全文获取类型
收费全文 | 6254篇 |
免费 | 808篇 |
国内免费 | 488篇 |
专业分类
化学 | 1338篇 |
晶体学 | 46篇 |
力学 | 1294篇 |
综合类 | 64篇 |
数学 | 1523篇 |
物理学 | 1643篇 |
无线电 | 1642篇 |
出版年
2024年 | 21篇 |
2023年 | 83篇 |
2022年 | 202篇 |
2021年 | 221篇 |
2020年 | 255篇 |
2019年 | 204篇 |
2018年 | 198篇 |
2017年 | 229篇 |
2016年 | 285篇 |
2015年 | 241篇 |
2014年 | 358篇 |
2013年 | 467篇 |
2012年 | 353篇 |
2011年 | 392篇 |
2010年 | 315篇 |
2009年 | 362篇 |
2008年 | 319篇 |
2007年 | 321篇 |
2006年 | 324篇 |
2005年 | 296篇 |
2004年 | 230篇 |
2003年 | 239篇 |
2002年 | 199篇 |
2001年 | 162篇 |
2000年 | 173篇 |
1999年 | 138篇 |
1998年 | 129篇 |
1997年 | 129篇 |
1996年 | 86篇 |
1995年 | 89篇 |
1994年 | 78篇 |
1993年 | 79篇 |
1992年 | 76篇 |
1991年 | 47篇 |
1990年 | 41篇 |
1989年 | 38篇 |
1988年 | 24篇 |
1987年 | 19篇 |
1986年 | 16篇 |
1985年 | 20篇 |
1984年 | 12篇 |
1983年 | 9篇 |
1982年 | 14篇 |
1981年 | 9篇 |
1980年 | 6篇 |
1979年 | 11篇 |
1978年 | 8篇 |
1972年 | 4篇 |
1971年 | 4篇 |
1957年 | 6篇 |
排序方式: 共有7550条查询结果,搜索用时 15 毫秒
61.
A. Pérez-González J. M. Vilar-Fernández W. González-Manteiga 《Annals of the Institute of Statistical Mathematics》2009,61(1):85-109
The main objective of this work is the nonparametric estimation of the regression function with correlated errors when observations
are missing in the response variable. Two nonparametric estimators of the regression function are proposed. The asymptotic
properties of these estimators are studied; expresions for the bias and the variance are obtained and the joint asymptotic
normality is established. A simulation study is also included. 相似文献
62.
63.
Although event-related fMRI is able to reliably detect brief changes in brain activity and is now widely used throughout systems and cognitive neuroscience, there have been no previous reports of event-related spinal cord fMRI. This is likely attributable to the various technical challenges associated with spinal fMRI (e.g., imaging a suitable length of the cord, reducing image artifacts from the vertebrae and intervertebral discs, and dealing with physiological noise from spinal cord motion). However, with many of these issues now resolved, the largest remaining impediment for event-related spinal fMRI is a deprived understanding of the spinal cord fMRI signal time course. Therefore, in this study, we used a proton density-weighted HASTE sequence, with functional contrast based on signal enhancement by extravascular water protons (SEEP), and a motion-compensating GLM analysis to (i) characterize the SEEP response function in the human cervical spinal cord and (ii) demonstrate the feasibility of event-related spinal fMRI. This was achieved by applying very brief (1 s) epochs of 22°C thermal stimulation to the palm of the hand and measuring the impulse response function. Our results suggest that the spinal cord SEEP response (time to peak ≈8 s; FWHM ≈4 s; and probably lacking pre- and poststimulus undershoots) is slower than previous estimates of SEEP or BOLD responses in the brain, but faster than previously reported spinal cord BOLD responses. Finally, by detecting and mapping consistent signal-intensity changes within and across subjects, and validating these regions with a block-designed experiment, this study represents the first successful demonstration of event-related spinal fMRI. 相似文献
64.
65.
The optical response time of a nematic liquid crystal (NLC) decreases due to incorporation of carbon nanotubes (CNTs) in the liquid-crystal host. Such reduction is believed to be due to an increase in the elastic constant of the nanotube-doped LC system. In this paper, we present the effect on optical response due to doping an NLC with octadecylamine functionalised single-walled carbon nanotubes (ODA-SWCNT) in a twisted alignment mode. The electro-optic switching amplitude of ODA-SWCNT nanocomposites of NLC decreases compared to pure NLC. A fast response time is observed with an increase in the concentration of ODA-SWCNT in NLC host. Additionally, optical response of pure NLC in a twisted nematic (TN) cell fabricated using mixtures of polyimide (PI) and ODA-SWCNT as an alignment layer is investigated. The optical response time decreased by ~75% in a TN cell fabricated with a mixture of PI and ODA-SWCNT compared to that of a TN cell prepared using a pure PI alignment layer. The presence of ODA-SWCNT in the alignment layer enhances the surface anchoring of the NLC molecules leading to an increase in the elastic constant and a decrease in the optical response time of NLC. 相似文献
66.
