动力调谐陀螺仪的瞬态动力学及误差分析

为了建立陀螺仪在过载—振动复合环境下的误差模型,应用有限元分析软件ANSYS,针对某型导弹使用的动力调谐陀螺仪的结构,建立基于具体参数的实体和有限元动力学模型,并开展了陀螺仪的瞬态动力学分析研究,由此计算由于陀螺转子和平衡环的质心偏移造成的陀螺仪漂移误差,得到在过载—振动复合环境下陀螺仪漂移角速度与在过载、振动单一环境下漂移角速度之间的关系。     

一种新的全姿态指示画面填充算法

现代飞机座舱主飞行仪显示系统中,全姿态指示天地区域的填充是件非常费时的工作。提出了一种新的区域填充算法。该算法第一步引入分块查找的思想以及基于填充区域的特点确定采用水平线或者竖直线扫描方式,并且对区域轮廓中满足关键码字段的像素点建立坐标数组;第二步根据已确定的扫描方式进行区域填充。此外,求取新旧地平线交点并没有采用通过大量数值计算直接求取的方法,而是采用了比较法。实验结果表明该算法显著提高了填充速度和显示效果,降低了数据存储空间量。     

The Pharmacokinetics in Mice and Cell Uptake of Thymus Immunosuppressive Pentapeptide Using LC-MS/MS Analysis

Thymus immunosuppressive pentapeptide (TIPP) is a novel anti-inflammatory peptide with high efficacy and low toxicity. This study aims to establish a selective LC-MS/MS method for analyzing the analyte TIPP in biological samples, laying the foundation for further PK and PD studies of TIPP. Protein precipitation was conducted in acetonitrile supplemented with 2% formic acid and 25 mg/mL dithiothreitol as a stabilizer, which was followed by backwashing the organic phase using dichloromethane. The chromatographic separation of TIPP was achieved on a C18 column with a gradient elution method. During positive electrospray ionization, TIPP was analyzed via multiple-reaction monitoring. The linear relationships between the concentration of TIPP and peak area in murine plasma cell lysates, supernatants, and the final cell rinse PBS were established within the ranges of 20–5000 ng/mL, 1–200 ng/mL, 10–200 μg/mL, and 0.1–20 ng/mL, respectively (r² > 0.99). Validated according to U.S. FDA guidelines, the proposed method was proved to be acceptable. Such a method had been successfully applied to investigate the pharmacokinetics of TIPP in mice via subcutaneous injection. The plasma half-life in mice was 5.987 ± 1.824 min, suggesting that TIPP is swiftly eliminated in vivo. The amount of TIPP uptake by RBL-2H3 cells was determined using this method, which was also visually verified by confocal. Furthermore, the effective intracellular concentration of TIPP was deduced by comparing the intracellular concentration of TIPP and degrees of inflammation, enlightening further investigation on the intracellular target and mechanism of TIPP.     

The DI-SPME Method for Determination of Selected Narcotics and Their Metabolites,and Application to Bone Marrow and Whole Blood Analysis

The present investigation utilised the quick and easy SPME/LC-MS method to determine selected narcotic substances and their metabolites in whole blood. The study included qualitative analysis and validation of the method. Analytes were determined in the linearity range of 25–300 ng/mL. The precision during and between days (in general CV < 13.41%), and the LOD which results in between 0.36 and 11.08 ng/mL, and the LOQ between 1.20 and 36.90 ng/mL were investigated. The validation results obtained, as well as the results of subsequent in-laboratory tests, confirmed the applicability of the method in the analysis of blood samples. An attempt to apply the method to the analysis of bone marrow samples has yielded promising results; however, more detailed studies are needed in this area.     

基于改进GMM与帧差法的运动棉杂率分析算法研究

针对清梳棉流程中产出棉含杂高、质量差的问题,结合改进高斯混合模型(Gaussian mixed model,GMM)与帧差法,提出一种局部运动棉杂率控制优化方法。首先针对清棉机除杂原理及棉杂特性进行分析;其次通过提取视频关键帧并改进GMM与帧差法对图像序列“与”运算实现目标的精确提取,进而通过设计GMM分类器获得棉杂率并进行分析;最后与传统的检测算法作对比验证。实验表明,改进后的算法在有效性以及实用性方面优于传统算法。同时,通过引入闭环控制能满足工业高精度、实时性的需求。     

氦原子及类氦离子基态的二参数变分法研究

提出了一种计算氦原子及类氦离子基态能量和波函数的二参数变分法,包括试探波函数的设计和基态能量表达式的推导,并用Mathematica 5.0软件的优化计算功能方便快捷地计算出基态能量,将计算结果与实验结果和部分所列文献的结果进行对比.结果表明,本文所得精度较高,变分参数个数较少.同时强调交换对称性和量子态的交缠在双电子原子体系问题中的重要性.     

Fe2O3气敏材料研究进展

综述了近年来Fe_2O_3气敏材料常用的合成方法,如sol-gel法,沉淀法,水热法和微乳液法。总结了焙烧温度与掺杂效应对气敏性能的影响,探讨了气敏机理模型,并对今后的研究方向提出了一些看法。     

电子束曝光机工作台吊装结构动态特性的研究

正在研制的激光定位吊装结构工作台系统是电子束曝光机的主要组成部分。本文概述了工作台吊装结构的特点,用有限元法建立了吊装结构的三维实体力学模型,在理论上对其进行了动态特性分析与计算,并用锤击法进行了测试。分析与实验表明,工作台吊装结构抗冲击能力很强,能够满足电子束曝光机高精度和高速度的要求。     

一种具有自动纠错功能的FIR滤波器研究

提出了一种有效实现自动纠错功能FIR数字滤波器技术,该技术采用2种不同架构的标准滤波器通过并行操作来完成。任一滤波器软错误的发生就会引起两个滤波器输出不匹配,达到检测错误的目的,增强了传统滤波器对差错检测和差错纠正的支持。最后对该滤波器地性能进行评估,该滤波器性能良好,纠错率接近100%,可广泛运用在各种信号处理中。     

[110]/(001)单轴应力对硅价带结构及空穴有效质量的影响

采用K.P微扰法研究了当硅在[110]/(001)方向受一单轴应力作用时, 应力对硅价带结构及有效质量的影响。结果表明：硅在压应力作用下的价带分裂能要大于同样大小的张应力作用下的价带分裂能;在常见的几种晶向中,有效质量沿[110]晶向是最小的。从抑制带间散射,减小有效质量增强迁移率的角度考虑,沿应力方向的[110]晶向最适宜作为载流子的输运方向。所获得的结论可为单轴应变硅器件应力及导电沟道方向的选择设计提供理论参考。