光链路检测系统在网管中的设计与实现

主要利用网管设计实现对集成了光时域反射仪(OTDR)板卡的OLT设备进行管理,达到监控管理光链路状况的目的。该方案具有自动检测和手动检测的功能,图形化的界面能实时显示测试与诊断结果。检测过程更简单,采集手段更完善,测试结论更准确,具有很强的实时性和实用性。     

VSAT的技术进展

本文从传输技术、多址接入方式、网络管理和网络体系结构等方面综述了甚小口径卫星地球站在技术上的最新进展。     

通信网的信息安全

本文首先介绍了通信网安全的基本含义，进而提出了信息安全的层次结构，用户信息安全和网络信息安全的主要内容以及实现信息安全的服务和机制。     

一种自组织结构的神经网络模式分类器

本文研究了一种自组织结构的神经网络模式分类器．它由一个多层网络和一个自组织机构组成．通过对训练样本的聚类分析，它能有效地构造和训练网络，并能在学习过程中自适应地调节网络结构．它具有收敛速度快，能避免局部极值点和应用方便等显著优点．计算机模拟实验证实了其优越性．     

全光通信网安全问题初探

本文介绍了全光通信网(AON)的概念。研究了全光网络中光层可能遭到的两种网络攻击:服务玻坏和网络窃听以及对网络通信安全的影响。提出了全光网络安全的考虑方法和可以采取的安全策略。     

广电网络业务发展的分析

以促进广电网络发展为纲,分析广电主要的3项增值业务:付费频道,高清互动,宽带业务。从实际出发,分析现状并为其正确定位,对其发展方向及业务增长方式题出建议,指出广电未来以电视业务宽带业务为主线的盈利格局。     

中兴通讯IP over WDM解决方案

介绍了IP网络的发展趋势,承载电信级业务的IP承载网的3种组网方式,着重介绍了IP over WDM解决方案的优势和特点。     

基于分解技术的动态结构神经网络

本文提出了基于分解技术的动态结构神经网络算法，这种算法能通过分析网络输入输出了空间的维数，确定每一隐含层神经元数目，为了加快学习效率，采用变误差混学习算法，仿真结果验证了这种算法的有效性。     

An Integrated Mass Spectrometry-Based Glycomics-Driven Glycoproteomics Analytical Platform to Functionally Characterize Glycosylation Inhibitors

Cancer progression is linked to aberrant protein glycosylation due to the overexpression of several glycosylation enzymes. These enzymes are underexploited as potential anticancer drug targets and the development of rapid-screening methods and identification of glycosylation inhibitors are highly sought. An integrated bioinformatics and mass spectrometry-based glycomics-driven glycoproteomics analysis pipeline was performed to identify an N-glycan inhibitor against lung cancer cells. Combined network pharmacology and in silico screening approaches were used to identify a potential inhibitor, pictilisib, against several glycosylation-related proteins, such as Alpha1-6FucT, GlcNAcT-V, and Alpha2,6-ST-I. A glycomics assay of lung cancer cells treated with pictilisib showed a significant reduction in the fucosylation and sialylation of N-glycans, with an increase in high mannose-type glycans. Proteomics analysis and in vitro assays also showed significant upregulation of the proteins involved in apoptosis and cell adhesion, and the downregulation of proteins involved in cell cycle regulation, mRNA processing, and protein translation. Site-specific glycoproteomics analysis further showed that glycoproteins with reduced fucosylation and sialylation were involved in apoptosis, cell adhesion, DNA damage repair, and chemical response processes. To determine how the alterations in N-glycosylation impact glycoprotein dynamics, modeling of changes in glycan interactions of the ITGA5–ITGB1 (Integrin alpha 5-Integrin beta-1) complex revealed specific glycosites at the interface of these proteins that, when highly fucosylated and sialylated, such as in untreated A549 cells, form greater hydrogen bonding interactions compared to the high mannose-types in pictilisib-treated A549 cells. This study highlights the use of mass spectrometry to identify a potential glycosylation inhibitor and assessment of its impact on cell surface glycoprotein abundance and protein–protein interaction.     

Prisoner’s Dilemma Game with Cooperation-Defection Dominance Strategies on Correlational Multilayer Networks

As multilayer networks are widely applied in modern society, numerous studies have shown the impact of a multilayer network structure and the network nature on the proportion of cooperators in the network. In this paper, we use Barabási–Albert scale-free networks (BA) and Watts and Strogatz networks (WS) to build a multilayer network structure, and we propose a new strategy-updating rule called “cooperation-defection dominance”, which can be likened to dominant and recessive traits in biogenetics. With the newly constructed multilayer network structure and the strategy-updating rules, based on the simulation results, we find that in the BA-BA network, the cooperation dominance strategy can make the networks with different rs show a cooperative trend, while the defection dominance strategy only has an obvious effect on the network cooperation with a larger r. When the BA network is connected to the WS network, we find that the effect of strategy on the proportion of cooperators in the network decreases, and the main influencing factor is the structure of the network. In the three-layer network, the cooperation dominance strategy has a greater impact on the BA network, and the proportion of the cooperators is enhanced more than under the natural evolution strategy, but the promotion effect is still smaller than that of the two-layer BA network because of the WS network. Under the defection dominance strategy, the WS layer appears different from the first two strategies, and we conclude through simulation that when the payoff parameter is at the middle level, its cooperator proportion will be suppressed, and we deduce that the proportion of cooperators and defectors, as well as the payoff, play an important role.