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101.
Omp33-36 in A. baumannii, a bacterium causing serious nosocomial infections, is a virulence factor associated with the pathogen metabolic fitness as well as its adherence and invasion to human epithelial cells. This protein is also involved in interaction of the bacteria with host cells by binding to fibronectin. Moreover, Omp33-36 renders cytotoxicity to A. baumannii in addition to inducing apoptosis and modulation of autophagy. In the present study, an integrated strategy is launched to pierce into the 3D structure of Omp33-36 protein. The signal peptide within the sequence was determined, then, topology as well as secondary and tertiary structures of the protein were predicted. The mature protein assigned as a 14-stranded barrel in which residues 1–19 is removed as signal peptide. The obtained 3D models were evaluated in terms of quality; and then, served as queries to find similar protein structures. The hits were analyzed regarding topology among which 14-stranded were considered. The most qualified model was refined and then its sequence aligned to its counterpart similar structure protein (CymA from Klebsiella oxytoca). The determined structure of Omp33-36 could justify its porin function and carbapenem-resistance associated with the loss of this protein. 相似文献
102.
The link quality was vulnerable to the complexity environment in wireless sensor network.Obtaining link quality information in advance could reduce energy consumption of nodes.After analyzing the existing link quality prediction methods,AdaBoost-based link quality prediction mechanism was put forward.Link quality samples in deferent scenarios were collected.Density-based unsupervised clustering algorithm was employed to classify training samples into deferent link quality levels.The AdaBoost with SVM-based component classifiers was adopted to build link quality prediction mechanism.Experimental results show that the proposed mechanism has better prediction precision. 相似文献
103.
The multi-attribute grey target decision method for attribute value within three-parameter interval grey number 总被引:1,自引:0,他引:1
Based on the grey system theory and methods, the grey-target decision-making problem is discussed, in which the attribute values are grey numbers and the maximum probability of the value of grey number is known. Firstly, the optimal effect vector is the positive bull’s-eye and positive bull’s-eye distance of each scheme is defined. Subjectively or objectively weighting method is integrated to determine the index weight and integrated optimization model of index weight is established. Finally, the critical effect vector is the negative bull’s-eye and negative bull’s-eye distance of each scheme is defined, then relative bull’s-eye distance and comprehensive the bull’s-eye distance of grey target decision-making are given. An example is also presented to illustrate the usefulness and effectiveness of the methods obtained in this paper and provides a new idea for grey target decision-making method research. 相似文献
104.
In social network services, such as Facebook, Google+, Twitter, and certain postings attract more people than others. In this paper, we propose a novel method for predicting the lifespan and retweet times of tweets, the latter being a proxy for measuring the popularity of a tweet. We extract information from retweet graphs, such as posting times; and social, local, and content features, so as to construct prediction knowledge bases. Tweets with a similar topic, retweet pattern, and properties are sequentially extracted from the knowledge base and then used to make a prediction. To evaluate the performance of our model, we collected tweets on Twitter from June 2012 to October 2012. We compared our model with conventional models according to the prediction goal. For the lifespan prediction of a tweet, our model can reduce the time tolerance of a tweet lifespan by about four hours, compared with conventional models. In terms of prediction of the retweet times, our model achieved a significantly outstanding precision of about 50%, which is much higher than two of the conventional models showing a precision of around 30% and 20%, respectively. 相似文献
105.
The measures and calculation of different properties such as refractive index, density, speed of sound, excess molar volume, and isentropic compressibility of the ternary heterogeneous compounds by ethanol + water + (n-hexane, n-heptane, n-octane, n-nonane) have been performed in the range 288.15–323.15 K and atmospheric pressure. Attending to the accurate results of these models, the equation of state enclosing mixing rules is indicated as a simple estimation of the procedures of these properties for this kind of multicomponent systems. 相似文献
106.
An improved rate control algorithm, designed for scalable video coders incorporating interlayer prediction, is proposed. Firstly, a Rate Distortion (RD) model for interlayer prediction involving the spatial enhancement layers is devised. An optimised Mean Absolute Difference (MAD) prediction model for the spatial enhancement layers that considers both the MAD from the spatial base layer in the same frame and the MAD from the corresponding macroblock in previous frames is also proposed. Simulation results show that the resulting algorithm produces accurate rate control with an average bit rate error of less than 0.26%. Compared with the JVT-W043 default rate control algorithm of the JSVM, the proposed algorithm improves the average PSNR by up to 0.53 dB or reduces the bit rate by an average of 10.95%. Furthermore, the proposed algorithm can be combined with the existing rate control scheme for H.264/AVC, resulting in further improvements. 相似文献
107.
Pierre Thureau Simone Sturniolo Miri Zilka Fabio Ziarelli Stéphane Viel Jonathan R. Yates Giulia Mollica 《Magnetic resonance in chemistry : MRC》2019,57(5):256-264
Structure determination of functional organic compounds remains a formidable challenge when the sample exists as a powder. Nuclear magnetic resonance crystallography approaches based on the comparison of experimental and Density Functional Theory (DFT)-computed 1H chemical shifts have already demonstrated great potential for structure determination of organic powders, but limitations still persist. In this study, we discuss the possibility of using 13C-13C dipolar couplings quantified on powdered theophylline at natural isotopic abundance with the help of dynamic nuclear polarization, to realize a DFT-free, rapid screening of a pool of structures predicted by ab initio random structure search. We show that although 13C-13C dipolar couplings can identify structures possessing long range structural motifs and unit cell parameters close to those of the true structure, it must be complemented with other data to recover information about the presence and the chemical nature of the supramolecular interactions. 相似文献
108.
The problem of oversampling parameter estimation for noisy sinusoidal signals is addressed. We first extend the weighted least squares (WLS) approach to the complex sinusoids. Then the oversampling weighted least squares (OSWLS) estimator is proposed based on data decimation. Estimation performance of the OSWLS method is analyzed via theoretical and simulation studies. Results are also compared to those of the WLS and decimative unitary ESPRIT methods as well as Cramér-Rao lower bound. 相似文献
109.
SU CaiHong 《中国科学:物理学 力学 天文学(英文版)》2014,57(5):950-962
Up to now,the most widely used method for transition prediction is the one based on linear stability theory.When it is applied to three-dimensional boundary layers,one has to choose the direction,or path,along which the growth rate of the disturbance is to be integrated.The direction given by using saddle point method in the theory of complex variable function is seen as mathematically most reasonable.However,unlike the saddle point method applied to water waves,here its physical meaning is not so obvious,as the frequency and wave number may be complex.And on some occasions,in advancing the integration of the growth rate of the disturbance,up to a certain location,one may not be able to continue the integration,because the condition for specifying the direction set by the saddle point method can no longer be satisfied on the basis of continuously varying wave number.In this paper,these two problems are discussed,and suggestions for how to do transition prediction under the latter condition are provided. 相似文献
110.