基于泛洪约束的MANET按需组播路由协议

降低路由控制开销是MANET网络组播路由协议节省节点能量,提高带宽利用率的关键因素之一。本文研究了组播路径近邻节点对路由维护的作用以及链路的连通性,分别提出了一个新的泛k-洪约束算法和一个混合泛洪模式。基于泛k-洪约束算法和混合泛洪模式,提出一个新的按需组播路由协议ODMRP-CF,ODMRP-CF协议通过选择k-路由近邻节点转发泛洪分组来提高泛洪效率。ODMRP-CF协议不仅保持了ODMRP协议所具有的简单,对节点移动鲁棒性好的优点,而且有效地降低了ODMRP-CF协议的控制开销。     

基于最速下降法的车载网络功率控制研究

车载网络中的功率控制算法D-FPAV在功率值计算精度要求较高时,即计算功率值的步长取值较小时,存在计算量较大的问题。该文在D-FPAV算法的基础上提出了一种改进的功率控制算法最速下降功率控制SDPC算法,该算法运用了最速下降法快速收敛的原理。仿真结果表明,SDPC算法能够降低计算迭代次数,提高算法收敛速度,并且使得车辆发送状态信息的功率能够随车辆位置信息和环境的变化快速做出调整,从而能有效地进行信道拥塞控制,有利于提高车辆行驶的安全性。     

1,10-邻菲咯啉-5,6-二酮制备反应中副产物的形成与控制

由1,10-邻菲咯啉合成1,10-邻菲咯啉-5,6-二酮反应的副产物的形成与控制研究表明,1,10-邻菲咯啉在5,6位二酮化反应中的副反应产物及主产物分离时产生的副产物均为4,5-二氮杂芴-9-酮,二酮化反应条件(包括作为氧化剂的强混合酸H2SO4/HNO3的加入量、时间和温度)和主产物分离时体系的酸度对副产物的形成有重要影响,优化了二酮化反应条件和产物分离时的体系pH控制范围。在此优化条件下,可有效控制副产物的形成,使主产物1,10-邻菲咯啉-5,6-二酮的收率达到92%以上。     

天然高分子药物微球载体材料的研究进展

综述了国内外在天然高分子药物微球载体材料研究及应用中的进展状况,主要从天然高分子药物微球载体材料的分类、微球的制备方法及特点、载药微球的给药途径和应用等进行概括,并对目前所存在的问题进行了描述。     

YBO3:Eu荧光粉的水热法制备及形貌控制

用水热法在低于300℃成功地制备出具有不同形貌的YBO3:Eu3+荧光粉,其反应温度比固相反应了约800℃.研究了初始原料、pH值、反应温度、反应溶剂和催化剂等条件对目的产物形貌及粒度的,得到了具有Vaterite结构、粒度分布均匀的球形荧光粉的最佳合成工艺.在254nm激发下,水热法的球形Y0.95Eu0.05BO3荧光粉最强发射峰位于598nm处,属于Eu3+的5D0→7F1的跃迁,是固相反应所品的1.5倍.这些结果表明,在PDP和荧光灯等显示和照明用荧光粉的制备中水热法具有潜在的应用.     

分光光度法测定金属硅中铁的线性校正与受控下的不确定度评估

用分光光度法测定金属硅中铁量,来分析讨论如何采用基本方法和控制方法技术,进行校正函数的残差齐性方差检验和有效期间的受控分析。研究结果表明,采用控制方法可以确保测量不确定度尽可能小,以达到检测的最终要求。     

Identification,control strategies,and analytical approaches for the determination of potential genotoxic impurities in pharmaceuticals: A comprehensive review

Potential genotoxic impurities in pharmaceuticals at trace levels are of increasing concern to both pharmaceutical industries and regulatory agencies due to their possibility for human carcinogenesis. Molecular functional groups that render starting materials and synthetic intermediates as reactive building blocks for small molecules may also be responsible for their genotoxicity. Determination of these genotoxic impurities at trace levels requires highly sensitive and selective analytical methodologies, which poses tremendous challenges on analytical communities in pharmaceutical research and development. Experimental guidance for the analytical determination of some important classes of genotoxic impurities is still unavailable in the literature. Therefore, the present review explores the structural alerts of commonly encountered potential genotoxic impurities, draft guidance of various regulatory authorities in order to control the level of impurities in drug substances and to assess their toxicity. This review also describes the analytical considerations for the determination of potential genotoxic impurities at trace levels and finally few case studies are also discussed for the determination of some important classes of potential genotoxic impurities. It is the authors’ intention to provide a complete strategy that helps analytical scientists for the analysis of such potential genotoxic impurities in pharmaceuticals.     

Thermosensitive and control release behavior of poly(N-isopropylacrylamide-co-acrylic acid)/nano-Fe3O4 magnetic composite latex particle that is synthesized by a novel method

In this study, a novel method was used to synthesize the poly(N-isopropylacrylamide-co-acrylic acid)/Fe₃O₄ (poly(NIPAAm-AA)/Fe₃O₄) magnetic composite latex. The crosslinked poly(NIPAAm-AA) polymer latex particles were first synthesized by the method of soapless emulsion polymerization, then Fe²⁺ and Fe³⁺ ions were introduced to bond with the -COOH groups of AA segments in poly(NIPAAm-AA) polymer latex particles. Further by a reaction with NH₄OH, Fe₃O₄ nanoparticles were generated in situ. The concentrations of acrylic acid (AA), crosslinking agent (N,N′-methylene bisacrylamide (MBA)), and Fe₃O₄ nanoparticles were important factors to influence the morphology and lower critical solution temperature (LCST) of poly(NIPAAm-AA)/Fe₃O₄ magnetic composite latex particles. The poly(NIPAAm-AA)/Fe₃O₄ latex particles were used as a thermosensitive drug carrier to load caffeine. The control release of caffeine was studies. Morphology-based schematic models were proposed to explain the control release behavior of the composite particles with different compositions. Moreover, the protein (albumin, acetylated from bovine serum (BSA)) was bound on the surface of poly(NIPAAm-AA)/Fe₃O₄ composite latex particles. The effects of AA, crosslinking agent and Fe₃O₄ contents on the amount of BSA binding were investigated at different temperatures and pH values. The composition-morphology-BSA conjugation relationship was established.     

ZWK-100注塑机微机控制系统

ZWK-100注塑机微机控制系统,是新近研制开发的具有汉字和曲线显示功能,适用于1万克及其以上大型注塑机的微机电气控制系统.本文介绍其工作过程,硬软件结构及其性能等.     

Non-iterative optimal design of quantum controls

A non-iterative means for quantum control design is introduced with the aim of offering practical designs that can later be fine-tuned with laboratory closed-loop techniques. The procedure recognizes that Hamiltonians for realistic system control applications are rarely known accurately. The algorithm takes advantage of this fact by allowing for managed deviations in the equations of motion, thus removing the standard Lagrange multiplier. Suitable time-dependent cost functional weights are introduced that eliminate the traditional final time matching condition, thereby producing non-iterative design equations as an initial value problem. Removal of the final time condition also eliminates the demand that the target state be reached at any artificially imposed time. Tests on a simple molecular system indicate that the algorithm leads to well-behaved designs and that the weight functions are adequately estimated by order of magnitude analysis. Received 30 June 2000 and Received in final form 22 November 2000