DBS包覆TiO2 纳米粒子的表面光伏及光致发光性能

The TiO2 nanoparticles capped with sodium dodecylbenzenesulfonate (DBS) were synthesized by a sol-hydrothermal method, and were also characterized by XRD, TEM, Surface Photovoltage Spectroscopy (SPS) and Photoluminescence (PL). The effects of capping DBS on photovoltage and photoluminescence performances of TiO2 nanoparticle as well as appropriate capping conditions were principally investigated. The results show that the capping situation is desirable when the pH value and adding DBS amount are in the range of 4.5-5.5 and 1.0%-3.0% of TiO2 weight in advance of the hydrothermal process, respectively. The added DBS could inhibit the growth of anatase crystallite during the hydrothermal process. Moreover, the intensities of SPS and PL of TiO2 nanoparticle decreased after DBS was capped, which is possibly attributed to the electrophilic property of sulfonic acid group (-SO3-) as well as the decrease of surface defect.     

分布式基站防雷研究

分布式基站具有RRU拉远的特点,给移动通信网络的安全运营带来了新的雷击风险和安全隐患.本文依据其防雷特点及差异性,结合现网实际运营经验,重点研究了分布式基站防雷保护的关键指标,如BBU/RRU设备雷击保护水平、交/直流馈电防雷系统配置、基站机房等电位连接、光缆的综合保护、GPS防雷要求等.     

基于ARM与μC/OS-Ⅱ的弯管流量计的研究与设计

嵌入式技术已经广泛用于工业领域,弯管流量计是工业领域里一种常见的流量计量仪器,文中将ARM与μC/OS-Ⅱ应用于弯管流量计中,利用实时操作系统的任务分配,来扩展弯管流量计的功能设计。实现了无纸记录仪,大容量数据存储转移,网络远程维护等功能。     

Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers

An early clinical development study (phase I) was conducted to determine the usefulness of dried blood spot (DBS) sampling as an alternative to venous sampling for phenotyping and genotyping of CYP450 enzymes in healthy volunteers. Midazolam (MDZ) was used as a substrate for phenotyping CYP3A4 activity; the concentrations of MDZ and its main metabolite 1'-hydroxymidazolam (1-OH MDZ) were compared between the DBS method from finger punctures, plasma and whole blood (WB), drawn by venipuncture, whereby several methodological parameters were studied (i.e. punch width, amount of dots analyzed and storage time stability). Genotyping between DBS and venous WB samples was compared for CYP2D6 (*3, *4, *6), CYP2C19 (*2, *3), CYP3A4 (*1B) and CYP3A5 (*3C). In addition, the subject's and phlebotomist's satisfaction with venous blood sampling compared with the DBS method was evaluated using a standardized questionnaire. An LC-MS/MS method for the quantification of the MDZ and 1-OH MDZ concentrations in DBS samples was developed and validated in the range of 0.100-100 ng/mL. No compromises were made for the limits of quantification of the DBS-LC-MS/MS method vs the authentic plasma and WB methods.     

In silico studies of 1,3(R):2,4(S)‐dibenzylidene‐D‐sorbitol as a gelator for polypropylene

The organic gelator 1,3(R):2,4(S)‐dibenzylidene‐D‐sorbitol (DBS) self‐organizes to form a 3‐D network at relatively low concentrations in a variety of nonpolar organic solvents and polymer melt. In this work, we have investigated the interactions between DBS molecules in polypropylene (PP) by molecular modeling. We have used quantum mechanics to elucidate the preferred geometry of one molecule and a dimer of DBS, and molecular mechanics and molecular dynamics to simulate pure DBS, pure PP, and mixture of DBS and PP as condensed phases, at various temperatures. It was found that inter‐ and intramolecular H‐bonds between DBS molecules are formed in PP in a much more pronounced manner than those formed in pure DBS. The most significant intermolecular H‐bonds are formed between the terminal hydroxyl groups. The most significant intramolecular H‐bonds are formed between O5 /H‐O6 groups. Due to the H‐bonds, DBS molecules form a rigid structure similar to liquid crystal forming molecules, which might explain their tendency to create nanofibrils. It seems that the aromatic rings do not contribute significantly to the intermolecular interactions. Their main role is probably to stiff the molecular structure. Temperature dependences of inter‐ and intramolecular interactions are different. Whereas intermolecular interactions peak heights decrease when temperature increases for pure DBS, the intramolecular interaction almost does not change. Copyright © 2012 John Wiley & Sons, Ltd.     

毫米波雷达DBS回波信号仿真

为了在实验室内完成多普勒波束锐化（DBS）技术的评估、验证及优化,阐述了多普勒波束锐化（DBS）技术的基本原理及DBS图像拼接算法,结合目标DBS回波理论模型及毫米波雷达的特点,采用Matlab工具对目标的DBS回波信号进行了计算机仿真,得到目标DBS回波数据,运用DBS成像技术完成回波仿真数据的成像处理,实现了不同波束内不同方位的目标回波仿真及成像,验证了DBS回波仿真算法的正确性。为DBS回波仿真的工程应用奠定了基础。     

Three-layer poly(methyl methacrylate) microsystem for analysis of lysosomal enzymes for diagnostic purposes

Lysosomal storage diseases are chronic, progressive and typically have a devastating impact on the patient and the family. The diagnosis of these diseases is still a challenge, however, even for trained specialists. Accurate diagnostic methods and high-throughput tools that could be readily incorporated into existing screening laboratories are urgently required.