低相噪DDS信号产生电路的设计

本文介绍了DDS的基本原理以及DDS芯片AD9852的功能特点.详细介绍了一种基于单片机和DDS的频率源电路的软硬件实现方案.利用单片机AT89C51控制DDS芯片AD9852,产生了一个低相位噪声的信号.在进行软硬件设计过程中,总结出了产生低相噪DDS信号的一些注意事项,对设计低相噪DDS信号产生电路有很大的帮助.     

基于无线传感网络的目标入侵监测系统设计

针对我国广阔的领土及漫长的边防无法实现大范围有效、灵活、低投入的值守警戒,设计了一种基于无线传感网络的目标入侵监测系统。以满足恶劣环境下大范围、长时间,信息准确的无人值守需求。并进行了相应的实验验证,结果表明,该系统可靠性好,功耗低,可实现目标自动监测。     

基于AD9911频率源的设计与实现

设计了一种由单片机PIC18LF4520控制DDS芯片AD9911的频率源电路。阐述了单片机控制DDS的软硬件实现方法,以及AD9911内部寄存器的配置要点。系统设计外围电路简单,可方便地实现对频率源电路输出频率、相位和工作模式的控制,输出信号频率范围为25~75 MHz。实验结果表明,该频率源具有输出频率精确、频率分辨率高和相位噪声低等特点,符合通信系统对频率源的设计要求。     

高速电压输出型对数放大器 AD831O

AD8310是AD公司生产的一种高速电压输出型对数放大器。它可对DC到440MHz的频率范围进行解调。在15ns内对接地负载的驱动电流可达25mA,且功耗极低。AD8310采用先进的压缩技术,其动态范围高达95dB,而误差仅为±3dB。该器件性能稳定且易于使用,外部不需其它重要元件。文中介绍了该芯片的内部结构、原理以及应用设计方法。     

新型ADC器件AD6652的配置

软件无线电是一种基于宽带A/D器件、高速DSP芯片,以软件为核心(Software-Oriented)的崭新的体系结构,A/D转换和数字下变频是其中非常重要的两个关键。对AD6652进行了配置,因其集成了DDC,使得ADC的数据输出在内部直接连接到接收器的DDC输入矩阵,从而简化了设计,减少了连接产生的寄生信号。     

AD9856在短波信号发生中的应用

短波通信是唯一不受网络枢纽和有源中继体制制约的远程通信手段．广泛应用于电报、电话、低速传真通信和广播等。短波信号是构建短波通信环境的基础,对研制短波通信设备和模拟电磁环境具有重要意义。给出采用AD9856设计的基于正交调制方法的短波信号发生模块,可为研究短波通信和模拟电磁环境提供借鉴。     

The influence of the memory effect on preparative separations using the amylose tris(3,5-dimethylphenylcarbamate) stationary phase

Acid/base mobile phase modifiers affect enantioseparations in ways that are not yet understood for the lack of systematic studies, which makes the scale-up of preparative separations difficult to predict. Shifts of the selectivity of certain pairs of enantiomers upon exposure of the column to these modifiers is amply documented. Furthermore, once the modifier has been removed from the mobile phase, the improved selectivity remains, this phenomenon has been named the memory effect. We selected four enantiomeric pairs for a systematic study of this memory effect. The selectivity of 4-chlorophenylalanine ethyl ester (4CPEE) improves after a solution of ethanesulfonic acid (ESA) is percolated through the column. The selectivity of propranolol HCl and Tröger's base increases after a solution of diiospropylethylamine is percolated through the column. The selectivity of these three pairs of enantiomers is inversely affected by percolation of the opposite acid/base solution. Each of these four compounds reached an equilibrium concentration that maintained the separation of the enantiomeric pairs. In contrast, the selectivity of trans-stilbene oxide (TSO) is not affected by either acid/base modifier. Preparative separations can be used to detect changes in the active surface of the chiral polymer stationary phase by measuring the change in selectivity and resolution when modifiers are used. Preparative method development was carried out on analytical columns and scale-up to 1 cm ID columns were performed in this study.     

The attempted stereoselective synthesis of chiral 2,2′-biindoline

The attempted first stereoselective synthesis of 2,2′-biindoline using a metathesis-Sharpless asymmetric dihydroxylation strategy results in the synthesis of the heterocycle in poor to modest stereoselectivity. Attempts to improve the ee by varying the heteroatom protecting groups in key intermediates did not enhance the outcome of the Sharpless AD reaction. Therefore a limitation of this AD reaction is the use of 1,4-substituted but-2-enes where these substituents are ortho-substituted aromatics.     

Enantioseparation of paroxetine intermediate on an amylose-derived chiral stationary phase by supercritical fluid chromatography

The enantioseparation of trans-3-ethoxycarbonyl-4-(4′-fluorophenyl)-1-methyl piperidine-2,6-dione (3), which is one of the important racemic precursors of trans-(−)-paroxetine, has been investigated using supercritical fluid chromatography on a Daicel Chiralpak AD column. Supercritical CO₂ modified with methanol, ethanol and 2-propanol were used as mobile phase. The influence of type and concentration of alcohol modifier on retention factor, enantioselectivity and resolution were studied. Among methanol, ethanol and 2-propanol, 2-propanol was proved to be the most favorable modifier, and 9.5% (v/v) of 2-propanol was the preferred concentration at which racemate 3 could be separated with resolution of 15.86 and retention factor of 6.323. The effects of pressure and temperature were investigated at 9.5% (v/v) of 2-propanol in the pressure range of 12–24 MPa and temperature range of 303.15–318.15 K. It was found that the lower pressure and temperature were favorable to the enantioseparation. Using van’t Hoff plot, the isoenantioselective temperature was calculated to be 410 K. The enantioseparation process was “enthalpically driven” under experimental conditions. Finally, the retention factors were satisfactorily correlated by a simplified lattice–fluid model with average absolute relative deviation (AARD%) of both enantiomers smaller than 1.76%.     

Aβ蛋白分泌酶抑制剂研究进展

Aβ蛋白是淀粉样前体蛋白的代谢产物,它在脑组织中含量的异常增加可能是诱发AD的主要因素.应用分泌酶抑制剂可有效减少Aβ的生成,缓解患者症状.本文综述了其中的β分泌酶抑制剂的研究进展.