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141.
142.
Some problems in using v-support vector machine (v-SVM) for the prediction of nonlinear time series are discussed. The problems include selection of various net parameters, which affect the performance of prediction, mixture of kernels, and decomposition cooperation linear programming v-SVM regression, which result in improvements of the algorithm. Computer simulations in the prediction of nonlinear time series produced by Mackey-Glass equation and Lorenz equation provide some improved results. 相似文献
143.
Zhuwei Wang Zhicheng Liu Lihan Liu Chao Fang Meng Li Jingcheng Zhao 《Entropy (Basel, Switzerland)》2022,24(5)
With the rapid development of wireless sensor technology, recent progress in wireless sensor and actuator networks (WSANs) with energy harvesting provide the possibility for various real-time applications. Meanwhile, extensive research activities are carried out in the fields of efficient energy allocation and control strategy design. However, the joint design considering physical plant control, energy harvesting, and consumption is rarely concerned in existing works. In this paper, in order to enhance system control stability and promote quality of service for the WSAN energy efficiency, a novel three-step joint optimization algorithm is proposed through control strategy and energy management analysis. First, the optimal sampling interval can be obtained based on energy harvesting, consumption, and remaining conditions. Then, the control gain for each sampling interval is derived by using a backward iteration. Finally, the optimal control strategy is determined as a linear function of the current plant states and previous control strategies. The application of UAV formation flight system demonstrates that better system performance and control stability can be achieved by the proposed joint optimization design for all poor, sufficient, and general energy harvesting scenarios. 相似文献
144.
145.
New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds
Crescenzo Coppa Luca Sorrentino Monica Civera Marco Minneci Francesca Vasile Sara Sattin 《Molecules (Basel, Switzerland)》2022,27(10)
Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such as those leading to antibiotic persistence, a bacterial bet-hedging strategy, will lead to new molecular entities displaying low selective pressure, thereby reducing the insurgence of AMR. Here, we describe a way to target (p)ppGpp (guanosine tetra- or penta-phosphate) signaling, a non-essential pathway involved in the formation of persisters, with a structure-based approach. A superfamily of enzymes called RSH (RelA/SpoT Homolog) regulates the intracellular levels of this alarmone. We virtually screened several fragment libraries against the (p)ppGpp synthetase domain of our RSH chosen model RelSeq, selected three main chemotypes, and measured their interaction with RelSeq by thermal shift assay and STD-NMR. Most of the tested fragments are selective for the synthetase domain, allowing us to select the aminobenzoic acid scaffold as a hit for lead development. 相似文献
146.
Jesús Gutirrez-Gutirrez Fernando M. Villar-Rosety Xabier Insausti Marta Zrraga-Rodríguez 《Entropy (Basel, Switzerland)》2022,24(5)
In the era of the Internet of Things, there are many applications where numerous devices are deployed to acquire information and send it to analyse the data and make informed decisions. In these applications, the power consumption and price of the devices are often an issue. In this work, analog coding schemes are considered, so that an ADC is not needed, allowing the size and power consumption of the devices to be reduced. In addition, linear and DFT-based transmission schemes are proposed, so that the complexity of the operations involved is lowered, thus reducing the requirements in terms of processing capacity and the price of the hardware. The proposed schemes are proved to be asymptotically optimal among the linear ones for WSS, MA, AR and ARMA sources. 相似文献
147.
148.
We study the characteristics of phase transition to take the top-priority of randomization in the rules of NaSch model (i.e.noise-first model) into account via computing the relaxation time and the order parameter.The scaling exponents of the relaxation time and the scaling relation of order parameter,respectively,axe obtained. 相似文献
149.
针对激光目标指示器在进行多目标指示时,激光束之间有相互干扰的缺点,提出了一种基于walsh矩阵的多目标指示激光束编码方案.walsh矩阵的每一行或每一列都相互正交,是伪随机序列,自相关值最大,而互相关值为0.哈达马序walsh矩阵的结构特点使得可编程电路很容易生成该矩阵的某一行或某一列.通过简单的数值设置,可以让不同的目标指示器生成Walsh矩阵的不同行,即得到不同的伪随机序列.利用伪随机序列的相关特性,使用walsh矩阵的不同行对激光束进行编码,则可消除激光束间的串扰.该方案具有抗干扰能力强、保密性好、易于实现等优点,也适用于多路遥控系统. 相似文献
150.