Inclusion effects of cyclodextrins on the photobleaching of coumarins

The effects of cyclodextrins (-CD,-CD and-CD) on the photobleaching of coumarin 120 (7-amino-4-methylcoumarin) (1) and coumarin 151 (7-amino-4-trifluoromethylcoumarin) (2) have been investigated by spectrophotometric measurement. It is concluded that-CD and-CD decelerate the rates of photobleaching of1, whilst-CD accelerates the rate of2 and-CD has no effect on the rate of photobleaching of2.     

Effect of Lipid Phase State and Foam Film Type on the Properties of DMPG Stabilized Foams

The drainage and stability of DMPG (l-α-phosphatidyl-dl-glycerol dimyristoyl) foams were studied by a microconductivity method under conditions where three different foam film types could be formed—thin foam films (TFF), common black foam films (CBF), and Newton black foam films (NBF). Foaming properties were investigated at 20 and 28°C where DMPG is in the gel and liquid-crystalline states. Higher conductivity signals were observed at the higher temperature where DMPG was in the liquid-crystalline state, which is indicative of wetter or more stable foams under these conditions. This effect was observed independent of foam film type. However, for a given phase state, the type of foam films formed significantly influenced the stability and rate of drainage of the foam. Indeed, the water content of the foams, obtained under conditions for formation of different foam films, is ranked in the order TFF > CBF > NBF. When the temperature was increased to 28°C (i.e., in the liquid-crystalline state), CBF and NBF showed a slight decrease in film thickness and an increase in film lifetime and surface molecular diffusion coefficient in the adsorbed layer. It is likely that the fluidity of the interfacial layer is an important factor contributing to DMPG foam stabilization.     

光动力治疗用酞菁类光敏剂的合成研究进展

本文介绍了光动力治疗原理、酞菁类光敏剂的合成方法及其近年来得到的研究进展,并介绍了酞菁在光动力治疗中的光化学生物过程和光漂白现象,还对其存在的缺点和今后的研究方向进行了讨论.     

光漂白引起推拉型偶氮有机聚合物折射率变化的测量

本文主要研究了聚合物材料漂白引起的年射率变化的测量方法。通过光漂白在薄膜上形成折射率减小的区域,用探测光对该区域进行单光束扫描,由测量的归一化透过率得到薄膜的折射率变化。在实验上测量出了用Ar^ 激光作为漂白光源时6种系列偶氮化合物掺杂聚合物薄膜的折射率变化,实验结果具有较高的精确度。     

用光漂白法制备聚合物薄膜光栅耦合器

从理论和实验上研究了用光漂白的方法实现PMMA/DR1聚合物周期性波导,并制备了光栅耦合器。由辐射模的辐射角的变化求出了由光漂白引起的波导有效折射率的变化,并确定了所制备的周期性波导几个辐射模式的出射角。     

Novel Photobleachable Deep UV Resists Based on Single Component Nonchemically Amplified Resist System

Summary: Photobleachable deep UV resists were designed by introducing diazoketo groups in polymer side chains. The diazoketo groups undergo the Wolff rearrangement upon irradiation in the deep UV, affording ketenes that react with water to provide base‐soluble photoproducts. The polymers were synthesized by radical copolymerization of 2‐(2‐diazo‐3‐oxo‐butyryloxy)‐ethyl methacrylate, 2‐hydroxyethyl methacrylate, and γ‐butyrolacton‐2‐yl methacrylate. The single component resist showed 0.7 µm line and space patterns using a mercury‐xenon lamp in a contact printing mode.

Scanning electron micrograph of 0.7 µm line and space patterns printed with polymer B at a dose of 70 mJ · cm⁻².     

基于荧光漂白成像的润滑油膜剪切流速测量

沿润滑油膜厚度方向的剪切流速分布是影响机械部件润滑性能的重要因素.为此,搭建了基于荧光漂白成像的微间隙油膜剪切流速分布测量平台.通过对漂白区域形状演化过程进行图像分析,获得了微米量级间隙中的PB450和PAO6润滑油膜的剪切速度分布.结果表明:在设定测试条件下,厚度为8.5μm的PB450油膜沿膜厚方向的剪切流速近似为典型的线性分布,而相同厚度下的PAO6油膜流速分布表现为非线性塞流,界面附近油膜黏度较中层显著下降.研究还发现,同一滑动速度下,PAO6剪切流速偏离线性分布的程度随膜厚的降低而增加.经过比对分析,试验结果与流体动压润滑条件下的相关数据吻合.     

MALDI-TOF mass spectrometric analysis for the characterization of the 5,10,15,20-tetrakis- (m-hydroxyphenyl)bacteriochlorin (m-THPBC) photoproducts in biological environment

Photoproducts formation upon irradiation (739 nm) of 5,10,15,20-tetrakis(m-hydroxyphenyl)bacteriochlorin (m-THPBC) in phosphate buffer saline (PBS) supplemented with human serum albumin (HSA) were studied by means of absorption spectroscopy and MALDI-TOF mass spectrometry. The experiments were performed with a freshly prepared PBS-HSA solution of m-THPBC and with a PBS-HSA m-THPBC solution incubated for 6 h at 37 degrees C. The incubation of m-THPBC solution leads to the dye monomerisation, whereas in the freshly prepared solution, m-THPBC is under an aggregated form. Regardless of the incubation condition, photobleaching experiments carried out by absorption spectroscopy demonstrate the degradation of the photosensitizer and its phototransformation in m-THPC. Moreover, m-THPC was the sole photoproduct detected using absorption spectroscopy. Together with a degradation of m-THPBC and formation of m-THPC, MALDI-TOF mass spectrometry evidenced several other photoinduced modifications. Photoproducts such as dihydroxy m-THPBC and dihydroxy m-THPC were detected in both conditions; however, the formation of hydroxylated photoproducts was significantly greater in incubated solution. In addition, small molecules arising from the degradation of the photosensitizer and identified as dipyrin derivatives and dipyrrolic synthon were observed.     

Lateral mobility of plasma membrane proteins in dividing eggs of the loach (Misgurnus fossilis): Regional differences and changes during the cell cycle

Regional differences in lateral diffusion rates of fluorescence-labeled proteins have been studied in the plasma membrane of dividing eggs of the loach (Misgurnus fossilis) by fluorescence recovery after photobleaching (FRAP). Apparent animal-vegetal differences in fluorescence intensity, lateral diffusion coefficients, and fractions of mobile proteins have been found, with all these quantities being higher in the animal pole region than in the yolk region. Cyclic changes in protein diffusion coefficients and mobile fractions during the first few cell cycles have also been recorded. Soon after the end of a cleavage, the diffusion coefficient reaches its minimal value and increases rapidly before the next cleavage.     

Ge：SiO2的光敏缺陷的研究

研究了Ｇｅ；ＳｉＯ２光敏缺陷的特性，分别在４８８ｎｍＡｒ离子激光与１９３ｎｍＡｒ准分子激光作用下，由紫外吸收带，激光荧光的测量实验及电子自旋共振实验，发现光纤中５．１ｅＶ锗缺陷吸收带实验上是由５．０６ｅＶ可光致漂白带与５．１７ｅＶ不可漂白带组成；２９５ｎｍ的激发荧光与５．０６ｅＶ的缺氧锗缺陷对应，随５．０６ｅＶ缺陷吸收带的漂白而衰减；