A regularised boundary element formulation for contactless SAR evaluations within homogeneous and inhomogeneous head phantoms

This work presents a Boundary Element Method (BEM) formulation for contactless electromagnetic field assessments. The new scheme is based on a regularised BEM approach that requires the use of electric measurements only. The regularisation is obtained by leveraging on an extension of Calderón techniques to rectangular systems leading to well-conditioned problems independent of the discretisation density. This enables the use of highly discretized Huygens surfaces that can be consequently placed very near to the radiating source. In addition, the new regularised scheme is hybridised with both surfacic homogeneous and volumetric inhomogeneous forward BEM solvers accelerated with fast matrix–vector multiplication schemes. This allows for rapid and effective dosimetric assessments and permits the use of inhomogeneous and realistic head phantoms. Numerical results corroborate the theory and confirms the practical effectiveness of all newly proposed formulations.     

Comparison of criteria used to access carcinogenicity in CPANN QSAR models versus the knowledge-based expert system Toxtree

The primary goal of this study was to describe and compare the criteria used to assess carcinogenic activity. The statistically-based predictive quantitative structure–activity relationship (QSAR) models based on the counter propagation artificial neural network (CPANN) algorithm, and knowledge-based expert systems based on a decision tree structural alert (SA) approach (Toxtree application), were considered. The integration of the QSAR (CPANN models) and SAR (Toxtree SA application) approach contributed to the mechanistic understanding of the QSAR model considered. The mapping technique inherent to CPANN Kohonen enables us to relate the similarities or dissimilarities within a congeneric set of chemicals with particular SAs for carcinogenicity. The focus of our investigations was the similarities and dissimilarities of the features used in the QSAR and SAR methods. Due to the complexity of the carcinogenic endpoint, the integration of different approaches allows the models to be improved and provides a valuable technique for evaluating the safety of chemicals.     

An Update on Synthesis of Coumarin Sulfonamides as Enzyme Inhibitors and Anticancer Agents

Coumarin is an important six-membered aromatic heterocyclic pharmacophore, widely distributed in natural products and synthetic molecules. The versatile and unique features of coumarin nucleus, in combination with privileged sulfonamide moiety, have enhanced the broad spectrum of biological activities. The research and development of coumarin, sulfonamide-based pharmacology, and medicinal chemistry have become active topics, and attracted the attention of medicinal chemists, pharmacists, and synthetic chemists. Coumarin sulfonamide compounds and analogs as clinical drugs have been used to cure various diseases with high therapeutic potency, which have shown their enormous development value. The diversified and wide array of biological activities such as anticancer, antibacterial, anti-fungal, antioxidant and anti-viral, etc. were displayed by diversified coumarin sulfonamides. The present systematic and comprehensive review in the current developments of synthesis and the medicinal chemistry of coumarin sulfonamide-based scaffolds give a whole range of therapeutics, especially in the field of oncology and carbonic anhydrase inhibitors. In the present review, various synthetic approaches, strategies, and methodologies involving effect of catalysts, the change of substrates, and the employment of various synthetic reaction conditions to obtain high yields is cited.     

Power-aware routing based on DSR for Mobile Ad hoc NETworks

Energy consumption is a crucial design concern in Mobile Ad hoc NETworks （MANETs） since nodes are powered by batteries with limited energy, whereas Dynamic Source Routing （DSR） protocol does not take the energy limitation of MANET nodes into account. This paper proposes an energy-saving routing algorithm based on DSR： Power Aware Routing protocol based on DSR （PAR-DSR）. The design objective of PAR-DSR is to select energy-efficient paths. The main features of PAR-DSR are： （1） Nodes use the Signal Attenuation Rate （SAR） to conduct power control operations; （2） Minimum path cost as metric to balance the traffic and energy consumption of wireless nodes. The simulation results show that PAR-DSR can greatly reduce the energy consumption of MANET nodes. The average node lifetime of PAR-DSR is 50%-77% longer than that of DSR.     

New method of formation design for both GMTI and InSAR using distributed satellites

This letter proposes a method for designing a specific formation of satellites where the flying motion only exists in a circle orbit plane of the reference satellite, which means that the orbit eccen- tricity is zero. This method combines the Hill equation, the Kepler equation, and the geometrical meaning of orbit elements. It creates the redundancy condition to simplify the deducing process, utilizes multiple conditions to solve the orbit elements for the satellite formation, and obtains the analytical relationship of the orbit elements for the formation satellites with the formation parameters and the orbit elements of the reference satellite. Using these formulations, the orbit elements and formation parameters for the formation satellites can be solved for the given orbit elements of the reference satellite. The letter describes the proposed double-ellipse formation for both GMTI and InSAR, and the validity of the formation is demonstrated via simulation.     

Algorithm of SAR satellite attitude measurement using GPS aided by kinematic vector

In this paper,in order to improve the accuracy of the Synthetic Aperture Radar (SAR) satellite attitude using Global Positioning System (GPS) wide-band carrier phase,the SAR satellite attitude kinematic vector and Kalman filter are introduced.Introducing the state variable function of GPS attitude determination algorithm in SAR satellite by means of kinematic vector and describing the observation function by the GPS wide-band carrier phase,the paper uses the Kalman filter algorithm to obtian the attitude variables of SAR satellite.Compared the simulation results of Kalman filter algorithm with the least square algorithm and explicit solution,it is indicated that the Kalman filter algorithm is the best.     

一种SAR ADC电容失配自测量与数字校准技术

为了解决高分辨率逐次逼近模数转换器(SAR ADC)中,电容式数模转换器(DAC)的电容失配导致精度下降的问题,提出了一种电容失配自测量方法,以及一种可适用于各种差分电容DAC设计的低复杂度的前台数字校准方法。该方法利用自身电容阵列及比较器完成位电容失配测量,基于电容失配的转换曲线分析,对每一位输出的权重进行修正,得到实际DAC电容大小对应的正确权重,完成数字校准。数模混合电路仿真结果表明,引入电容失配的16位SAR ADC,经该方法校准后,有效位数由10.74 bit提高到15.38 bit。     

多相位中心SAR虚假目标成对回波定位与强度研究

建立了多相位中心SAR在欠采样和非均匀采样状况下工作的回波数学模型,推导了其成像压缩结果的数学表达式.分析了"欠采样"成对回波和"速度失配"成对回波的形成机理,给出了成对回波定位和强度的通用计算公式.最后给出的仿真验证了本文结论的正确性.     

一种Ku波段行波管发射机的设计

介绍了一种Ku波段行波管发射机的技术参数及其设计方法。主要叙述了系统中高压电源、监控电路和调制器的设计,并针对发射机在无人机载SAR方面的应用,就如何解决体积小、重量轻情况下的电磁兼容问题,低气压条件下的高压绝缘与散热矛盾作了较详细说明。