulation. This Regulation provides industry with an opportunity to demonstrate that it can achieve continuous improvement in its environmental performance through a voluntary scheme which is not based on the traditional command and control mechanisms of Directives. This paper gives an overview of the steps involved in implementing the European Eco-Management and Audit Scheme and the role of accreditation in supporting the scheme.     

基于物联网的医用耗材智能屋管理系统

针对医用高值耗材种类繁多、管理难度大的问题,为减少人力成本、提高医用高值耗材的智能化管理水平。本文提出了基于物联网的高值医用耗材智能屋的管理系统,介绍了智能屋的整体架构、系统功能、核心业务及流程设计,主要分为结构模块、RFID模块、数据库模块、控制系统模块四大模块,具体有用户管理、出入库管理、综合查询、预警管理四大业务,通过GM(1,1)模型对2022年全年高值医用耗材的月消耗量进行预测分析,并且检验得该预测模型的精度等级为一级,模型预测效果很好,能够为医院采购人员采购提供了一个参考,避免因过度的主观估计而造成的耗材浪费。该系统能够有效地提高医院对于高值医用耗材的管理水平,减少人力、物力和财力的消耗,为广大患者提供更加优质的医疗服务。本文所提的高值医用耗材智能屋管理系统解决了传统的高值医用耗材管理的诸多难题。     

毗邻沙漠地区微分博弈模型与宏观环境治理策略研究

工业化发展导致了脆弱的土地进一步沙漠化,沙漠地区政府应综合考虑经济发展与土地沙漠化导致的生态质量降低。通过构建两个沙漠化地区微分博弈模型,研究了两个地区的沙漠治理问题。研究结果表明,提高工业生产排放技术或沙漠治理技术均能够提高均衡经济产出水平,在工业生产收益系数较高的情况下也能够提高沙漠治理投入水平,并且两种技术提高存在交互效应;只有对生产排放技术水平和沙漠治理技术水平较高的地区,延长地方政府领导任期有利于沙漠治理;实现沙漠完全治理情况下控制土地再沙化的治理投入低于控制沙漠稳定在一定规模的治理投入。     

区块链技术影响下的供应链系统动态响应性研究

为解决供应链系统中信息时滞和不对称问题,加快推动区块链技术在供应链管理中的创新发展,本文运用控制理论构建由分销商和零售商组成的二级供应链系统控制模型,引入区块链技术影响下的信息校正因子,推导系统的传递函数,通过MATLAB仿真不同需求信号下的订单可变性和库存波动。仿真结果表明:(1)区块链技术的应用提高了库存系统的精准性和稳定性;(2)高库存可变性伴随着高订单可变性;(3)指数平滑系数和区块链技术影响下的信息校正因子有效抑制供应链中的牛鞭效应;(4)信息延迟时间越长,区块链技术影响下的信息校正因子对控制系统的抑制作用越显著。本研究量化了区块链技术对供应链中牛鞭效应的影响,提高了供应链系统的精准性和稳定性,丰富了区块链技术在供应链管理中的应用,为企业管理者提供新的研究思路。     

Products and transforms of white-noise functionals (in general setting)

Some sharp results about Weiner and Wick products of whitenoise functionals are obtained. Using the inequality of Wick products we show to what extent scaling transformations, translations, and Sobolev differentiations can be performed on white-noise functionals.This work was supported by the National Natural Science Foundation of China. This paper is an enlargement and revised version of the paper entitled Products and Transforms of White-Noise Functionals (preprint, 1990).     

PLC-RF无线传输网络中的能效最优设计方法

针对电力线通信（PLC）和射频（RF）无线通信混合传输的室内通信场景,提出了一种基于角度信息的信道状态信息（AI-CSI）的能效优先传输方案。首先,Wi-Fi无线网络和PLC网络分别作为主网络和次级网络,并且采用认知无线电技术来提高频谱效率的情况下,建立次级网络总能效最大化为目标函数的优化问题。其次,为了求解该问题,通过基于AI-CSI的迫零波束成形方法,获得波束成形权矢量,并进一步提出Dinkelbach与拉格朗日乘子法相结合的优化方法,进行最优的功率分配。最后,计算机仿真结果不仅验证了所提方案的有效性和优越性,而且分析了中继天线数和用户个数等典型参数对系统能效带来的影响,从而为实际系统设计提供了参考和依据。     

InPBi禁带下红外光致发光效率的Bi组分依赖研究

稀Bi半导体InPBi的光致发光（Photoluminescence, PL）主要来自缺陷能级跃迁过程,具有红外长波长、大线宽和高辐射强度等特点,因而引发广泛兴趣。针对InPBi的红外发光效率问题,本文研究了不同Bi组分InPBi的激发功率依赖红外PL光谱演化规律。实验发现,随着Bi组分增大,PL线型发生显著变化,导致发光波长总体红移;同时激发功率依赖的PL积分强度演化分析表明,发光效率随Bi组分先增大然后下降,在0.5%组分时发光效率达到峰值。发光效率增大一方面归因于Bi捕获空穴降低非辐射复合,另一方面来自Bi的表面活性剂效应;而高Bi组分引入过多缺陷从而抑制了Bi的优势,导致发光效率下降。这些结果或有助于理解InPBi的红外发射性能,表明InPBi具有红外光电子应用前景。