通信局房工艺要求设计要点

本文结合未来发展方向和工程设计实例,从局址选择、层高分析、光电缆进局、电缆上线井几个方面对通信机房工艺对土建要求的重点问题进行总结归纳。     

A virtual high throughput screen for high affinity cytochrome P450cam substrates. Implications for in silico prediction of drug metabolism

Structure-based virtual screening techniques require reliable scoring functions to discriminate potential substrates effectively. In this study we compared the performance of GOLD, PMF, DOCK and FlexX scoring functions in FlexX flexible docking to cytochrome P450cam binding site. Crystal structures of protein-substrate complexes were most effectively reproduced by the FlexX/PMF method. On the other hand, the FlexX/GOLD approach provided the best correlation between experimental binding constants and predicted scores. Binding modes selected by the FlexX/PMF approach were rescored by GOLD to obtain a reliable measure of binding energetics. The effectiveness of the FlexX/PMF/GOLD method was demonstrated by the correct classification of 32 out of the 33 experimentally studied compounds and also in a virtual HTS test on a library of 10,000 compounds. Although almost all the available functions were developed to be general, our study on cytochrome P450cam substrates suggests that careful selection or even tailoring the scoring function might increase the prediction power of virtual screens significantly. The FlexX/PMF/GOLD methodology was tested on cytochrome P450 3A4 substrates and inhibitors. This preliminary study revealed that the combined function was able to recognise 334 out of the 345 compounds bound to 3A4.     

泛亚C14发动机配气机构单阀系动力学分析

利用TYCON软件分别分析评价了C14配气机构中凸轮与平面挺柱之间的动力学关系、气阀落座情况、气阀弹簧各有效圈动力特性等。     

具有非轴对称刚度转轴的分岔

研究具有非轴对称刚度转轴的１／２亚谐共振和分岔,首先用Ｈａｍｉｌｔｏｎ原理导出运动微分方程,这是刚度系数周期性变化的参数激励方程,然后用多尺度法求得平均方程分岔响应方程和定常解,最后用奇异性理论分析分岔响应方程和定常解的稳定性,得到了局部分岔集和不同区域的不同分岔响应曲线。     

大位移Timoshenko转轴三维耦合动力学分析

对于高速柔性转轴,综合考虑滑移、弯曲、剪切变形、旋转惯性、陀螺效应和动不平衡等因素,运用Timoshenko旋转梁理论,给出弹性体空间运动的一般性描述,通过Hamilton原理建立弯曲-扭转-轴向三维耦合非线性动力学方程,应用参数摄动方法和假设振型方法进行化简,并用数值模拟分析了轴向刚性滑移、剪切变形、截面尺寸和转速等因素对转轴动力学响应的影响。     

HOMOGENIZATION—BASED TOPOLOGY DESIGN FOR PURE TORSION OF COMPOSITE SHAFTS

In conjunction with the homogenization theory and the finite element method, the mathematical models for designing the corss-section of composite shafts by maximizing the torsion rigidity are developed in this paper. To obtain the extremal torsion rigidity, both the cross-section of the macro scale shaft and the representative microstructure of the composite material are optimized using the new models. The micro scale computational model addresses the problem of finding the periodic microstructures with extreme shear moduli. The optimal microstructure obtained with the new model and the homogenization method can be used to improve and optimize natural or artificial materials. In order to be more practical for engineering applications, cellular materials rather than ranked materials are used in the optimal process in the existence of optimal bounds for the elastic properties. Moreover, the macro scale model is proposed to optimize the cross-section of the torsional shaft based on the tailared composites. The validating optimal results show that the models are very effective in obtaining composites with extreme elastic properties, and the cross-section of the composite shaft with the extremal torsion rigidity. The project supported by the National Natural Science Foundation of China (10172078 and 10102018)     

小型连续变焦相机的结构实现

介绍了一种小型大变倍比变焦相机的主要技术参数,以及采用的变焦方法;详细描述了相机的组成结构,其中变倍和补偿透镜组通过滑架在主体内滑动,其运动轨迹取决于导钉在凸轮曲线槽内的运动状态;阐述了加工和装调过程中为保证相机设计质量而采取的精度保证措施,凸轮曲线槽与滚子的配合间隙应控制在6~9 μm,确保主体的刚度和圆柱度,变倍和补偿滑架在主体内滑动时的返回空回误差<2″,滑架直径D与滑架长度L之间的比值≥1。经高低温和振动试验后检测结果表明：在50 lp/mm空间频率下,相机光学传递函数>0.2,相机外景成像清晰,层次分明。     

在伽利略坐标变换下的二端面弹性转轴相似动力学方程

在非相对论性原理下建立了二端面弹性转轴的相似动力学方程.使弹性转轴的动力学方程与地面坐标下的动力学方程相似,为相似工程学和计量、测控仪器的相似标定提供理论依据及方法 关键词： 二端面弹性转轴 相似模拟 坐标变换 相似动力学方程 标定     

基于DEMON线谱的轴频提取方法研究

目标的螺旋桨不同则轴频不相同。轴频是目标的特征之一,可以应用于目标识别当中。本文提出一种改进的高频噪声解调分析(DEMON)方法,能够得到具有明显线谱的DEMON谱;提出最大公约数算法,并给出提取轴频的具体步骤。海试数据实验结果验证了本文所提方法及算法的有效性和可行性。     

透雾连续变焦镜头的小型化设计

根据探测设备电视通道要求实现普通彩色和透雾黑白两种模式观察并小型化的特点,运用最速变焦路线凸轮曲线的设计及凸轮曲线平滑性优化的方法实现了小型化设计;采用可见光加近红外波段并在全波段范围内进行像质评价的方法,即根据外形尺寸计算中所求出的每个透镜组的光焦度和通光口径,参考现有结构,选定每组透镜的结构形式,缩放成要求的焦距以后组合成全系统进行像差校正,这样既可实现普通彩色和透雾黑白两种模式的观察,又保证了系统的齐焦性.系统通过了像质检测、实景成像的验证及环境应力筛选及环境例行试验的考查,并成功地用于探测设备.