衰减振荡电流下火花电阻的光谱诊断

气体开关是脉冲功率系统的关键部件,开关的火花通道阻抗直接影响负载电压的陡度及其能量传输效率。提出一种光谱学诊断方法,通过对火花通道成像光谱的时空分辨测量,获得通道半径及电导率,从而计算时变的火花电阻。光谱测量结果表明,氮气间隙火花放电通道电子温度为2~3eV,通道电导率先增大后减小,最大值约16 000S,随着放电发展,火花通道电阻从绝缘状态快速跌落并趋于稳定值,时变趋势与电学计算结果基本吻合。3~100kPa范围内,随着气压增大,放电通道半径减小,火花通道电阻增大。     

Competitive hydrogen bonding of cyclopropenium ions: Implications of an anion switch

This work demonstrates how modulating hydrogen bonding between intermolecular, bifurcated, and intramolecular interactions can be used to tune the structural, electronic, and photophysical properties of cyclopropenium ions and their respective fluorophores. The basis of this switchability was examined using X-ray diffraction analysis, ¹H NMR spectroscopy, DFT calculations, and fluorescence spectroscopy.     

Luminescence Switching of Organogold(I) Complexes between Aggregation-induced Phosphorescence Enhancement and Aggregation-caused Quenching by Balancing Auxiliary Ligands around the AuI Center

Attaching AIE-active L1 ([1,1′:2′,1′′:4′′,1′′′-quaterphenyl]-2-yldiphenylphosphane) to AuCl, shortened the distances of P−C bonds to promote electron cloud overlap between Au^I and L1 , affords 1 ( L1 AuCl) with aggregation-induced phosphorescence enhancement (AIPE) activity by ³LMCT transitions. Then substituting the coplanar L2 (9-ethynylanthracene) for the Cl⁻ in 1 providing 2 , switches the luminescence to aggregation-caused quenching (ACQ) activity. Furthermore, we restore the performance from ACQ to AIPE by metathesis reactions to transfer 2 into 1 . It is versatile synthetic strategy of reversible transformation between 1 and 2 that switches the luminescence of organogold(I) between AIPE and ACQ through balancing auxiliary ligands around the given metal.     

Switching the Switch: Ligand Induced Disulfide Formation in HDAC8

Human histone deacetylase 8 is a well-recognized target for T-cell lymphoma and particularly childhood neuroblastoma. PD-404,182 was shown to be a selective covalent inhibitor of HDAC8 that forms mixed disulfides with several cysteine residues and is also able to transform thiol groups to thiocyanates. Moreover, HDAC8 was shown to be regulated by a redox switch based on the reversible formation of a disulfide bond between cysteines Cys₁₀₂ and Cys₁₅₃. This study on the distinct effects of PD-404,182 on HDAC8 reveals that this compound induces the dose-dependent formation of intramolecular disulfide bridges. Therefore, the inhibition mechanism of HDAC8 by PD-404,182 involves both, covalent modification of thiols as well as ligand mediated disulfide formation. Moreover, this study provides a deep molecular insight into the regulation mechanism of HDAC8 involving several cysteines with graduated capability to form reversible disulfide bridges.     

GW35型隔离开关操作过程中触头烧毁问题分析

随着电力企业的快速发展,隔离开关被广泛使用.现在,电力系统中的GW35型隔离开关在运行过程中不仅受外界环境的影响还受自身结构的影响使得GW35型隔离开关在使用操作过程常出现触头烧毁问题,影响着供电系统的安全稳定性.     

FHIT-Substrate Complexes: a New Paradigm in Reversible Protein Phosphorylation

Fhit is a tumor suppressor protein encoded at the most fragile site in the human genome that is inactivated by genetic deletions early in the development of many cancers. A member of the Histidine Triad (HIT) superfamily of nucleotide-binding proteins, Fhit binds diadenosine triphosphate (ApppA) and cleaves it to produce AMP + ADP. The His96Asn mutation of Fhit, which reduces k_cat by more than a million-fold, does not reduce tumor suppressor activity in a nude mouse assay. Thus, genetic and biochemical evidence suggest that ApppA binding but not cleavage is required for tumor suppression. Crystal structures of Fhit bound to a nonhydrolyzable ApppA analog revealed that Fhit binds two substrates per dimer, presenting all of the phosphates and two of the adenosines on the surface of the protein in place of a deep, positively charged groove in the empty Fhit protein dimer. It is proposed that signaling by Fhit is mediated by presentation of nucleotide substrates to cytosolic effectors.     

DYL高速视频12位DAC的研制

文中介绍了以我国独创的DYL多元逻辑电路为基础,并配合了申请国家发明专利的高速差动电压模拟开关构成的12位高速DAC转换器。同时解决了以往高速转换器输出阻抗、使用范围受限的缺点。同时对所研制的高速DAC在结构、工艺、修正技术及测试上进行了多方面的研究探讨。     

Delayed stability switches in singularly perturbed predator–prey models

In this paper we provide an elementary proof of the existence of canard solutions for a class of singularly perturbed planar systems in which there occurs a transcritical bifurcation of the quasi steady states. The proof uses the one-dimensional result proved by V.F. Butuzov, N.N. Nefedov and K.R. Schneider, and an appropriate monotonicity assumption on the vector field. The result is applied to identify all possible predator–prey models with quadratic vector fields allowing for the existence of canard solutions.     

应用于大功率MMIC开关的AlGaN背势垒GaN HEMT

报道了应用于大功率开关的AlGaN背势垒0.25μm GaN HEMT。通过引入AlGaN背势垒,MOCVD淀积在3英寸SiC衬底上的AlGaN/GaN异质结材料缓冲层的击穿电压获得了大幅度的提升,相比于普通GaN缓冲层和掺Fe GaN缓冲层击穿电压提升幅度分别为4倍和2倍。采用具有AlGaN背势垒AlGaN/GaN 外延材料研制的GaN HEMT开关管在源漏间距为2μm、2.5μm、3μm、3.5μm和4μm时,估算得到的关态功率承受能力分别为25.0W、46.2W、64.0W、79.2W和88.4W。基于源漏间距为2.5μm的GaN HEMT开关管设计了DC-12GHz的单刀双掷MMIC开关。该开关采用了反射式串-并-并结构,整个带内插入损耗最大1.0dB、隔离度最小30dB,10GHz下连续波测试得到其功率承受能力达44.1dBm。     

高端路由器主备同步技术的研究

高端路由器设备通常采用主备倒换来延长系统的可靠运行时间,而主备数据同步是实现主备倒换的关键技术。针对传统主备同步技术可靠性低,同步速率低的问题,提出了一种新的主备数据同步解决方案。新的主备同步方案使用了可靠的主备数据同步通道;提出给同步数据分类,并采用合适的方法同步。经实验验证,该技术方案应用在高端路由器上,提高了主备同步速率与可靠性,从而提高了系统性能,同时模块化的设计,具有很好的通用性,实现简单,实用性高。