基于G/S模式的空间信息云服务架构研究

针对多系统间的数据交换、共享问题,尤其在大数据时代,海量的数据增长给数据的管理带来的挑战,提出了一种基于G/S(General-Browser/ Service-Cloud,G/S)模式的空间信息云服务架构——面向数据的架构(Data Oriented Architecture,DOA)。以数据为核心,以数据标识为主线,通过数据注册中心和数据交换规范XXML(Specific Industry Markup Language),对海量异构数据进行存储、计算和管理,实现多系统间的数据共享、访问和协同。通过在地质灾害监测预警方面的应用,证明了该架构作为信息技术的系统构建方法在大数据时代独特的优势。     

A network-based pharmacology study of active compounds and targets of Fritillaria thunbergii against influenza

Seasonal and pandemic influenza infections are serious threats to public health and the global economy. Since antigenic drift reduces the effectiveness of conventional therapies against the virus, herbal medicine has been proposed as an alternative. Fritillaria thunbergii (FT) have been traditionally used to treat airway inflammatory diseases such as coughs, bronchitis, pneumonia, and fever-based illnesses. Herein, we used a network pharmacology-based strategy to predict potential compounds from Fritillaria thunbergii (FT), target genes, and cellular pathways to better combat influenza and influenza-associated diseases. We identified five compounds, and 47 target genes using a compound-target network (C-T). Two compounds (beta-sitosterol and pelargonidin) and nine target genes (BCL2, CASP3, HSP90AA1, ICAM1, JUN, NOS2, PPARG, PTGS1, PTGS2) were identified using a compound-influenza disease target network (C-D). Protein-protein interaction (PPI) network was constructed and we identified eight proteins from nine target genes formed a network. The compound-disease-pathway network (C-D-P) revealed three classes of pathways linked to influenza: cancer, viral diseases, and inflammation. Taken together, our systems biology data from C-T, C-D, PPI and C-D-P networks predicted potent compounds from FT and new therapeutic targets and pathways involved in influenza.     

国防信息基础设施的建设与管理

讨论了国防信息基础设施的概念,分析了美军国防信息基础设施的发展状况、实施方法、主要途径,提出了发展我军信息基础设施的技术途径和措施建议.     

AN ENHANCEMENT SCHEME OF TCP PROTOCOL IN MOBILE AD HOC NETWORKS： MME-TCP

Transmission Control Protocol （TCP） optimization in Mobile Ad hoc NETworks （MANETs） is a challenging issue because of some unique characteristics of MANETs. In this paper, a new end-to-end mechanism based on multiple metrics measurement is proposed to improve TCP performance in MANETs. Multi-metric Measurement based Enhancement of TCP （MME-TCP） designs the metrics and the identification algorithm according to the characteristics of MANETs and the experiment results. Furthermore, these metrics are measured at the sender node to reduce the overhead of control information over networks. Simulation results show that MME-TCP mechanism achieves a significant performance improvement over standard TCP in MANETs.     

基于多端口存储器互连结构的多处理器系统芯片设计

多处理器系统芯片设计的关键问题之一是微处理器之间的互连结构.在总线互连结构和开关互连结构之后,提出了基于多端口存储器的第3种互连结构.利用VHDL进行了多时钟多端口存储器设计,并利用EDA工具进行了片上系统芯片的多微处理器数据通讯的功能仿真.分析了基于总线、基于开关、基于多端口存储器的3种互连结构的特点.研究表明基于多端口存储器的互连结构具有异步数据传输,数据缓冲功能;具有数据传输延时小,多微处理器系统芯片的拓扑阵列规模可扩展的优点.     

EPON生存性分析和可存活网络拓扑研究

针对EPON系统的4种树型自愈结构和3种环形自愈结构保护方案进行了存活性能的比较分析,给出了其中能提供最好生存性的网络拓扑结构.