Unique ion beam scattering technique on depth profile determination

Abstract

By combination of energy and time of flight detection in ERDA or NRA measurement, the particles' masses can be determined, additionally to the depth information. This leads to unique depth profile determination even for complex targets. Combination with th concept of Jacobi transformations results in extremely fast measurements. In this paper, a way is shown how this concept can be realized even for accelerators ofenergies as low as about 1 MeV.     

Rapid Chromatographic Analysis of Nucleosides and N-Bases in Physiologic Fluids

Abstract

A high-resolution anion-exchange system has been developed to analyze specifically for the nucleosides and bases present in physiologic fluids. This sytem employs a unique coupled-column operation that allows rapid column stripping and regeneration on completion of each run. Results obtained in the analysis of urine for nucleosides and bases are presented.     

Determination of Lead in Human Hair by High Resolution Continuum Source Graphite Furnace Atomic Absorption Spectrometry with Microwave Digestion and Solid Sampling

The content of lead in human hair was measured by high resolution continuum source graphite furnace atomic absorption spectrometry (HR-CS GFAAS) combined with microwave-assisted digestion (MAD) and direct solid sampling (DSS). Hair strands were washed, dried, and then cut into three parts (root, middle portion, and tip). For MAD-GFAAS assays, approximately 0.25 g of hair was completely digested using a mixture of concentrated nitric acid and hydrogen peroxide in a closed system. In the DSS-GFAAS assays, 0.1–0.2 mg of dried hair was directly introduced into a graphite furnace using a solid autosampler. The temperature programs were optimized and the effects of various added modifiers were compared. The results indicated that NH₄H₂PO₄ was the optimal modifier for analysis of Pb using GFAAS. Use of the optimal modifier and temperature program gave similar limits of detection for MAD-GFAAS and DSS-GFAAS of 1.16 ng/g and 0.82 ng/g, respectively. Both methods also produced satisfactory recoveries ranging from 98.69% to 103.14%. There was no significant difference observed between the Pb contents of hair strands determined by the MAD-GFAAS and DSS-GFAAS assays, which both indicated that the Pb levels increased along the hair strands. Comparison of the two methods revealed that DSS-GFAAS had several advantageous characteristics over MAD-GFAAS, including the need for much less sample material and having a less time-consuming procedure, lower sample blank absorbance, lower memory effect, and no risk of environmental pollution by digesting chemicals. The direct solid sampling technique can be employed as a good alternative to conventional wet digestion in AAS assays.     

Nash multiplicities and isolated points of maximum multiplicity

Let X be an algebraic variety defined over a field of characteristic zero, and let $\xi \in \underset{\_}{\mathrm{Max}}\mathrm{mult}(X)$ be a point in the closed subset of maximum multiplicity of X. We provide a criterion, given in terms of arcs, to determine whether ξ is isolated in $\underset{\_}{\mathrm{Max}}\mathrm{mult}(X)$. More precisely, we use invariants of arcs derived from the Nash multiplicity sequence to characterize when ξ is an isolated point in $\underset{\_}{\mathrm{Max}}\mathrm{mult}(X)$.     

MR microscopy of micron scale structures

Magnetic resonance (MR) microscopy of up to 1–5-μm resolutions have been reported previously. The tested phantom structures, however, had widths one order of magnitude bigger than the reported resolutions, e.g., spherical beads or capillary tubes of tens-of-micron diameters or wall thicknesses have been imaged. In this study, we fabricated structures having a few micron widths on a silicon wafer and imaged them using our 1-μm-resolution MR microscopy at 14.1 T. Micron scale width structures were, for the first time, resolved by MR microscopy.     

