Transverse Wave Propagation in Relativistic Two-Fluid Plasmas around Reissner–Nordström Black Hole

We investigate transverse electromagnetic waves propagating in a plasma influenced by the gravitational field of the Reissner–Nordström black hole. Applying 3+1 spacetime split we reformulate the relativistic two-fluid equations to take account of gravitational effects due to the event horizon and describe the set of simultaneous linear equations for the perturbations. Using a local approximation we investigate the one-dimensional radial propagation of Alfvén and high frequency electromagnetic waves. We derive the dispersion relation for these waves and solve it for the wave number k numerically.     

Hadron production and phase changes in relativistic heavy-ion collisions

We study soft hadron production in relativistic heavy-ion collisions in a wide range of reaction energy, 4.8 GeV < < 200 GeV, and make predictions about yields of particles using the statistical hadronization model. In fits to experimental data, we obtain both the statistical parameters as well as physical properties of the hadron source. We identify the properties of the fireball at the critical energy threshold, 6.26 GeV < < 7.61 GeV, marking for higher energies the hadronization of an entropy-rich phase. In terms of the chemical composition, one sees a phase which at low energy is chemically under-saturated, and which turns into a chemically over-saturated state persisting up to the maximum accessible energy. Assuming that there is no change in physical mechanisms in the energy range 15 > ≥200 GeV, we use continuity of particle yields and statistical parameters to predict the hadron production at = 62.4 GeV, and obtain total yields of hadrons at = 130 GeV. We consider, in depth, the pattern we uncover within the hadronization condition, and discuss possible mechanisms associated with the identified rapid change in system properties at . We propose that the chemically over-saturated 2 + 1 flavor hadron matter system undergoes a 1st-order phase transition.     

Effect of electron inertia on large amplitude solitary waves in presence of kinematic viscosity in dusty plasma

Nonlinear dust acoustic solitary waves in a dusty plasma are studied for nonzero kinematic viscosity. Sagdeev’s potential can be obtain upto any order in ϕ. The existence of soliton solution is determined by pseudopotential approach. It is seen that the electron inertia has a significant effect on the existence of solitary waves in presence of kinematic viscosity.     

Applications of photocatalytic titanium dioxide-based nanomaterials in sustainable agriculture

Photocatalytic materials are attracting attention as emerging resources for agricultural applications. This timely review assesses the current developments in the use of biocompatible titanium dioxide (TiO₂)-based photocatalytic nanomaterials (TiO₂-PN) as models to unravel agricultural growth, harvest, and post-harvest problems. Such developments can lead to technological innovations aimed at addressing the pressing global environmental challenges faced by farming. TiO₂-PN have been used as antimicrobial, growth-regulating, and fertilizer-like agents. The promising agricultural research applications of TiO₂-PN are highlighted along with a discussion of the main challenges that will need to be overcome to fully understand the roles of TiO₂-PN in the sustainable and productive exploitation of land and water for agricultural applications under natural conditions. In particular, rhizosphere internalization, translocation, and plant bioaccumulation pathways of photocatalytic materials from environmental exposition are outlined to illustrate the effect of TiO₂ on the agricultural cycle. Nanotoxicology and regulations are also discussed to illustrate the importance of biocompatibility and green synthesis of nanomaterials for safe use in real applications. This overview is focused on motivating and intensifying our understanding of on-site agricultural studies. Complementary biological approaches and structural damage observed by biological transmission electron, scanning electron, and optical microscopies should accelerate the practical contribution of TiO₂-PN to sustainable agriculture in conjunction with plant factories and plasma nitrogen fixation technology. Loadings below 10 μg/L of TiO₂-PN with a size of 40 nm benefit seed germination and root elongation as well as partially suppressing metal root translocation. However, only approximately 5% of current studies were carried out in real agricultural settings.     

A plasma-fluid model for EHD flow in DBD actuators and experimental validation

A numerical method to simulate plasma induced electrohydrodynamic flow is proposed in this study. The numerical model consists of three components. Firstly, a potential module to simulate temporal potential and electric field generated in the ionized fluid. Secondly, a plasma module to simulate plasma development and charge particle densities. Finally, a fluid module to simulate the flow affected by the body forces induced by the movement of the charged particles. Fluid flow is modeled using modified predictor-corrector strategy as proposed in the marker and cell method. The velocity field was corrected to achieve incompressible flow by calculating pressure correction factors, considered in all cells. Numerical convergence and time sensitivity analysis were carried to confirm grid independence and determine an efficient time step for simulations. Numerical computations are validated by comparing with experimental results of discharge currents and current densities. They were found to be in very good agreement thus providing an extensive validation. Furthermore, quiescent flow over a dielectric barrier discharge actuator is simulated in the this study, using the proposed plasma-fluid model, to model flow evolution and resolve temporal flow features for detailed analysis. The streamline and vorticity plots were analyzed and compared with experimental results, and flow results were found to be in-line with the experiments.     

