Statistical experimental design for bioprocess modeling and optimization analysis

The statistical design of experiments (DOE) is a collection of predetermined settings of the process variables of interest, which provides an efficient procedure for planning experiments. Experiments on biological processes typically produce long sequences of successive observations on each experimental unit (plant, animal, bioreactor, fermenter, or flask) in response to several treatments (combination of factors). Cell culture and other biotech-related experiments used to be performed by repeated-measures method of experimental design coupled with different levels of several process factors to investigate dynamic biological process. Data collected from this design can be analyzed by several kinds of general linear model (GLM) statistical methods such as multivariate analysis of variance (MANOVA), univariate ANOVA (timesplit-plot analysis with randomization restriction), and analysis of orthogonal polynomial contrasts of repeated factor (linear coefficient analysis). Last, regression model was introduced to describe responses over time to the different treatments along with model residual analysis. Statistical analysis of biprocess with repeated measurements can help investigate environmental factors and effects affecting physiological and bioprocesses in analyzing and optimizing biotechnology production.     

Magneto-optical specifications of Rosen-Morse quantum dot with screw dislocation

This is the first study to consider a quantum dot with screw dislocation that has Rosen-Morse (RM) confinement potential, generated by a GaAs/GaAlAs heterostructure. An external magnetic field and Aharonov-Bohm (AB) flux field were also applied on RM quantum dot (RMQD) in order to stave the effects of a screw dislocation defect. The combined effect of the screw dislocation defect, the external magnetic field, and AB flux field on the total refractive index changes (TRICs) and the total absorption coefficients (TACs) of RMQD are thus investigated. Cylindrical coordinates are used due to the direction of application of the torsion and the external fields, as well as due to the structure's symmetry. The effective mass approximation and tridiagonal matrix methods are used in order to obtain the subband energy spectra and electronic wave functions of RMQD. The nonlinear optical specifications of RMQD are checked using compact-density-matrix formalism within the framework of the iterative method. Reviews without screw dislocation are also carried out in order to be able to clarify the effects of a screw dislocation defect on the optical properties, and then, both cases are deliberated. This study is the first attempt to analyze the AB flux field for RMQD without screw dislocation. In the present study, the influences of a screw dislocation defect on RMQD's TRICs and TACs are probed by considering different values of the external magnetic field and AB flux field, and the ranges of corresponding parameters on the optimum of the structure are specified. Moreover, the study also elucidates how to rule out the effects of screw dislocation on optical specifications by means of the external fields. Despite a certain screw dislocation, the frequency range is determined where the structure behaves as if it is perfect (namely, without screw dislocation) for its optimum, which in turn is crucial for experimental applications.     

基于ARM处理器和μC/OS-Ⅱ操作系统的电子机箱智能监控技术

研究了基于ARM处理器和μC/OS-Ⅱ操作系统对VPX电子机箱实时智能监控的技术。完成了故障监测收集、控制、存储和上报,解决了VPX电子机箱故检和监控的技术问题,实现了VPX电子机箱的智能监控,方便故障定位和维修。     

OFDM系统中峰平功率比减小技术的研究

主要对减小OFDM系统中的峰值平均值功率比(PAPR)问题进行了研究。利用Golay互补序列和Reed-Muller码的关系,研究了一种把输入信息序列编成Golay互补序列的分组编码算法,并利用该编码算法对一个16子载波的OFDM系统的PAPR特性进行仿真。理论研究和仿真结果均表明,采用该编码方案后的OFDM信号的PAPR不超过3dB。     

不定期决策过程优化模型的算法研究

逆向算法是动态规划通常采用的寻优途径，但对于不定期决策过程，因其模型的不规范，算法不能通用。文章针对建立在不定期决策过程基础上的URM模型，提出了SPURM算法，该算法通过对URM模型进行分析转换．建立分段明晰、易地求解的RM模型，确定每个节点的位置及每段的状态变量集合，从而能够对该模型进行逆     

基于Q3标准的网络管理通信接口

Ｑ３接口是实现网络管理开放性和标准化的关键，它主要包括通信协议栈和公用管理知识两个方面，前者解决信息的传送，后者解决对信息的理解及管理功能的运用。文章最后给出了Ｑ３接口在ＨＰＯｐｅｎｖｉｅｗ平台的应用实例。     

ATM与异种计算机网络互连

在对比了ＡＴＭ网络结构与ＯＳＩ／ＲＭ网络模型异同的基础上，阐述了ＡＴＭ与异种计算机网络互连的基本原理，分析陋有协议对ＡＴＭ网络互连的支持，讨论了新一代ＩＰｖ６及路由器、ＡＴＭ交换机结合技术对ＡＴＭ互连网的推动。     

Optimal scaling factors for CM1 and CM3 atomic charges in RM1-based aqueous simulations

Scaling factors for atomic charges derived from the RM1 semiempirical quantum mechanical wavefunction in conjunction with CM1 and CM3 charge models have been optimized by minimizing errors in absolute free energies of hydration, ΔG_hyd, for a set of 40 molecules. Monte Carlo statistical mechanics simulations and free energy perturbation theory were used to annihilate the solutes in gas and in a box of TIP4P water molecules. Lennard–Jones parameters from the optimized potentials for liquid simulations‐all atom (OPLS–AA) force field were utilized for the organic compounds. Optimal charge scaling factors have been determined as 1.11 and 1.14 for the CM1R and CM3R methods, respectively, and the corresponding unsigned average errors in ΔG_hyd relative to experiment were 2.05 and 1.89 kcal/mol. Computed errors in aniline and two derivatives were particularly large for RM1 and their removal from the data set lowered the overall errors to 1.61 and 1.75 kcal/mol for CM1R and CM3R. Comparisons are made to the AM1 method which yielded total errors in ΔG_hyd of 1.50 and 1.64 kcal/mol for CM1A*1.14 and CM3A*1.15, respectively. This work is motivated by the need for a highly efficient yet accurate quantum mechanical (QM) method to study condensed‐phase and enzymatic chemical reactions via mixed QM and molecular mechanical (QM/MM) simulations. As an initial test, the Menshutkin reaction between NH₃ and CH₃Cl in water was computed using a RM1/TIP4P‐Ew/CM3R procedure and the resultant ΔG^?, ΔG_rxn, and geometries were in reasonable accord with other computational methods; however, some potentially serious shortcomings in RM1 are discussed. © 2011 Wiley Periodicals, Inc. J Comput Chem, 2011     

μC／OS-Ⅲ在80386保护模式下的移植

文章介绍了一种将μC／OS-Ⅲ移植到Intel80386处理器上,使其能够借助T-DOS的资源,在保护模式下正常运行的方法。通过解析内核相关代码、CPU相关代码和板级支持包代码这三部分代码,讲述了将实时操作系统μC／OS-Ⅲ移植到80386处理器保护模式下的全过程。最后给出了在保护模式下运行μC／OS-Ⅲ的实例。     

基于μC／OS Ⅱ的三维打印机任务间的通信技术研究

简要介绍了三维打印机原理与控制系统,重点论述了采用μC／OS Ⅱ操作系统开发三维打印机中任务的划分及任务间的通信技术。将三维打印分为4个用户任务,分别是触摸屏操作任务,显示屏显示任务,数据生成任务,打印任务。凭借μC／OS Ⅱ灵活的任务间通信的能力,采用消息邮箱Mbox从数据生成任务中将打印数据传送给打印任务。在不同任务中,将暂时不需要工作的任务挂起,而将需要工作的任务恢复运行,圆满地实现了三维打印的快速、精确控制。