Precise Design of Millimeter Wave Quasi-Optical Faraday Rotators

A method of designing high performance millimeter wave quasi-optical Faraday rotators (QOFR) is reported in this paper. First, the dielectric and magnetic parameters for the ferrite sample are determined by fitting theoretical curves to the measured data. These fitted parameters are then used in a precise numerical model to predict the rotation angle and insertion loss of the QOFR. Finally, the parameters of the QOFR are optimized according to the requirements of devices. Examples are given showing the performance of the QOFR with an isolation better than 20 dB and an insertion loss less than 0.6 dB from 75 GHz to 95 GHz.     

Impact of geometry on stretchable meandered interconnect uniaxial tensile extension fatigue reliability

This work investigates the impact of geometry on the reliability of a high conductivity, meandered, stretchable interconnect. Meandered copper conductor interconnects of varying geometries that have been encapsulated into a PDMS matrix, are evaluated for reliability under tensile stretching conditions to 10% elongation. We present results that support our earlier findings by experiment and FEM simulation. Following, we vary interconnect parameters related to the encapsulation geometry, such as encapsulation hardness, thickness and stretchable zone perimeter, to assess impact on fatigue life of the embedded meandered copper lines. Results confirm and refine the prior simulation findings. Combinations of interconnect geometry parameters critical for stretching reliability are identified. Among others, we find that the meander radius (R) and encapsulation thickness are strongly coupled, causing very large meanders with thick encapsulation to fail very early. We show that, depending on the design of the meander transition, the characteristic life of an interconnect can differ 50 times under moderate, 10% cyclic elongation. Finally, we indicate the significance of our findings for the design of reliable, stretchable electronic systems.     

Rapid quantitative analysis of individual anthocyanin content based on high‐performance liquid chromatography with diode array detection with the pH differential method

A new quantitative technique for the simultaneous quantification of the individual anthocyanins based on the pH differential method and high‐performance liquid chromatography with diode array detection is proposed in this paper. The six individual anthocyanins (cyanidin 3‐glucoside, cyanidin 3‐rutinoside, petunidin 3‐glucoside, petunidin 3‐rutinoside, and malvidin 3‐rutinoside) from mulberry (Morus rubra) and Liriope platyphylla were used for demonstration and validation. The elution of anthocyanins was performed using a C₁₈ column with stepwise gradient elution and individual anthocyanins were identified by high‐performance liquid chromatography with tandem mass spectrometry. Based on the pH differential method, the high‐performance liquid chromatography peak areas of maximum and reference absorption wavelengths of anthocyanin extracts were conducted to quantify individual anthocyanins. The calibration curves for these anthocyanins were linear within the range of 10–5500 mg/L. The correlation coefficients (r²) all exceeded 0.9972, and the limits of detection were in the range of 1–4 mg/L at a signal‐to‐noise ratio ≥5 for these anthocyanins. The proposed quantitative analysis was reproducible with good accuracy of all individual anthocyanins ranging from 96.3 to 104.2% and relative recoveries were in the range 98.4–103.2%. The proposed technique is performed without anthocyanin standards and is a simple, rapid, accurate, and economical method to determine individual anthocyanin contents.     

Pressure drop effects on selectivity and resolution in packed column supercritical fluid chromatography

The influence of pressure drop on retention, selectivity, plate height and resolution was investigated systematically in packed supercritical fluid chromatography (SFC) using pure carbon dioxide as the mobile phase. Numerical methods developed previously which enabled the prediction of pressure gradients, diffusivities, capacity factors, plate heights and resolutions along the length of the column were used for the model calculations. The effects of inlet pressure and supercritical fluid flow rate on selectivity and resolution are studied. In packed column SFC with pure carbon dioxide as the mobile phase, the pressure drop can have a significant effect on resolution. The flow rate is shown to have a larger effect than generally realized. The calculated data are shown to be in good agreement with the experimental results. Finally, the variation of the chromatographic parameters along a 5.5 meter long model SFC column is illustrated. The possibilities and limitations of using long packed columns in SFC are discussed. It is demonstrated that long columns with large plate numbers do not necessarily yield better separations.