Tb-MOFs在荧光检测方面的研究进展

镧系离子特殊的电子排布使镧系有机骨架材料（Ln-MOFs）具有独特的发光性质,通过骨架和不同客体分子间的相互作用,可实现对诸多物质的荧光检测。其中,以铽离子（Tb3+）为中心构筑的Tb-MOFs具有更优良的光学性能和更高的检测灵敏度,是一种极具潜力的高效荧光探针。本文以稀土Tb3+为主线,综述了近年来国内外Tb-MOFs材料在阴阳离子、有机小分子、生物分子荧光检测方面的研究进展,并对未来发展趋势进行了展望。     

超导纳米线单光子探测器件的制备

超导纳米线单光子探测器件(SNSPD)是超导单光子探测系统的核心器件。文中介绍了成功制备的基于5nm厚的NbN超导超薄薄膜的SNSPD器件。器件核心结构为150nm宽的纳米曲折线结构,纳米线条占空比为75%,面积为20μm×20μm。超导纳米线是利用电子束曝光(EBL)技术和反应离子刻蚀(RIE)等工艺技术制备的。所制备的SNSPD样品,在温度3.5K下的临界电流约12.9μA;在1310nm波长光波辐照,12.5μA的偏置电流下,探测效率约0.016%。     

暗物质理论研究进展

评述了天体物理中暗物质的发现以及标准模型所面临的问题,综述了解决这些问题及标准模型之外可能出现的新物理与暗物质的联系。介绍了暗物质粒子选择条件和可能的暗物质粒子的候选者;对圆柱形暗物质表面密度与星系和星系团暗物质晕的晕核半径的关系进行了讨论,与其他模型进行了比较,得出暗物质晕的特征半径r_*的暗物质表面密度分布不是一个普适量;并叙述了近几年暗物质研究中提出的新理论模型-Hidden dark matter,最后叙述了中国暗物质实验探测研究的进展,2016年底DAMPE的第一批数据有可能给出;中国锦屏地下实验室（CJPL）的CDEX和PandaX合作组的第一期实验没有发现暗物质粒子存在的信号,期待他们下期的实验。A review of the evidence of the dark matter found in universe and the problems faced by the standard model. To address these issues as well as the possible relationship between the new physics beyond the standard model and dark matter, and given the selection condition of dark matter and possible candidates of the weakly-interacting massive particles (WIMPs). The correlation between the column surface density and the halo core radius of the dark matter halos of galaxies and cluster of galaxies is discussed, and the other models are compared. We find that the surface density within the halo characteristic radius r* is not an universal quantity; The new model (hidden dark matter)proposed in the study of dark matter is described. At last, the research progress of dark matter experiment in China is commented. At the end of 2016, the first batch of DAMPE data may be given;No significant excess events of WIMPS were found in the first stage of both the CDEX and PandaX experiments located in the China Jinping Underground Laboratory(CJPL). Look forward to their the next stage of these experiments in CJPL.     

Determination of low analyte concentrations by near-infrared spectroscopy: effect of spectral pretreatments and estimation of multivariate detection limits

Near infrared spectroscopy (NIRS) was used in combination with partial least squares (PLS) calibration to determine low concentrated analytes. The effect of the orthogonal signal correction (OSC) and net analyte signal (NAS) pretreatments on the models obtained at concentrations of analyte near its detection limit was studied. Both pretreatments were found to accurately resolve the analyte signal and allow the construction of PLS models from a reduced number of factors; however, they provided no substantial advantage in terms of %RSE for the prediction samples. Multiple methodologies for the estimation of detection limits could be found in the bibliography. Nevertheless, detection limits were determined by a multivariate method based on the sample-specific standard error for PLS regression, and compared with the univariate method endorsed by ISO 11483. The two methods gave similar results, both being effective for the intended purpose of estimating detection limits for PLS models. Although OSC and NAS allow isolating the analyte signal from the matrix signal, they provide no substantial improvement in terms of detection limits. The proposed method was used to the determine 2-ethylhexanol at concentrations from 20 to 1600 ppm in an industrial ester. The detection limit obtained, round 100 ppm, testifies to the ability of NIR spectroscopy to detect low concentrated analytes.     

