Survey on differential privacy and its progress

With the arrival of the era of big data sharing,data privacy protection issues will be highlighted.Since its introduction in 2006,differential privacy technology has been widely researched in data mining and data publishing.In recent years,Google,Apple and other companies have introduced differential privacy technology into the latest products,and differential privacy technology has become the focus of academia and industry again.Firstly,the traditional centralized model of differential privacy was summarized,from the perspective of analysis of data mining and data released in the differential privacy way.Then the latest local differential privacy regarding data collection and data analysis based on the local model was described,involving crowdsourcing with random response technology,BloomFilter,statistical inference techniques.Finally,the main problems and solutions of differential privacy technology were summarized.     

A new SVM-based relevance feedback image retrieval using probabilistic feature and weighted kernel function

Relevance feedback (RF) is an effective approach to bridge the gap between low-level visual features and high-level semantic meanings in content-based image retrieval (CBIR). The support vector machine (SVM) based RF mechanisms have been used in different fields of image retrieval, but they often treat all positive and negative feedback samples equally, which will inevitably degrade the effectiveness of SVM-based RF approaches for CBIR. In fact, positive and negative feedback samples, different positive feedback samples, and different negative feedback samples all always have distinct properties. Moreover, each feedback interaction process is usually tedious and time-consuming because of complex visual features, so if too many times of iteration of feedback are asked, users may be impatient to interact with the CBIR system. To overcome the above limitations, we propose a new SVM-based RF approach using probabilistic feature and weighted kernel function in this paper. Firstly, the probabilistic features of each image are extracted by using principal components analysis (PCA) and the adapted Gaussian mixture models (AGMM) based dimension reduction, and the similarity is computed by employing Kullback–Leibler divergence. Secondly, the positive feedback samples and negative feedback samples are marked, and all feedback samples’ weight values are computed by utilizing the samples-based Relief feature weighting. Finally, the SVM kernel function is modified dynamically according to the feedback samples’ weight values. Extensive simulations on large databases show that the proposed algorithm is significantly more effective than the state-of-the-art approaches.     

基于LabVIEW机器视觉的迈克耳孙干涉仪实验

基于机器视觉设计了迈克耳孙干涉仪实验,采用机器视觉技术替代人眼对目标(干涉圆环)进行分析与测量,可有效避免因视觉疲劳而造成的测量错误.     

Simple matching vs linear assignment in scheduling models with positional effects: A critical review

This paper addresses scheduling models in which a contribution of an individual job to the objective function is represented by the product of its processing time and a certain positional weight. We review most of the known results in the area and demonstrate that a linear assignment algorithm as part of previously known solution procedures can be replaced by a faster matching algorithm that minimizes a linear form over permutations. Our approach reduces the running time of the resulting algorithms by up to two orders, and carries over to a wider range of models, with more general positional effects. Besides, the same approach works for the models with no prior history of study, e.g., parallel machine scheduling with deterioration and maintenance to minimize total flow time.     

Quantum chemical electron impact mass spectrum prediction for de novo structure elucidation: Assessment against experimental reference data and comparison to competitive fragmentation modeling

We investigate the success of the quantum chemical electron impact mass spectrum (QCEIMS) method in predicting the electron impact mass spectra of a diverse test set of 61 small molecules selected to be representative of common fragmentations and reactions in electron impact mass spectra. Comparison with experimental spectra is performed using the standard matching algorithms, and the relative ranking position of the actual molecule matching the spectra within the NIST‐11 library is examined. We find that the correct spectrum is ranked in the top two matches from structural isomers in more than 50% of the cases. QCEIMS, thus, reproduces the distribution of peaks sufficiently well to identify the compounds, with the RMSD and mean absolute difference between appropriately normalized predicted and experimental spectra being at most 9% and 3% respectively, even though the most intense peaks are often qualitatively poorly reproduced. We also compare the QCEIMS method to competitive fragmentation modeling for electron ionization, a training‐based mass spectrum prediction method, and remarkably we find the QCEIMS performs equivalently or better. We conclude that QCEIMS will be very useful for those who wish to identify new compounds which are not well represented in the mass spectral databases.     

三晶S350变频器在工业水洗机上的应用

工业水洗机要求变频器能提供高转矩、多段速、宽电压、自动转差补偿和方便的通讯方式;还要求性能稳定,能适应不同的布草水洗车间高温、高湿的环境;还要求通讯获取变频器的输出频率并转换为转速实时地显示出来,对不同的布草可以方便地设定所需的洗涤和脱水速度,并能很好地兼顾高转速和大转矩两个方面。三晶S350矢量变频器采用了V/F曲线自动调节技术,根据洗涤状况自动诊断及调整V/F曲线,能满足工业水洗机的上述工艺要求,我厂2008年首次在100kg型全自动水洗机上应用,运行至今,稳定可靠。     

Distance versus Capillary Flow Dynamics-Based Detection Methods on a Microfluidic Paper-Based Analytical Device (μPAD)

In recent years, there has been high interest in paper-based microfluidic sensors or microfluidic paper-based analytical devices (μPADs) towards low-cost, portable, and easy-to-use sensing for chemical and biological targets. μPAD allows spontaneous liquid flow without any external or internal pumping, as well as an innate filtration capability. Although both optical (colorimetric and fluorescent) and electrochemical detection have been demonstrated on μPADs, several limitations still remain, such as the need for additional equipment, vulnerability to ambient lighting perturbation, and inferior sensitivity. Herein, alternative detection methods on μPADs are reviewed to resolve these issues, including relatively well studied distance-based measurements and the newer capillary flow dynamics-based method. Detection principles, assay performance, strengths, and weaknesses are explained for these methods, along with their potential future applications towards point-of-care medical diagnostics and other field-based applications.     

FFLUX: Transferability of polarizable machine‐learned electrostatics in peptide chains

The fully polarizable, multipolar, and atomistic force field protein FFLUX is being built from machine learning (i.e., kriging) models, each of which predicts an atomic property. Each atom of a given protein geometry needs to be assigned such a kriging model. Such a knowledgeable atom needs to be informed about a sufficiently large environment around it. The resulting complexity can be tackled by collecting the 20 natural amino acids into a few groups. Using substituted deca‐alanines, we present the proof‐of‐concept that a given atom's charge can be modeled by a few kriging models only. © 2017 Wiley Periodicals, Inc.     

Single-Molecule Sensing of Acidic Catecholamine Metabolites Using a Programmable Nanopore

Acidic catecholamine metabolites, which could serve as diagnostic markers for many diseases, demonstrate an importance of accurate sensing. However, they share a highly similar chemical structure, which is a challenge in the design of sensing strategies. A nanopore may be engineered to sense these metabolites in a single molecule manner. To achieve this, a recently developed programmable nano-reactor for stochastic sensing (PNRSS) technique adapted with a phenylboronic acid (PBA) adaptor was applied. Three acidic catecholamine metabolites, including 3,4-dihydroxyphenylacetic acid (DOPAC), 3,4-dihydroxymandelic acid (DHMA) and 3-methoxy-4-hydroxymandetic acid (VMA) were investigated by PNRSS. Specifically, DHMA, which contains an α-hydroxycarboxylate moiety and an adjacent cis-hydroxyl groups on its benzene ring, reports two binding modes simultaneously resolvable by PNRSS. Assisted with the high resolution of PNRSS, direct regulation of these two binding modes by pH can also be observed. A custom machine learning algorithm was also developed to achieve automatic event classification.