Galactose-Grafted 2D Nanosheets from the Self-Assembly of Amphiphilic Janus Dendrimers for the Capture and Agglutination of Escherichia coli

High aspect ratio, sugar-decorated 2D nanosheets are ideal candidates for the capture and agglutination of bacteria. Herein, the design and synthesis of two carbohydrate-based Janus amphiphiles that spontaneously self-assemble into high aspect ratio 2D sheets are reported. The unique structural features of the sheets include the extremely high aspect ratio and dense display of galactose on the surface. These structural characteristics allow the sheet to act as a supramolecular 2D platform for the capture and agglutination of E. coli through specific multivalent noncovalent interactions, which significantly reduces the mobility of the bacteria and leads to the inhibition of their proliferation. Our results suggest that the design strategy demonstrated here can be applied as a general approach for the crafting of biomolecule-decorated 2D nanosheets, which can perform as 2D platforms for their interaction with specific targets.     

An Ultra-Microporous Metal–Organic Framework with Exceptional Xe Capacity

Molecular confinement plays a significant effect on trapped gas and solvent molecules. A fundamental understanding of gas adsorption within the porous confinement provides information necessary to design a material with improved selectivity. In this regard, metal–organic framework (MOF) adsorbents are ideal candidate materials to study confinement effects for weakly interacting gas molecules, such as noble gases. Among the noble gases, xenon (Xe) has practical applications in the medical, automotive and aerospace industries. In this Communication, we report an ultra-microporous nickel-isonicotinate MOF with exceptional Xe uptake and selectivity compared to all benchmark MOF and porous organic cage materials. The selectivity arises because of the near perfect fit of the atomic Xe inside the porous confinement. Notably, at low partial pressure, the Ni–MOF interacts very strongly with Xe compared to the closely related Krypton gas (Kr) and more polarizable CO₂. Further ¹²⁹Xe NMR suggests a broad isotropic chemical shift due to the reduced motion as a result of confinement.     

路由器端电子邮件拦截与放行设计与实现

针对实时电子邮件传输过程中安全性和可靠性的需求,提出一种在路由器端基于特征分析的拦截与放行方法。通过对电子邮件传输协议和内核机制的分析,以及对特征文件的解析,在内核态下采用多模式匹配方法对数据包进行识别及时的做出判断。实验结果表明,在满足可行性的前提下,对邮件实现安全性过滤,该方法具有很好的时效性。     

Synthesis and cytotoxicity of novel cholesterol–cobalt bis(dicarbollide) conjugates

The novel conjugates of cholesterol with cobalt – bis(dicarbollide) were synthesized by the ring-opening reactions of the cyclic oxonium derivatives of [3,3′-Co(C₂B₉H₁₁)₂]^– with the OH group of cholesterol 2-hydroxyethyl ether. The compounds obtained were tested for toxicity to glioblastoma U-87 MG cells and human embryo fibroblasts FECH-15 cells     

Transition metal mediated functionalization of o-carboranes

<正>Carboranes are a class of boron hydride clusters in which one or more of the BH vertices are replaced by CH units.Unlike small boranes, carboranes are kinetically and thermodynamically very stable as well as relatively chemically inert, which are often called three-dimensional relatives of benzenes. They are finding many applications in medicine as boron neutron capture therapy(BNCT) agents, in nanomaterials/supramolecular design as building blocks, and as ligands for transition metals [1]. However, their unique structures make derivatization difficult, which limits their application scope. To this end, there is a need to develop     

Salient video cube guided nighttime vehicle braking event detection

In nighttime driving brake lights are particularly important because they offer a warning signal to prevent potential collisions. In this work, we propose a novel visual-based approach for nighttime brake light detection using three-dimensional Nakagami imaging to analyze tail lights of vehicles in front. Rather than heuristic features, such as symmetry of taillights and appearance of the third brake light, the proposed approach extracts invariant features by modeling the scattering of brake lights, thus allowing detection to proceed in a part-based manner. Experiments from extensive datasets show that the proposed system can effectively detect vehicle braking under different lighting and traffic conditions, making it a realistic option for real-world applications.