Preparation of a novel composite particles and its application in the fluorescent detection of proteins

A new fluorescence method for the detection of proteins with novel composite nanoparticles (CdS/PPA) has been developed. The composite nanoparticles have been prepared through an in-situ polymerization method under ultrasonic irradiation. The surface of the composite nanoparticles was covered with functional groups (-COOH). These groups may play a major role in the improving the water solubility and biocompatibility of the nanoparticles. The composite particles is combined with proteins in NaAc-HCl buffer solution (pH=1.99), which can result in strong fluorescence, and the response is linearly proportional to the concentration of proteins. In λem/λex=650 nm/365 nm place (the stoke’ shift is 285 nm), its fluorescent strength reaches the maximum. Under the optimum conditions, the linear range is 0.10–20.0 μg·ml⁻¹ with the detection limit of 41 ng·ml⁻¹ for HSA, and 0.10–15.0 μg·ml⁻¹ with the detection limit of 35 ng·ml⁻¹ for Human γ-IgG . The method has been applied to the determination of the total protein in human serum samples collected from the hospital and the results are satisfactory.     

X-ray Peltier cooled detectors for X-ray fluorescence analysis

The recent results on development of X-ray Si(Li), Si-planar and CdTe p-i-n detectors cooled by Peltier coolers for fabrication of laboratory and portable XRF analysers for different applications are discussed.

Low detection limits of XRF analysers are provided by increasing of detectors sensitive surface; improvement of their spectrometrical characteristics; decreasing of front-end-electronics noise level; Peltier coolers and vacuum chambers cooling modes optimization.

Solution of all mentioned tasks allowed to develop Peltier cooled detectors with the following performances:

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Advantages and disadvantages of all types of detectors for X-ray fluorescence analysis are compared. Spectra are presented. Application of different XRF analysers based on developed detectors in medicine, environmental science, industry, cryminalistics and history of art are demonstrated.     

Combined neural network and reduced FRF techniques for slight damage detection using measured response data

Summary  This paper deals with structural damage detection using measured frequency response functions (FRF) as input data to artificial neural networks (ANN). A major obstacle, the impracticality of using full-size FRF data with ANNs, was circumvented by applying a data-reduction technique based on principal component analysis (PCA). The compressed FRFs, represented by their projection onto the most significant principal components, were used as the ANN input variables instead of the raw FRF data. The output is a prediction of the actual state of the specimen, i.e. healthy or damaged. A further advantage of this particular approach is its ability to deal with relatively high measurement noise, which is a common occurrence when dealing with industrial structures. The methodology was applied to detect three different states of a space antenna: reference, slight mass damage and slight stiffness damage. About 600 FRF measurements, each with 1024 spectral points, were included in the analysis. Six 2-hidden layer networks, each with an individually-optimised architecture for a specific FRF reduction level, were used for damage detection. The results showed that it was possible to distinguish between the three states of the antenna with good accuracy, subject to using an adequate number of principal components together with a suitable neural network configuration. It was also found that the quality of the raw FRF data remained a major consideration, though the method was able to filter out some of the measurement noise. The convergence and detection properties of the networks were improved significantly by removing those FRFs associated with measurement errors. Received 9 March 2000; accepted for publication 12 December 2000     

Trace mercury (II) detection and separation in serum and water samples using a reusable bifunctional fluorescent sensor

In this work, a reusable bifunctional fluorescent sensor for simultaneous detection and separation of trace Hg²⁺ in water and serum, which contains a naphthalimide derivative of 2,6-bis(aminomethyl)pyridine covalently grafted to the surface of silica particles, was developed. Meanwhile, the fluorescence characteristics and the adsorbent properties of the sensor were investigated in detail. This sensor showed a very good linearity (correlation coefficient of R² = 0.9991) in the range 0.1-1 μM of Hg²⁺ with detection limits lower than 6.8 × 10⁻⁹ M. It can also be used as an adsorbent for the removal of mercuric ions from the contaminated aqueous solution. The regeneration of this sensor is very simple, only by modulating the pH value of the aqueous solution. It can be reused at least four cycles. In addition, the present approach has the advantages of rapidity, simplicity, and low cost. We believe that this approach may serve as a foundation for the preparation of practical fluorescent sensor for the rapid detection of Hg²⁺ in aqueous biological and environmental samples.     

入侵检测技术分析概述

入侵检测是计算机网络安全防御体系的重要内容之一 ,作为一种新的动态安全防御技术 ,它是继防火墙之后的第二道安全防线。综述入侵检测技术的主要方面性 ,为进一步研究提供参考。     

输出电流达200mA的双极性电流源

本文介绍一种稳幅式双极性电流源,它是根据自动控制原理设计而成的,用于连续铸造熔渣的检测.