A general analytical method for evaluation of the thermodynamic properties of matters using virial coefficients with Morse potential at high temperature

In this paper, we established an analytical formula for the second virial coefficient (SVC) with Morse potential without using any numerical methods, and the obtained formula is applied to the calculation of the speed of sound of some matter at high temperature. This approach is based on the series expansion formula and special functions, which allows the exact evaluations of any thermodynamic properties of matter using the SVC. As an application, the obtained analytical formula is used for evaluation of the SVC with Morse potential for high‐temperature gas and the plasma region of the intermolecular interactions of neutral atom gases of B, Si, Zn, H₂, N₂, O₂, NO, CO, He, Ne, Ar, Kr , and Xe . Based on the obtained formula of SVC, the speed of sound for gases of N₂, Ar , and Zn are also determined analytically. A specific maximum temperature is chosen for every gas to ensure that there are still neutral atoms in the gas, and low temperatures are avoided due to quantum effects. The results are compared with numerical data and another analytical data from the literature. The new analytical solution is shown to be in good agreement with the compared data and is verified to supply proper thermodynamic data.     

The thermophysical properties of low‐temperature Pb plasma

The thermophysical properties of low‐temperature Pb plasma are calculated at temperatures 10–100 kK and densities below 0.2 of the solid‐state value. The thermodynamic values (pressure and internal energy) and transport coefficients (electrical conductivity, thermal conductivity, and thermal power) are considered. The plasma composition and thermodynamic parameters are obtained within the chemical approach, namely by means of the solution of the corresponding system of the coupled mass action law equations. Atom ionization up to +4 is taken into consideration. The electronic transport coefficients are calculated within the relaxation time approximation. The results obtained by means of the present model are compared with the available data of other models and experiments.     

Quantification of fenoprofen in human plasma using UHPLC–tandem mass spectrometry for pharmacokinetic study in healthy subjects

A rapid, simple and sensitive ultra-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) method has been developed to quantify fenoprofen, a nonsteroidal anti-inflammatory drug in human plasma for a pharmacokinetic study in healthy subjects. Owing to high levels of protein binding, protein precipitation followed by solid-phase extraction was employed for the extraction of fenoprofen and fenoprofen-d3 (used as internal standard) from 200 μL human plasma. Separation was performed on a BEH C₁₈ (50 × 2.1 mm, 1.7 μm) column using methanol−0.2% acetic acid in water (75:25, v/v) under isocratic elution. Electrospray ionization was operated in the negative mode for sample ionization. Ion transitions used for quantification in the selected reaction monitoring mode were m/z 241/197 and m/z 244/200 for fenoprofen and fenoprofen-d3, respectively. Under the optimized conditions, fenoprofen showed excellent linearity in the concentration range 0.02–20 μg/mL (r² ≥ 0.9996), adequate sensitivity, favorable accuracy (96.4–103.7%) and precision (percentage coefficient of variation ≤4.3) with negligible matrix effect. The validated method was successfully applied to a pharmacokinetic study of fenoprofen in healthy subjects. The significant features of the method include higher sensitivity, small plasma volume for processing and a short analysis time.     

The development and validation of a novel LC–MS/MS method for the quantification of cenicriviroc in human plasma and cerebrospinal fluid

A high-performance liquid chromatography tandem mass spectrometric method was developed and validated for cenicriviroc (CVC) quantification in human plasma and cerebrospinal fluid (CSF). The method involved precipitation with acetonitrile and injecting supernatants onto the column. Separation was achieved on an XBridge C₁₈ column with a gradient elution of 0.1% formic acid in water and acetonitrile. Analyte detection was conducted in positive ion mode using selected reaction monitoring. The m/z transitions were: CVC (697.3 → 574.3) and CVC-d7 (704.4 → 574.3). Calibration curve ranged from 5 to 1000 ng/mL for plasma and from 0.241 to 15.0 ng/mL for CSF. The intra- and inter-day precision and accuracy were <15% for both plasma and CSF across four different concentrations. CVC recovery from plasma and artificial CSF was >90%. The method was utilized for the measurement of patients’ plasma and CSF samples taking a dose of 50, 150 and 300 mg q.d.     

Multiplexed therapeutic drug monitoring of antipsychotics in dried plasma spots by LC‐MS/MS

In this work, a convenient method for the therapeutic monitoring of seven common antipsychotic drugs in “dried plasma spot” samples has been developed. It is based on the liquid chromatography tandem mass spectrometry technique, operating in multiple reaction monitoring mode, and a straightforward procedure for the simultaneous extraction of all antipsychotics in a single step, with high extraction yield. The method was fully validated with proper accuracy, precision, selectivity and sensitivity, for all the drugs. Limits of quantification were 0.12, 1.09, 1.46, 1.47, 5.70, 1.32, 1.33 µg/L for haloperidol, aripiprazole, olanzapine, quetiapine, clozapine, risperidone, and paliperidone, respectively. Accuracy, intra‐ and interday precision values were <10% for all drugs at all concentration levels examined. The method was tested in the analysis of 30 plasma samples from real patients for each drug. The proposed analytical approach, by combining practical and logistical advantages of microsampling with liquid chromatography tandem mass spectrometry analytical performance, could offer an ideal strategy for accurate and timely therapeutic drug monitoring of antipsychotic drugs in most clinical settings, even in remote centers and/or in out‐patient settings, bringing so many potential improvements in psychiatric patient care.