Jorge E. Navarro-Baez Luz María Martínez Jorge Welti-Chanes Gnesis V. Buitimea-Cantúa Zamantha Escobedo-Avellaneda 《Molecules (Basel, Switzerland)》2022,27(5)
Phenolic compounds from fruits and vegetables have shown antioxidant, anticancer, anti-inflammatory, among other beneficial properties for human health. All these benefits have motivated multiple studies about preserving, extracting, and even increasing the concentration of these compounds in foods. A diverse group of vegetable products treated with High Hydrostatic Pressure (HHP) at different pressure and time have shown higher phenolic content than their untreated counterparts. The increments have been associated with an improvement in their extraction from cellular tissues and even with the activation of the biosynthetic pathway for their production. The application of HHP from 500 to 600 MPa, has been shown to cause cell wall disruption facilitating the release of phenolic compounds from cell compartments. HPP treatments ranging from 15 to 100 MPa during 10–20 min at room temperature have produced changes in phenolic biosynthesis with increments up to 155%. This review analyzes the use of HHP as a method to increase the phenolic content in vegetable systems. Phenolic content changes are associated with either an immediate stress response, with a consequent improvement in their extraction from cellular tissues, or a late stress response that activates the biosynthetic pathways of phenolics in plants. 相似文献
67.
Noha M. Soliman Faiyaz Shakeel Nazrul Haq Fars K. Alanazi Sultan Alshehri Mohsen Bayomi Ahmed S. M. Alenazi Ibrahim A. Alsarra 《Molecules (Basel, Switzerland)》2022,27(14)
Various chitosan (CS)-based nanoparticles (CS-NPs) of ciprofloxacin hydrochloride (CHCl) have been investigated for therapeutic delivery and to enhance antimicrobial efficacy. However, the Box–Behnken design (BBD)-supported statistical optimization of NPs of CHCl has not been performed in the literature. As a result, the goal of this study was to look into the key interactions and quadratic impacts of formulation variables on the performance of CHCl-CS-NPs in a systematic way. To optimize CHCl-loaded CS-NPs generated by the ionic gelation process, the response surface methodology (RSM) was used. The BBD was used with three factors on three levels and three replicas at the central point. Tripolyphosphate, CS concentrations, and ultrasonication energy were chosen as independent variables after preliminary screening. Particle size (PS), polydispersity index (PDI), zeta potential (ZP), encapsulation efficiency (EE), and in vitro release were the dependent factors (responses). Prepared NPs were found in the PS range of 198–304 nm with a ZP of 27–42 mV. EE and drug release were in the range of 23–45% and 36–61%, respectively. All of the responses were optimized at the same time using a desirability function based on Design Expert® modeling and a desirability factor of 95%. The minimum inhibitory concentration (MIC) of the improved formula against two bacterial strains, Pseudomonas aeruginosa and Staphylococcus aureus, was determined. The MIC of the optimized NPs was found to be decreased 4-fold compared with pure CHCl. The predicted and observed values for the optimized formulation were nearly identical. The BBD aided in a better understanding of the intrinsic relationship between formulation variables and responses, as well as the optimization of CHCl-loaded CS-NPs in a time- and labor-efficient manner. 相似文献
68.
《中国化学快报》2020,31(8):2077-2082
The morphological and structural design provides an efficient protocol to optimize the performance of gas sensing materials. In this work, a gas sensor with high sensitivity for triethylamine (TEA) detection is developed based on p-type NiCo2O4 hierarchical microspheres. The NiCo2O4 microspheres, synthesized by a hydrothermal route, have a three-dimensional (3D) urchin-like structure assembled by nanorod building blocks. The structure-property correlation has been investigated by powder X-ray diffraction, X-ray photoelectron spectroscopy, transmission electron microscope, scanning electron microscope, N2 adsorption-desorption tests and comprehensive gas sensing experiments. The influence of calcination temperature on the morphological structure and sensing performances has been investigated. Results reveal that the material annealed at 300 °C has a very large specific surface area of 125.27 m2/g, thereby demonstrating the best TEA sensing properties including high response and low limit of detection (145 ppb), good selectivity and stability. The further increase of the calcination temperature leads to the collapse of the 3D hierarchical structure with significantly decreased surface area, which is found to decline the sensing performances. This work indicates the promise of ternary p-type metal oxide nanostructures for application in highly sensitive gas sensors. 相似文献
69.
Lead sulphide (PbS) nano-sculptured thin films (nSTFs) are prepared for the first time using glancing angle deposition technique by physical vapour deposition process. An anisotropic morphology is obtained, which provides an orientational effect. Due to this anisotropic nature of PbS nSTF an attempt has been made to check its effect on the alignment of nematic liquid crystals (LCs). Two different LC devices were fabricated, that is, anti-parallel aligned or electrically-controlled birefringence and hybrid twisted nematic. It is noticed that in both types of devices, good alignment is obtained with high extinction and contrast. A significant effect of these alignments on the electro-optic properties of the LC is reported such as the threshold voltage, response time and contrast ratio. 相似文献
70.
《Analytical letters》2012,45(15):2411-2429
Abstract A nickel(II) [Ni(II)] ion-selective electrode was prepared by incorporating a new N-S Schiff base ligand, glyoxal-bis(S-benzyldithiocarbazate) (GBSB), as a neutral carrier into the PVC matrix. The proposed electrode exhibits an excellent near-Nernstian response for Ni2+ ions, ranging from 2.8 × 10?7 to 1.0 × 10?1 mol/L with a detection limit of 1.2 × 10?7 mol/L and a slope of 31.9 ± 0.3 mV/dec in pH 4.0 nitrate buffer solution at 25°C. It has an appropriate response time and suitable reproducibility and can be used for at least 3 months. The operational pH range of the proposed electrode is 4.0–7.5. The response mechanism is discussed in view of the alternating current (AC) impedance technique. In addition, the electrode was successfully used as an indicator electrode in potentiometric titration of Ni2+ ion and in the direct determination of Ni2+ ion in milk power and chocolate samples. 相似文献