基于遗传算法构建巴耳末公式

基于遗传算法构建了巴耳末公式．通过建立合适的拟合数学模型，用计算机对数学模型进行优化，使之尽可能反映氢原子实际谱线分布，并求出经验常量和拟合公式，最后分析了所得结果．     

松弛型并行多分裂方法解非线性方程组的安全界

本文对某些非线性方程组F(x)=0,导出了一个算法,用它可以迭代建立F(x)=0的解的紧致上、下界。算法基于某些矩阵的多分裂,因此具有自然的并行性。我们证明了趋向于解的界之收敛原则,给出了参数的收敛性区域并考察了方法的收敛速度。     

Distributed trajectory design for data gathering using mobile sink in wireless sensor networks

Several studies have demonstrated the benefits of using a mobile sink (MS) to reduce energy consumption resulting from multi-hop data collection using a static sink in wireless sensor networks (WSNs). However, using MS may increase data delivery latency as it needs to visit each sensor node in the network to collect data. This is a critical issue in delay-sensitive applications where all sensed data must be gathered within a given time constraint. In this paper, we propose a distributed data gathering protocol utilizing MS for WSNs. The proposed protocol designs a trajectory for the MS, which minimizes energy consumption and delay. Our protocol operates in four main phases: data sensing, rendezvous point (RP) selection, trajectory design, and data gathering. In data sensing, a number of deployed sensor nodes keep sensing the target field for a specific period of time to capture events. Then, using a cluster-based RP selection algorithm, some sensor nodes are selected to become RPs based on local information. The selected RPs are then used to determine a trajectory for the MS. To do so, we propose three trajectory design algorithms that support different types of applications, namely reduced energy path (REP), reduced delay path (RDP), and delay bound path (DBP). The MS moves through the constructed path to accomplish its data gathering according to an effective scheduling technique that is introduced in this work. We validate the proposed protocol via extensive simulations over several metrics such as energy, delay, and time complexity.     

网络入侵检测技术研究

对入侵检测作较全面的综述性介绍，首先从入侵、入侵检测的概念出发，接着介绍入侵检测的分类和入侵检测系统的模型，最入对入侵检测的各种方法进行简要分析。     

基于ERPMT改进启发式方法的WSN寿命最大化算法

针对传感器节点的电池容量限制导致无线传感网络寿命低的问题,基于容量最大化(CMAX)、线上最大化寿命(OML)两种启发式方法以及高效路由能量管理技术(ERPMT),提出了基于ERPMT改进启发式方法的无线传感网络寿命最大化算法。首先,通过启发式方法初始化每个传感器节点,将节点能量划分为传感器节点起源数据和其它节点数据延迟;然后利用加入的一种优先度量延迟一跳节点的能量消耗;最后,根据路径平均能量为每个路由分配一个优先级,并通过ERPMT实现最终的无线传感网络优化。针对不同分布类型网络寿命的实验验证了本文算法的有效性及可靠性,实验结果表明,相比较为先进的启发式方法CMAX及OML,本文算法明显增大了无线传感网络的覆盖范围,并且大大地延长了网络的寿命。     

一种基于遗传算法的肽/蛋白质结合模式虚拟筛选建模技术

“合理”QSAR模型是指在了解配体与受体相互作用模式的前提下建立定量构效关系, 这样避开了传统做法仅仅依靠样本集分子自身信息来构建预测模型的诸多弊端. 本文将此思想应用于肽/蛋白质亲和活性的研究当中, 借助于遗传算法作为虚拟受体结合靶点及相互作用模式的筛选手段得到了一种新的建模技术: 肽/蛋白质结合模式遗传虚拟筛选(genetic virtual screening of combinative mode for peptide/protein, GVSC). 该法成功解决了“合理”QSAR研究中的难题, 即大多数情况下受体结构未知而难以了解配基与之发生的结合方式. 分别使用58个血管紧张素转化酶, 18个Camel抗体蛋白cAb-lys3双位点突变残基对GVSC加以检验, 其结果表明GVSC能够较好地阐明配基与受体之间的作用机理, 并能得到优于传统方法的QSAR模型.     

Recent Advancements on Immunomodulatory Mechanisms of Resveratrol in Tumor Microenvironment

Immunomodulation of the tumor microenvironment is emerging as an important area of research for the treatment of cancer patients. Several synthetic and natural agents are being investigated for their ability to enhance the immunogenic responses of immune cells present in the tumor microenvironment to impede tumor cell growth and dissemination. Among them, resveratrol, a stilbenoid found in red grapes and many other natural sources, has been studied extensively. Importantly, resveratrol has been shown to possess activity against various human diseases, including cancer. Mechanistically, resveratrol has been shown to regulate an array of signaling pathways and processes involving oxidative stress, inflammation, apoptosis, and several anticancer effects. Furthermore, recent research suggests that resveratrol can regulate various cellular signaling events including immune cell regulation, cytokines/chemokines secretion, and the expression of several other immune-related genes. In this review, we have summarized recent findings on resveratrol’s effects on immune regulatory cells and associated signaling in various cancer types. Numerous immunomodulatory effects of resveratrol suggest it may be useful in combination with other cancer therapies including immunotherapy for effective cancer management.     

CONVERGENCE OF CASCADE ALGORITHMS AND SMOOTHNESS OF REFINABLE DISTRIBUTIONS

In this paper, the author at first develops a method to study convergence of the cascade algorithm in a Banach space without stable assumption on the initial (see Theorem 2.1), and then applies the previous result on the convergence to characterizing compactly supported refinable distributions in fractional Sobolev spaces and Holder continuous spaces (see Theorems 3.1, 3.3, and 3.4). Finally the author applies the above characterization to choosing appropriate initial to guarantee the convergence of the cascade algorithm (see Theorem 4.2).     

双色激光场中1维共线氢分子离子的经典动力学研究

 运用经典理论方法,并采用辛算法数值求解了双色激光场作用下1维共线氢分子离子(H₂⁺)的哈密顿正则方程,得到了氢分子离子在激光场下的经典轨迹。计算了单色场和双色场下氢分子离子(H₂⁺)的存活几率、电离几率、解离几率、库仑爆炸几率随时间的演化,分析了双色场的相位、强度、强度比及倍频的变化对氢分子离子动力学行为的影响,并给出了相应的物理解释。