Metabolic characterization of the early stage of hepatic fibrosis in rat using GC‐TOF/MS and multivariate data analyses

The aim of this study was to explore the changes in the urine metabolic spectrum in rats with the early stage of liver fibrosis using gas chromatography–time of flight/mass spectrometry (GC‐TOF/MS), try to search for potential biomarkers and elucidate the probably metabonomic pathogenesis. The early stage of liver fibrosis was established with a single subcutaneous injection of carbon tetrachloride twice each week for 4 weeks continuously. At the end of the experiment, GC‐TOF/MS technology with multivariate statistical approaches such as principal component analysis, partial least squares‐discriminant analysis and orthogonal partial least squares‐discriminant analysis was used to analyze the changes in the metabolic spectrum trajectory and identify potential biomarkers. Twelve potential biomarkers in the model group, such as succinic acid, threonine and lactose, were selected, which indicate that the metabonomic pathogenesis of the early stage of liver fibrosis may be related to disorders of energy metabolism, amino acid metabolism and fatty acid metabolism.     

雷达网反隐身优化部署决策模型及算法研究

隐身目标的RCS在空域、频域及极化域等方面均呈现出不一致特性。利用隐身目标的低隐身效果的“空域窗口”优化多部雷达布站，是一项具有现实意义的课题。基于对隐身飞机RCS与雷达波入射角关系的具体分析，提出了雷达网消盲指数的概念和定量表达式，建立了一种小型雷达群的空域反隐身优化部署决策模型，并对具体的优化部署算法进行了研究。利用典型雷达装备进行的仿真试验验证了其有效性。     

宽带混沌信号在汽车防撞雷达中的应用

随着汽车用量的增长，汽车防撞雷达对提高交通安全性有着极其晕要的现实意义，而传统的线性调频连续波雷达体制中存在着严重的多用户同频电磁干扰问题。由于宽带混沌信号具有良好的相关特性，文中提出了数字处理方式的宽带混沌调频连续波雷达，采用混沌调频信号来代替传统的线性调频信号的方案，结果显示它很好地解决丁加性高斯白噪声干扰和多用户间的交叉干扰问题；系统利用了离散混沌序列驱动连续混沌系统产生宽带混沌信号的方法，其电路结构简单，所得频谱平坦宽阔，在汽车防撞雷达和其他雷达、通信系统中具有很好的应用前景。     

红外警戒系统目标识别方法的研究

讨论了红外警戒系统目标识别的方法。由于目标和背景杂波在特征上既有区别又有相似之处，采用单一的识别手段无法达到满意的性能，只有在空间、时间和光谱域内采用多种手段，才能逐渐排除杂波，获取真正的威胁目标。     

Isotropic Evolution of a JBD Anisotropic Bianchi Universe

I study the dynamical effects due to the Brans-Dicke scalar -field at the early stages of a supposedly anisotropic Universe expansion in the scalar-tensor cosmology of Jordan-Brans-Dicke. This is done considering the behaviour of the general solutions for the homogeneous model of Bianchi type VII in the vacuum case. I conclude that the Bianchi-VII₀ model shows an isotropic expansion and that its only physical solution is equivalent to a Friedman-Robertson-Walker spacetime whose evolution can, depending on the value of the JBD coupling constant, begin in a singularity and, after expanding (inflating, if > 0), shrink to another, or starting in a non-singular state, collapse to a singularity. I also conclude that the general Bianchi-VII _h (with h 0) models show strong curvature singularities producing a complete collapse of the homogeneity surfaces to 2D-manifolds, to 1D-manifolds or to single points. Our analysis depends crucially on the introduction of the so-called intrinsic time, , as the product of the JBD scalar field times a mean scale factor a ³ = a ₁ a ₂ a ₃, in which the finite-cosmological-time evolution of this universe unfolds into an infinite -range. These universes isotropize from an anisotropic initial state, thence I conclude that they are stable against anisotropic perturbations.     

An Approach to Early Prediction of Software Quality

Due to the rapid development of computers and their applications,early software quality prediction in software industry becomes more and more crucial. Software quality prediction model is very helpful for decision-makings such as the allocation of resource in module verification and validation. Nevertheless,due to the complicated situations of software development process in the early stage,the applicability and accuracy of these models are still under research. In this paper,a software quality prediction model based on a fuzzy neural network is presented,which takes into account both the internal factors and external factors of software. With hybrid-learning algorithm,the proposed model can deal with multiple forms of data as well as incomplete information,which helps identify design errors early and avoid expensive rework.     

预警的概念及相关物理问题

预警是现代社会减轻自然灾害的工作中最重要的物理概念之一,也是在预测/预报的物理问题没有得到解决的情况下最具实际意义的技术之一.文章介绍了与预警有关的概念和物理问题,包括预报和预警的概念,现地预警和异地预警,讨论了不同领域的预警技术中共同的物理问题,包括“有限传播”原理、“连锁效应”原理、“相似放大”原理,以及实际工作对预警系统的主要技术要求.     

光纤延迟线长度编码优化设计

在光纤延迟测向激光告警系统中，光纤延迟线是用来连接光学接收系统和光电转换系统的．起到传输光、延迟光、对光信号进行编码的作用。由于光纤延迟线的长度不同，光学窗口接收到的激光脉冲产生不同的时间延迟．从而实现激光方位信息到时间信息的转变。光纤延迟线的长度对激光告警器的体积、光学损耗、虚警率等因素有着直接的影响，在此利用激光脉冲的相关特性，通过最优化理论对光纤延迟线进行排列组合．提出了光纤延迟线长度编码的优化设计方法，通过对相关理论的分析与计算．得到了一个全向矩阵的排列方式，从而得出了相应的排列原则。按照该原则对光纤延迟线进行排列组合，从理论上得到了最优的光纤延迟线总长度值，为激光测向告警器的优化设计提供了重要的理论依据。     

"解剖"激光告警

介绍了激光告警的作用,分析了激光告警器的原理、性能要求和分类,然后分别阐述了典型的光谱识别型、相干识别型和散射探测型激光告警器,并对不同类型的激光告警器进行了比较评价.     

医院感染实时监测和预警系统在临床护理中的应用效果调查

目的 :对医院感染实时监测和预警系统在临床中的应用效果进行分析和研究。方法 :所选用B/S构架及J2EE的新开发技术,后台的数据库系统是以SQL SERVER为主,后台的数据库系统是可以与目前各个医院信息系统相连接的,是医院感染管理信息系统得到有力的开发。结果 :对医院感染所发生的发病情况和因素进行实时监测和预警系统,可以起到有效安全的检测和统计功能。结论 :通过对医院感染进行实时的检测和预警系统在临床中的实践应用效果,使医院感染检测的安全性和准确性得到充分的提高,同时也大大提高了医院感染管理的质量和效果。