四川地区宫颈癌组织HPV18和HPV45 E6基因突变分析

采用聚合酶链反应技术对四川地区2003~2004年收集的60例宫颈癌患者的癌组织DNA进行人乳头瘤病毒(HPV) E6基因扩增, 获得HPV18和45型E6基因. 序列分析发现, 18型三例E6基因有同样的两处同义突变; 45型两例E6基因发生突变, 一例有两处碱基突变, 另一例发生六处碱基突变, 其中两处涉及氨基酸变化, 均位于E6抗原决定簇区. HPV45型E6基因中134位c→t, 157位c→t, 259位g→t和341位t→c的碱基点突变未见报道. 另外， 该地区HPV18和45型突变株之间存在碱基互变,  它们之间的最小差异比野生型HPV18和HPV45之间的差异小4.05%, 该数值比在非洲发现的突变株的要小很多, 该结果支持HPV18和HPV45可能起源于非洲的观点.     

The mathematics of scattering by unbounded,rough, inhomogeneous layers

In this paper we study, via variational methods, a boundary value problem for the Helmholtz equation modelling scattering of time harmonic waves by a layer of spatially varying refractive index above an unbounded rough surface on which the field vanishes. In particular, in the 2D case with TE polarization, the boundary value problem models the scattering of time harmonic electromagnetic waves by an inhomogeneous conducting or dielectric layer above a perfectly conducting unbounded rough surface, with the magnetic permeability a fixed positive constant in the medium. Via analysis of an equivalent variational formulation, we show that this problem is well-posed in two important cases: when the frequency is small enough; and when the medium in the layer has some energy absorption. In this latter case we also establish exponential decay of the solution with depth in the layer. An attractive feature is that all constants in our estimates are bounded by explicit functions of the index of refraction and the geometry of the scatterer.     

A note on Riemann problems for single‐periodic polyanalytic functions

In this article, a new canonical function has been established to deal with Riemann boundary‐value problem of periodic analytic functions discussed in 16 . In comparison with the corresponding result in 16 , the expression of solution obtained here is much simpler. Then, we demonstrate the equivalence of solutions for the homogeneous Riemann problem. What's more, we obtain the precise rank of matrix of coefficients for the system of linear algebraic equations (4.35) in 16 . Those results can simplify the discussion of Riemann problem of single‐periodic polyanalytic functions in 16 .     

45~#钢宽带激光淬火研究

:本文利用宽带CO2 激光束 ,对 45 #钢表面进行宽带淬火 ,获得单道淬火宽度 10mm以上。淬硬层硬度达 5 0 0～ 6 30Hv0 3是非淬硬层的 2～ 2 5倍 ,深度达 1 9～ 2 .0mm。激光淬硬层分为表面过热区、均匀相变区和过渡区三个区域 ,所对应的金相组织分别为高碳马氏体、隐晶马氏体和混和马氏体。宽带激光淬火造成的组织细化和大量高碳马氏体的形成是硬度提高的主要原因。在扫描速度v =4mm/s和离焦量 18mm条件下 ,45 #钢宽带激光淬火的最佳功率约为 3 0～ 3 3kW。     

Heteroclinic solutions for a class of the second order Hamiltonian systems

We shall be concerned with the existence of heteroclinic orbits for the second order Hamiltonian system , where q∈Rn and V∈C¹(R×Rn,R), V?0. We will assume that V and a certain subset M⊂Rn satisfy the following conditions. M is a set of isolated points and #M?2. For every sufficiently small ε>0 there exists δ>0 such that for all (t,z)∈R×Rn, if d(z,M)?ε then −V(t,z)?δ. The integrals , z∈M, are equi-bounded and −V(t,z)→∞, as |t|→∞, uniformly on compact subsets of Rn?M. Our result states that each point in M is joined to another point in M by a solution of our system.     

On approximation and representation of K-regularized resolvent families

We study the problem of approximation and representation for a family of strongly continuous operators defined in a Banach space. It allows us to extend, and in some cases to improve results from the theory ofC ₀-semigroups of operators to, among others, the theories of cosine families, n-times integrated semigroups, resolvent families and k-generalized solutions by means of an unified method.The author was supported by FONDECYT grants 1980812; 1970722 and DICYT (USACH).     

Estimates of densities for Lévy processes with lower intensity of large jumps

We obtain general lower estimates of transition densities of jump Lévy processes. We use them for processes with Lévy measures having bounded support, processes with exponentially decaying Lévy measures for large times and for processes with high intensity of small jumps for small times.     

用于1064nm波段的45°倾斜光纤光栅的研制及其偏振特性研究

研究分析了45°倾斜光纤光栅的工作机理。利用紫外曝光法,将周期为1070 nm的相位模板旋转一定角度后,在光敏光纤上成功写制了45°倾斜光纤光栅,通过拼接写制技术,写制的光栅栅区长度为24 mm。对写制的45°倾斜光纤光栅的偏振依赖损耗特性进行了研究,在1064 nm处偏振依赖损耗值为11.8 dB,在1050~1100 nm范围内的偏振依赖损耗值保持在9 dB以上。导致其偏振依赖损耗值偏低的主要原因为相位模板的周期不匹配以及光栅栅区长度不够。经过优化后该器件可作为光纤起偏器件使用。